High Contents of Trimethylamine Oxide Correlating With Depth in Deep-Sea Teleost Fishes, Skates, and Decapod Crustaceans

In muscles of shallow-living marine animals, the osmolyte trimethylamine N-oxide (TMAO) is reportedly found (in millimoles of TMAO per kilogram of tissue wet weight) at 30-90 in shrimp, 5-50 in crabs, 61-181 in skates, and 10-70 in most teleost fish. Recently our laboratory reported higher levels…