The DOI matches its Crossref record.
The Design and Analysis of Sequential Clinical Trials.
Abstract
Clinical Trials. Allocating Patients to Treatments. Measurement of Treatment Difference. The Design of a Sequential Trial Using the Boundaries Approach. The Analysis of a Sequential Trial. Alternative Approaches to the Design and Analysis of Sequential Clinical Trials. Prognostic Factors. The Comparison of More than Two Treatments. Implementation of Sequential Methods: Some Examples. References. Appendix. Index.
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Cited by
Dose-ranging study of riluzole in amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis/Riluzole Study Group II, Lacomblez, L., Bensimon, G., Meininger, V, Leigh, P. N., & Guillet, P. (1996) · The Lancet · doi:10.1016/s0140-6736(96)91680-3 · Cited by 1,301
Monitoring clinical trials: Conditional or predictive power?
Spiegelhalter, D. J., Freedman, L. S., & Blackburn, P. R. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90003-6 · Cited by 307
Spiegelhalter, D. J., & Freedman, L. S. (1986) · Statistics in Medicine · doi:10.1002/sim.4780050103 · Cited by 276
The alpha spending function approach to interim data analyses
DeMets, D. L., & Lan, G. (1995) · Cancer Treatment and Research · doi:10.1007/978-1-4615-2009-2_1 · Cited by 58
Metadata
- Authors
- Prescott, R. J., & Whitehead, J.
- Venue
- Biometrics
- Publisher
- JSTOR
- Published
- 1983-12
- Volume
- 39
- Issue
- 4
- Pages
- 1128
- ISSN
- 0006-341X (ISSN-L)
- OpenAlex
- W2798011490
- Cited by
- 182
- References
- 0
- FWCI
- 8.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Design and Analysis of Sequential Clinical Trials. https://app.cochat.ai/papers/10.2307/2531365
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- Prescott, R. J., & Whitehead, J. (1983). The Design and Analysis of Sequential Clinical Trials. Biometrics. https://doi.org/10.2307/2531365
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.