The DOI matches its Crossref record.
The Design and Analysis of Sequential Clinical Trials.
Abstract
Clinical Trials. Allocating Patients to Treatments. Measurement of Treatment Difference. The Design of a Sequential Trial Using the Boundaries Approach. The Analysis of a Sequential Trial. Alternative Approaches to the Design and Analysis of Sequential Clinical Trials. Prognostic Factors. The Comparison of More than Two Treatments. Implementation of Sequential Methods: Some Examples. References. Appendix. Index.
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Cited by
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A modified test for small‐study effects in meta‐analyses of controlled trials with binary endpoints
Harbord, R. M., Egger, M., & Sterne, J. A. C. (2006) · Statistics in Medicine · doi:10.1002/sim.2380 · Cited by 2,267
Comparison of Dopamine and Norepinephrine in the Treatment of Shock
De Backer, D., Biston, P., Devriendt, J., Madl, C., Chochrad, D., Aldecoa, C., Brasseur, A., Defrance, P., Gottignies, P., & Vincent, J.-L. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0907118 · Cited by 1,940
Mercat, A., Richard, J.-C. M., Vielle, B., Jaber, S., Osman, D., Diehl, J.-L., Lefrant, J.-Y., Prat, G., Richecoeur, J., Nieszkowska, A., et al. (2008) · JAMA · doi:10.1001/jama.299.6.646 · Cited by 1,344
Clinical trials in head injury
Narayan, R. K., Michel, M. E., Ansell, B., Baethmann, A., Biegon, A., Bracken, M. B., Bullock, M. R., Choi, S. C., Clifton, G. L., Contant, C. F., et al. (2002) · Journal of Neurotrauma · doi:10.1089/089771502753754037 · Cited by 913
Metadata
- Authors
- Harrington, D., & Whitehead, J.
- Venue
- Journal of the American Statistical Association
- Publisher
- JSTOR
- Published
- 1985-03
- Volume
- 80
- Issue
- 389
- Pages
- 244
- ISSN
- 0162-1459 (ISSN-L)
- OpenAlex
- W2099090406
- Cited by
- 634
- References
- 0
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Design and Analysis of Sequential Clinical Trials. https://app.cochat.ai/papers/10.2307/2288093
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- Harrington, D., & Whitehead, J. (1985). The Design and Analysis of Sequential Clinical Trials. Journal of the American Statistical Association. https://doi.org/10.2307/2288093
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
