The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Significance Testing to Establish Equivalence between Treatments, with Special Reference to Data in the Form of 2 x 2 Tables
Abstract
In this paper, the role of significance testing in establishing equivalence between treatments is described. In place of the more customary null hypothesis of no difference between treatments, the hypothesis that the true difference is equal to a specified delta is tested. The particular case of comparing two binomial samples is described in detail. Results using a method due to Gart and approximations based on the chi2 and normal distributions are compared. It is found that the test based upon chi2 with continuity correction agrees best overall with Gart's (1971) test and is therefore recommended for use when computational facilities needed for carrying out the latter are not available.
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Citations
Cites
Note on an Exact Treatment of Contingency, Goodness of Fit and Other Problems of Significance
Freeman, G. H., & Halton, J. H. (1951) · Biometrika · doi:10.2307/2332323 · Cited by 954
Cited by
Piaggio, G., Elbourne, D. R., Pocock, S. J., Evans, S. J. W., Altman, D. G., & CONSORT Group, F. T. (2012) · JAMA · doi:10.1001/jama.2012.87802 · Cited by 2,428
Reporting of Noninferiority and Equivalence Randomized Trials: An Extension of the CONSORT Statement
Piaggio, G., Elbourne, D. R., Altman, D. G., Pocock, S. J., Evans, S. J. W., & CONSORT Group, F. T. (2006) · JAMA · doi:10.1001/jama.295.10.1152 · Cited by 1,153
Bayesian approaches to randomized trials
Spiegelhalter, D. J., Freedman, L. S., & Parmar, M. K. B. (1994) · Journal of the Royal Statistical Society. Series A (Statistics in Society) · doi:10.2307/2983527 · Cited by 720
Farrington, C. P., & Manning, G. (1990) · Statistics in Medicine · doi:10.1002/sim.4780091208 · Cited by 657
Tryon, W. W. (2001) · Psychological Methods · doi:10.1037/1082-989x.6.4.371 · Cited by 391
Metadata
- Authors
- Dunnett, C. W., & Gent, M.
- Venue
- Biometrics
- Publisher
- JSTOR
- Published
- 1977-12
- Volume
- 33
- Issue
- 4
- Pages
- 593
- ISSN
- 0006-341X (ISSN-L)
- OpenAlex
- W1989750897
- Cited by
- 389
- References
- 1
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dunnett, C. W., & Gent, M. (1977). Significance Testing to Establish Equivalence between Treatments, with Special Reference to Data in the Form of 2 x 2 Tables. Biometrics. https://doi.org/10.2307/2529457
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
