The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Issues and Epidemiological Evidence regarding Radiation-Induced Thyroid Cancer
Abstract
The available information on the induction of thyroid cancer in humans by ionizing radiation is summarized and weaknesses or gaps in assessing risk are identified. Issues to be addressed include: average estimates of thyroid cancer risk from external irradiation, the effects of age on thyroid cancer induction, shape of the dose-response curve for acute irradiation, magnitude of risk at low doses, effects of dose fractionation or dose protraction, the relative effectiveness of iodine-131 (131I) in inducing thyroid cancer compared to external radiation, the temporal course of radiogenic thyroid cancer risk, mortality caused by thyroid cancer, host-susceptibility factors for radiogenic thyroid cancer, and biological factors in risk. It is concluded that the most important needs are to obtain more information on thyroid cancer risks following low-level or highly fractionated radiation exposures and following 131I exposure in children.
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“Two cases of thyroid cancer were reported compared to 0.1 cases expected over that period of time.”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [360]
In the citing paper
“In one study, an analysis was carried out of 602 individuals exposed to RAI below 20 years of age in Swedish and U.S. populations (360).”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [360]
In the citing paper
“The average follow-up period was 10 years, and the mean administered activity of RAI to the thyroid was 88 Gy (approximately 80 lCi/g or 2.96 MBq/g equivalent), an activity known to be associated with thyroid neoplasia and below that recommended for treatment of GD.”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [360]
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Metadata
- Authors
- Shore, R. E.
- Affiliations
- NYU Langone Health (US)
- Corresponding author
- Shore, Roy E.
- ORCID
- Shore, Roy E.
- Venue
- Radiation Research
- Publisher
- JSTOR
- Published
- 1992-07
- Volume
- 131
- Issue
- 1
- Pages
- 98
- ISSN
- 0033-7587 (ISSN-L)
- OpenAlex
- W2006336560
- Cited by
- 263
- References
- 83
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 7 · 2017: 3 · 2016: 8 · 2015: 7 · 2014: 5 · 2013: 5 · 2012: 10
- FWCI
- 6.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Radiation Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r37ca043175-07, 5p30ca013343-19)
- National Cancer Institute (CA 13343, CA43175)
- National Institute of Environmental Health Sciences (ES00260, P30ES000260)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Physical Sciences › Environmental Science › Pollution › Radioactive contamination and transfer
- Keywords
- radiation-induced thyroid cancer, ionizing radiation, thyroid cancer risk, dose-response relationship, low-dose radiation, dose fractionation, iodine-131, external irradiation, age effects, host susceptibility, thyroid cancer mortality, children
- MeSH terms
- Age Factors, Dose-Response Relationship, Radiation, Environmental Exposure, Humans, Iodine Radioisotopes, Neoplasms, Radiation-Induced, Radioactive Fallout, Risk, Thyroid Neoplasms, Meta-Analysis as Topic
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