The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Follicle-Stimulating Hormone/Luteinizing Hormone Ratio as an Independent Predictor of Response to Controlled Ovarian Stimulation
Open accessAbstract
Aim: To determine whether a follicle-stimulating hormone (FSH)/luteinizing hormone (LH) ratio over 3 in the setting of a normal FSH (<12 IU/l) is associated with a higher rate of failed controlled ovarian stimulation cycles. Design: Retrospective cohort. Materials & methods: A total of 676 patients were identified; 198 patients had a FSH/LH ratio >3 and 477 patients had a FSH/LH ratio <3. Exclusion criteria included: age >40 years; estradiol (E2) prime protocols; E2 at start >70 pg/ml; and FSH at start >12 IU/l. The main outcome measure was cycle cancellation. Results: An elevated FSH/LH ratio >3 was more likely to result in the individual's cycle cancelled (15 vs 5.24%; p = 0.0001). The total gonadotropin dosage was greater in the higher ratio versus lower ratio group (2636 vs 2242 IU; significant). Peak E2 was significantly lower in the FSH/LH >3 group (peak E2: 1635 vs 1942 pg/ml). Conclusion: The value of the FSH/LH ratio in patients with normal FSH levels, may have a role in determining the appropriate stimulation protocol and predict cycle cancellations.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Furthermore, correlates of endometriosis, including low LH to FSH ratios, short AGD, and early menarche, predict poor response to ovarian stimulation in women without endometriosis (Fabregues et al., 2018; Kofinas & Elias, 2014; Prasad et al., 2013; Sadrzadeh et al., 2003; Shrim et al., 2006).”
From Endometriosis and polycystic ovary syndrome are diametric disorders (2021) · cites this paper as Kofinas & Elias, 2014
Citations
Cites
A systematic review of tests predicting ovarian reserve and IVF outcome
Broekmans, F. J., Kwee, J., Hendriks, D. J., Mol, B. W., & Lambalk, C. B. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml034 · Cited by 1,258
Bancsi, L. F. J. M. M., Broekmans, F. J. M., Eijkemans, M. J. C., de Jong, F. H., Habbema, J. D. F., & te Velde, E. R. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(01)02983-1 · Cited by 441
Muttukrishna, S., McGarrigle, H., Wakim, R., Khadum, I., Ranieri, D. M., & Serhal, P. (2005) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2005.00670.x · Cited by 304
Licciardi, F. L., Liu, H.-C., & Rosenwaks, Z. (1995) · Fertility and Sterility · doi:10.1016/s0015-0282(16)57916-3 · Cited by 295
Jayaprakasan, K., Campbell, B., Hopkisson, J., Johnson, I., & Raine-Fenning, N. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.10.042 · Cited by 261
Eldar-Geva, T., Ben-Chetrit, A., Spitz, I. M., Rabinowitz, R., Markowitz, E., Mimoni, T., Gal, M., Zylber-Haran, E., & Margalioth, E. J. (2005) · Human Reproduction · doi:10.1093/humrep/dei203 · Cited by 255
Evaluation of anti-Müllerian hormone as a test for the prediction of ovarian reserve
Kwee, J., Schats, R., McDonnell, J., Themmen, A. P. N., de Jong, F. H., & Lambalk, C. B. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.07.1293 · Cited by 201
McIlveen, M., Skull, J., & Ledger, W. J. (2006) · Human Reproduction · doi:10.1093/humrep/del435 · Cited by 154
Evers, J. L. H., Slaats, P., Land, J. A., Dumoulin, J. C. M., & Dunselman, G. A. J. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00080-6 · Cited by 106
Mukherjee, T., Copperman, A. B., Lapinski, R. H., Sandler, B., Bustillo, M., & Grunfeld, L. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58159-x · Cited by 100
Research works printed but not linked: 3
- de Carvalho BR, 2011, Clin. Exp. Obstet. Gynecol., 38, 119
- Liang X, 2001, Zhonghua Yi Xue Za Zhi, 81, 819
- Prasad S, 2013, J. Reprod Infertil., 14, 23
Cited by
Endometriosis and polycystic ovary syndrome are diametric disorders
Dinsdale, N. L., & Crespi, B. J. (2021) · Evolutionary Applications · doi:10.1111/eva.13244 · Cited by 90
“Furthermore, correlates of endometriosis, including low LH to FSH ratios, short AGD, and early menarche, predict poor response to ovarian stimulation in women without endometriosis (Fabregues et al., 2018; Kofinas & Elias, 2014; Prasad et al., 2013; Sadrzadeh et al., 2003; Shrim et al., 2006).”
BackgroundAn, G., Chen, X., Li, C., Zhang, L., Wei, M., Chen, J., Ma, Q., Yang, D., & Wang, J. (2020) · BioMed Research International · doi:10.1155/2020/4701563 · Cited by 45
“In addition, FSH/LH > 3 was found in the heat exposure group, indicating ovarian hyporesponsiveness or ovarian insufficiency [30].”
BackgroundRacoubian, E., Aimagambetova, G., Finan, R., & Almawi, W. (2020) · BMC Women's Health · doi:10.1186/s12905-020-00998-4 · Cited by 18
“laboratory predictor of diminished ovarian reserve and forecaster of response to controlled ovarian stimulation [30].”
BackgroundMethodGonzález-Rodríguez, A., Bernardo, M., Penadés, R., Arias, B., Cortés, V. R., Seeman, M. V., & Catalán, R. (2017) · Archives of Women s Mental Health · doi:10.1007/s00737-017-0757-2 · Cited by 15
“It predicts response to controlled ovarian stimulation (Forman et al. 1991; Kofinas and Elias 2014), as well as outcome of in vitro fertilization (Prasad et al. 2013; Seckin et al. 2012), even when FSH levels are within normal limits (Lyu et al. 2013).”
BackgroundZhou, S.-J., Zhao, M.-J., Li, C., & Su, X.-J. (2020) · Medicine · doi:10.1097/md.0000000000021979 · Cited by 15
“0001) and that the total gonadotropin dosage was greater in the higher-ratio group than in lower-ratio group (2636 vs 2242IU; significant).([31]) Finally, we did not collect data on embryo quality and pregnancy outcome associated with parameters in this research.”
Background
Metadata
- Authors
- Kofinas, J. D., & Elias, R. T.
- Affiliations
- NewYork–Presbyterian Hospital (US)
- Weill Cornell Medicine (US)
- ORCID
- Elias, Rony T
- Venue
- Women's Health
- Publisher
- SAGE Publications
- Published
- 2014-09
- Volume
- 10
- Issue
- 5
- Pages
- 505-509
- ISSN
- 1745-5057 (ISSN-L)
- 1745-5065
- OpenAlex
- W2101749651
- Cited by
- 21
- References
- 22
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 2 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 1
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
- Locations
- Women s Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- FSH/LH ratio, controlled ovarian stimulation, cycle cancellation, ovarian response prediction, gonadotropin dose, peak estradiol, in vitro fertilization, ovarian reserve
- MeSH terms
- Adult, Female, Fertilization in Vitro, Follicle Stimulating Hormone, Ovarian Follicle, Humans, Infertility, Female, Luteinizing Hormone, Ovary, Ovulation, Ovulation Induction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Follicle-Stimulating Hormone/Luteinizing Hormone Ratio as an Independent Predictor of Response to Controlled Ovarian Stimulation. https://app.cochat.ai/papers/10.2217/whe.14.31
- The paper
- Kofinas, J. D., & Elias, R. T. (2014). Follicle-Stimulating Hormone/Luteinizing Hormone Ratio as an Independent Predictor of Response to Controlled Ovarian Stimulation. Women's Health. https://doi.org/10.2217/whe.14.31
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
