THE JUVENILE HORMONE. II. ITS ROLE IN THE ENDOCRINE CONTROL OF MOLTING, PUPATION, AND ADULT DEVELOPMENT IN THE CECROPIA SILKWORM
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1. By means of a standardized "pupal assay" for juvenile hormone, the endocrine activity of the corpora allata was found to undergo large and systematic changes during the postembryonic development of the Cecropia silkworm. 2. In each of the larval instars that were studied, the glands are least active just prior to the larval molt and most active shortly after the molt. Larval molting therefore appears to take place in the presence of a declining titer of juvenile hormone—an endocrine situation which apparently permits the striking changes in morphology and pigmentation which occur in successive larval stages of the Cecropia silkworm. 3. The corpora allata show low but definite activity at the time of pupation. If the glands are extirpated so that pupation occurs in the absence of juvenile hormone many larval tissues overleap the pupal stage and undergo precocious adult differentiation. Therefore, the low concentration of juvenile hormone in the mature larva plays a definite role in the endocrine control of pupation. 4. The corpora allata are inactive throughout the entire pupal stage. This inactivity persists during the first two-thirds of adult development. During the final week of adult development, the glands recover their endocrine function and are maximally active by the time of emergence of the adult moth. 5. The absence of juvenile hormone proves to be an obligatory feature of the initial phase of adult differentiation. If active corpora allata are implanted into a p…
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JH transiently reappears during the prepupal stage, where it is primarily needed by the imaginal discs and primordia.
“JH transiently reappears during the prepupal stage, where it is primarily needed by the imaginal discs and primordia.”
From Regulation of metamorphosis in holometabolous insects (2026) · cites this paper as [66]
In the absence of prepupal JH, some primordia undergo adult, rather than pupal differentiation.
“In its absence, some primordia undergo adult, rather than pupal differentiation [66].”
From Regulation of metamorphosis in holometabolous insects (2026) · cites this paper as [66]
Inhibitory interactions between broad and E93, and a return of JH in the prepupa, ensure that Broad and pupa formation occur before E93 and adult differentiation.
“Inhibitory interactions between broad and E93, and a return of JH in the prepupa, ensure that Broad and pupa formation occur before E93 and adult differentiation.”
From Regulation of metamorphosis in holometabolous insects (2026) · cites this paper as [66]
The imaginal discs and primordia are the main tissues that require JH during the formation of the pupa.
“The imaginal discs and primordia are the main tissues that require JH during the formation of the pupa (e.g. [66]).”
From Regulation of metamorphosis in holometabolous insects (2026) · cites this paper as [66]
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References 22 · Cited by 272
- Authors
- WILLIAMS, C. M.
- Affiliations
- Harvard University (US)
- Corresponding author
- WILLIAMS, CARROLL M.
- Venue
- The Biological Bulletin
- Publisher
- University of Chicago Press
- Published
- 1961-12
- Volume
- 121
- Issue
- 3
- Pages
- 572-585
- ISSN
- 0006-3185 (ISSN-L)
- 1939-8697
- OpenAlex
- W2298510992
- Cited by
- 272
- References
- 22
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 6 · 2023: 4 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 6 · 2014: 8 · 2013: 7 · 2012: 6
- FWCI
- 17.08
- Type
- journal article
- Language
- en
- Open access
- Licence
- cc-by-nc-sa
- Locations
- Biological Bulletin (publishedVersion)
- Biodiversity Heritage Library (Smithsonian Institution) (submittedVersion, cc-by-nc-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Silkworms and Sericulture Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Insect and Arachnid Ecology and Behavior
- Keywords
- juvenile hormone, Bombyx mori, corpora allata, molting, pupation, adult development, metamorphosis, ecdysone, postembryonic development, larval instars, hormonal regulation, larval coloration, larval morphology, genetic reprogramming
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