Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion

Braun, Matthias, Ramracheya, Reshma, Bengtsson, Martin, Zhang, Quan, Karanauskaite, Jovita, Partridge, Chris, Johnson, Paul R., Rorsman, Patrik·2008·Diabetes

Cited by (366)

Items 201–300 of 366

  1. Analyzing electrical activities of pancreatic β cells using mathematical models
    Chae Young Cha, Trevor Powell, Akinori Noma · 2011 · Progress in Biophysics and Molecular Biology
  2. Mitochondrial Calcium Signaling in Pancreatic β-Cell
    Anna Weiser, J. Feige, U. de Marchi · 2021 · International Journal of Molecular Sciences
  3. In‐depth analysis of proteomic and genomic fluctuations during the time course of human embryonic stem cells directed differentiation into beta cells
    Bogdan Budnik, Juerg Straubhaar, John M. Neveu, Dmitry E. Shvartsman · 2022 · PROTEOMICS
  4. Insulin Release Mechanism Modulated by Toxins Isolated from Animal Venoms: From Basic Research to Drug Development Prospects
    Beatriz Elena Sarmiento, Luis Felipe Santos Menezes, Elisabeth F. Schwartz · 2019 · Molecules
  5. Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification
    Katarzyna Maleńczyk, Edit Szodorai, R. Schnell, G. Lubec, G. Szabó, T. Hökfelt, T. Harkany · 2018 · Molecular Metabolism
  6. Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells
    J. Santo-Domingo, Isabelle Chareyron, L. Dayon, Antonio Núñez Galindo, Ornella Cominetti, M. P. Giménez, U. de Marchi, C. Cantó, M. Kussmann, A. Wiederkehr · 2017 · The FASEB Journal
  7. Ca(2+)-dependent desensitization of insulin secretion by strong potassium depolarization.
    M. Willenborg, M. Belz, K. Schumacher, Alexandra Paufler, K. Hatlapatka, I. Rustenbeck · 2012 · American Journal of Physiology. Endocrinology and Metabolism
  8. Novel spliced variants of large-conductance Ca(2+)-activated K(+)-channel β2-subunit in human and rodent pancreas.
    S. Ohya, Tomohiro Fujimori, Takuya Kimura, H. Yamamura, Y. Imaizumi · 2010 · Journal of Pharmacological Sciences
  9. Neonatal Diabetes in Patients Affected by Liang-Wang Syndrome Carrying KCNMA1 Variant p.(Gly375Arg) Suggest a Potential Role of Ca2+ and Voltage-Activated K+ Channel Activity in Human Insulin Secretion
    C. Mameli, R. Cazzola, L. Spaccini, V. Calcaterra, M. Macedoni, P. A. La Verde, E. D'Auria, E. Verduci, G. Lista, G. Zuccotti · 2021 · Current Issues in Molecular Biology
  10. Concise Whole-Cell Modeling of BKCa-CaV Activity Controlled by Local Coupling and Stoichiometry.
    F. Montefusco, A. Tagliavini, M. Ferrante, M. G. Pedersen · 2017 · Biophysical Journal
  11. Microfluidic platform for assessing pancreatic islet functionality through dielectric spectroscopy.
    Khalil Heileman, J. Daoud, C. Hasilo, M. Gasparrini, S. Paraskevas, M. Tabrizian · 2015 · Biomicrofluidics
  12. Inhibition of the malate–aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion
    Jelena Stamenkovic, Lotta E. Andersson, Alice E. Adriaenssens, Annika Bagge, Vladimir V. Sharoyko, Fiona Mary Gribble, Frank M. Reimann, Claes B. Wollheim, Hindrik Mulder, Peter Spégel · 2015 · Biochemical Journal
  13. Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation.
    A. I. Fernández-Mariño, C. Porras-González, P. González-Rodríguez, J. Selent, M. Pastor, J. Ureña, A. Castellano, M. Valverde, J. Fernández-Fernández · 2012 · Cardiovascular Research
  14. Ca-induced Ca Release from Internal Stores in INS-1 Rat Insulinoma Cells.
    K. Choi, Sun-Cho Dong, J. Kim, B. Kim, Kyung Moo Lee, S.-H. Kim, Dong Kwan Kim, Se Hoon Kim, H. Park · 2011 · Korean Journal of Physiology and Pharmacology
  15. N-type Ca(2+) -channels in murine pancreatic beta-cells are inhibited by an exclusive coupling with somatostatin receptor subtype 1.
    Paul A. Smith · 2009 · Endocrinology
  16. Therapeutic Potential of Calcium Channel Blockers in Neuropsychiatric, Endocrine and Pain Disorders
    Aarish Manzar, Aleksandar Sič, Crystal Banh, N. Knezevic · 2025 · Cells
  17. The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus
    Lang Wen, Xiaoli Yang, Zujun Wu, Shumei Fu, Yaxi Zhan, Zuolong Chen, Danlei Bi, Yong Shen · 2023 · Cell Reports
  18. Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped
    Tariq Mohammad, Arnaldo Henrique de Souza, Mohammed Bensellam, Heeyoung Chae, Manon Jaffredo, Anne-Françoise Close, Jean-Philippe Deglasse, Laila R.B. Santos, Antoine Buémi, Nizar I. Mourad et al. · 2022 · Diabetologia
  19. Possible New Strategies for the Treatment of Congenital Hyperinsulinism
    J. Sikimić, T. Hoffmeister, Anne Gresch, Julia K. Kaiser, W. Barthlen, C. Wolke, I. Wieland, U. Lendeckel, P. Krippeit-Drews, M. Düfer et al. · 2020 · Frontiers in Endocrinology
  20. KCNH6 protects pancreatic β‐cells from endoplasmic reticulum stress and apoptosis
    Jing-Kai Lu, Han Shen, Qi Li, Feng-Ran Xiong, Rong-Rong Xie, Ming-Xia Yuan, Jin-Kui Yang · 2020 · The FASEB Journal
  21. Enhanced expression of β cell CaV3.1 channels impairs insulin release and glucose homeostasis
    Jia Yu, Yue Shi, Kaixuan Zhao, Guang Yang, Lina Yu, Yuxin Li, Eva-Marie Andersson, Carina Ämmälä, Shao-Nian Yang, P. Berggren · 2019 · Proceedings of the National Academy of Sciences of the United States of America
  22. Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception
    S. Soriano, Minerva Gil-Rivera, L. Marroquí, P. Alonso-Magdalena, E. Fuentes, J. Gustafsson, A. Nadal, J. Martinez-Pinna · 2019 · Scientific Reports
  23. Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis
    Jerod S. Denton, David Aaron Jacobson · 2011 · Trends in Endocrinology and Metabolism
  24. Venom Peptides, Polyphenols and Alkaloids: Are They the Next Antidiabetics That Will Preserve β-Cell Mass and Function in Type 2 Diabetes?
    Michele Lodato, V. Plaisance, V. Pawlowski, M. Kwapich, A. Barras, Emeline Buissart, S. Dalle, S. Szunerits, J. Vicogne, R. Boukherroub et al. · 2023 · Cells
  25. Calcium modulation of exocytosis-linked plasma membrane potential oscillations in INS-1 832/13 cells.
    A. Gerencser, H. Mulder, D. Nicholls · 2015 · Biochemical Journal
  26. Western blot analysis of BK channel β1‐subunit expression should be interpreted cautiously when using commercially available antibodies
    Yogesh Bhattarai, Roxanne N. Fernandes, M. Kadrofske, Lizbeth Lockwood, J. Galligan, Hui Xu · 2014 · Physiological Reports
  27. Molecular mechanism responsible for sex differences in electrical activity of mouse pancreatic β cells
    Noelia Jacobo-Piqueras, Tamara Theiner, Stefanie M. Geisler, P. Tuluc · 2024 · JCI Insight
  28. Model of Calcium Dynamics Regulating $$IP_{3}$$ I P 3 , ATP and In
    Vaishali, N. Adlakha · 2024 · Acta Biotheoretica
  29. The BK Channel Limits the Pro-Inflammatory Activity of Macrophages
    Yihe Chen, Nikita Markov, Lea Gigon, Aref Hosseini, Shída Yousefi, Darko Stojkov, Hans‐Uwe Simon · 2024 · Cells
  30. Loss of Znt8 function in diabetes mellitus: risk or benefit?
    C. Barragán-Álvarez, E. Padilla-Camberos, N. Díaz, A. Cota-Coronado, Claudia Hernández-Jiménez, C. Bravo-Reyna, N. E. Díaz-Martínez · 2021 · Molecular and Cellular Biochemistry
  31. Regulatory effects of protein S-acylation on insulin secretion and insulin action
    L. Chamberlain, M. Shipston, G. Gould · 2021 · Open Biology
  32. Involvement of the γ1 subunit of the large-conductance Ca2+-activated K+ channel in the proliferation of human somatostatinoma cells.
    Sayuri Noda, K. Chikazawa, Yoshiaki Suzuki, Y. Imaizumi, H. Yamamura · 2020 · Biochemical and Biophysical Research Communications - BBRC
  33. Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells
    Li Xie, Subhankar Dolai, Youhou Kang, T. Liang, H. Xie, Tai-Ran Qin, Lu Yang, Liang-Yi Chen, H. Gaisano · 2016 · PLoS ONE
  34. CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum
    Guang Yang, Yue Shi, Jia Yu, Yuxin Li, Lina Yu, A. Welling, F. Hofmann, J. Striessnig, L. Juntti-Berggren, P. Berggren et al. · 2014 · Cellular and Molecular Life Sciences
  35. Late sodium current (INaL) in pancreatic β-cells
    R. Rizzetto, M. Rocchetti, Luca Sala, Carlotta Ronchi, Alice Villa, M. Ferrandi, I. Molinari, F. Bertuzzi, A. Zaza · 2014 · Pflügers Archiv: European Journal of Physiology
  36. Modeling Mechanisms of Cell Secretion
    K. Tsaneva-Atanasova, H. Osinga, J. Tabak, M. G. Pedersen · 2010 · Acta Biotheoretica
  37. Studies of first phase insulin secretion using imposed plasma membrane depolarization
    Ingo Rustenbeck · 2010 · Frontiers in Bioscience-Scholar
  38. Electrical activity and exocytotic correlates of biphasic insulin secretion from β-cells of canine islets of Langerhans: Contribution of tuning two modes of Ca<sup>2+</sup>entry-dependent exocytosis to two modes of glucose-induced electrical activity
    Misler, Stanley, Zhou, Zhuan, Dickey, Adam S., Silva, Amelia M., Pressel, David M., Barnett, David W. · 2009 · Channels
  39. A computational systems analysis of factors regulating α cell glucagon secretion
    Fridlyand, Leonid E., Philipson, Louis H. · 2012 · Islets
  40. Beta cell primary cilia mediate somatostatin responsiveness via SSTR3
    Samantha E. Adamson, Zi-Peng A. Li, Jing W. Hughes · 2023 · Islets
  41. RyR2/IRBIT regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line INS-1
    Kyle E. Harvey, Emily K. LaVigne, M. S. Dar, Amy E. Salyer, Evan P. S. Pratt, Paxton A. Sample, U. Aryal, H. Gowher, G. Hockerman · 2021 · Scientific Reports
  42. Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by Ca2+ Channels
    F. Montefusco, M. G. Pedersen · 2018 · Comput. Math. Methods Medicine
  43. On depolarization-evoked exocytosis as a function of calcium entry: possibilities and pitfalls.
    M. G. Pedersen · 2011 · Biophysical Journal
  44. Lessons from models of pancreatic β cells for engineering glucose-sensing cells
    Arthur Sherman · 2010 · Mathematical Biosciences
  45. Glucose-induced [Ca2+]i oscillations in β cells are composed of trains of spikes within a subplasmalemmal microdomain
    Georg Langlhofer, Alexander Kögel, Michael Schaefer · 2021 · Cell Calcium
  46. Novel roles for voltage‐gated T‐type Ca 2+ and ClC‐2 channels in phagocytosis and angiogenic factor balance identified in human iPSC‐derived RPE
    Daria V. Mamaeva, Zhour Jazouli, Mattia Lorenzo DiFrancesco, Nejla Erkilic, Grégor Dubois, Cécile Hilaire, Isabelle Meunier, Hassan Boukhaddaoui, Vasiliki Kalatzis · 2021 · The FASEB Journal
  47. Voltage-Gated Na+ Channels are Modulated by Glucose and Involved in Regulating Cellular Insulin Content of INS-1 Cells
    Chong Chen, Song-Hua Wang, Qingjuan Hu, Lvming Zeng, Hai-Long Peng, Chao Liu, Li-Ping Huang, Hao Song, Yu-Ping Li, Li-Hua Yao et al. · 2018 · Cellular Physiology and Biochemistry
  48. Stromal Interaction Molecule 1 (STIM1) Regulates ATP-sensitive Potassium (KATP) and Store-operated Ca2+ Channels in MIN6 β-Cells*
    C. A. Leech, R. Kopp, Heather A. Nelson, J. Nandi, M. Roe · 2016 · Journal of Biological Chemistry
  49. Noncanonical Regulation of cAMP-dependent Insulin Secretion and Its Implications in Type 2 Diabetes
    S. Ramanadham, J. Turk, Sushant Bhatnagar · 2023 · Comprehensive Physiology
  50. Examining Mechanisms for Voltage-Sensitive Calcium Channel-Mediated Secretion Events in Bone Cells
    Perla Citlali Reyes Fernandez, Christian S. Wright, Mary C. Farach‐Carson, William R. Thompson · 2023 · Calcified Tissue International
  51. Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages
    A. Selezneva, Minae Yoshida, A. Gibb, D. Willis · 2021 · Pharmacological Reports
  52. UGGT1 retains proinsulin in the endoplasmic reticulum in an arginine dependent manner
    Jaeyong Cho, Masaki Hiramoto, Yuka Masaike, Satoshi Sakamoto, Yoichi Imai, Yumi Imai, Hiroshi Handa, Takeshi Imai · 2020 · Biochemical and Biophysical Research Communications
  53. Gap-junction coupling and ATP-sensitive potassium channels in human β -cell clusters: Effects on emergent dynamics
    Alessandro Loppini, Morten Gram Pedersen, M. Braun, Simonetta Filippi · 2017 · Physical review. E
  54. Imaging Large Cohorts of Single Ion Channels and Their Activity
    Katia Hiersemenzel, E. Brown, R. Duncan · 2013 · Frontiers in Endocrinology
  55. A novel impedance-based cellular assay for the detection of anti-calcium channel autoantibodies in type 1 diabetes.
    Michael W. Jackson, T. Gordon · 2010 · JIM - Journal of Immunological Methods
  56. The impact of sulfonylureas on diverse ion channels: an alternative explanation for the antidiabetic actions
    Xian-Tao Li, Meng-Ze Yun · 2025 · Frontiers in Cell and Developmental Biology
  57. Beta cell specific ZnT8 gene deficiency and resulting loss in zinc content significantly improve insulin secretion.
    A. Piro, Yihan Luo, Ziyi Zhang, Wenyue W Ye, Fei Kang, Xie Li, Yufeng Wang, F. Dai, H. Gaisano, J. Rocheleau et al. · 2024 · Molecular and Cellular Endocrinology
  58. Potassium voltage-gated channel subfamily H member 2 (KCNH2) is a promising target for incretin secretagogue therapies
    Yingchao Yuan, Hao Wang, Ze-Ju Jiang, Chang Liu, Qi Li, Si-Rui Zhou, Jin‐Kui Yang · 2024 · Signal Transduction and Targeted Therapy
  59. Macromolecules from mushrooms, venoms, microorganisms, and plants for diabetes treatment - Progress or setback?
    A. Chbel, Ayoub Lafnoune, Imane Nait Irahal, N. Bourhim · 2024 · Biochimie
  60. A primer on modelling pancreatic islets: from models of coupled β-cells to multicellular islet models
    Gerardo J. Félix‐Martínez, José Rafael Godínez-Fernández · 2023 · Islets
  61. Secretory granule exocytosis and its amplification by cAMP in pancreatic β-cells
    Mototsugu Nagao, Jens O. Lagerstedt, Lena Eliasson · 2022 · Diabetology International
  62. Insight into T-type calcium channel structure, function and modulation.
    Dan Wang, L. Ragnarsson, R. Lewis · 2020 · Current Medicinal Chemistry
  63. Interaction between pancreatic β cell and electromagnetic fields: A systematic study toward finding the natural frequency spectrum of β cell system
    Sajjad Farashi · 2017 · Electromagnetic Biology and Medicine
  64. The αβδ of ion channels in human islet cells
    Matthias Braun · 2009 · Islets
  65. Engineering the pancreatic niche: Mechanobiological insights into stem cell-derived β-cell therapy for diabetes mellitus
    Swaminadhan Dandapani, Yongsung Hwang · 2026 · Mechanobiology
  66. Endoplasmic Reticulum Calcium Mediates Drosophila Wing Development
    L. George, Mikaela L. Follmer, Emily Fontenoy, Hannah R. Moran, Jeremy Brown, Yunus H. Ozekin, E. Bates · 2023 · Bioelectricity
  67. The Dynamics of Calcium Signaling in Beta Cells—A Discussion on the Comparison of Experimental and Modelling Data
    Michael Müller, Jonas Walkling, N Seemann, Ingo Rustenbeck · 2023 · International Journal of Molecular Sciences
  68. Aromatase and non-aromatase neurons in the zebra finch secondary auditory forebrain are indistinct in their song-driven gene induction and intrinsic electrophysiological properties
    C. de Bournonville, Kyssia Ruth Mendoza, L. Remage-Healey · 2021 · European Journal of Neuroscience
  69. Protein Kinase CK2 Controls CaV2.1-Dependent Calcium Currents and Insulin Release in Pancreatic β-cells
    Rebecca Scheuer, S. Philipp, A. Becker, Lisa Nalbach, Emmanuel Ampofo, M. Montenarh, C. Götz · 2020 · International Journal of Molecular Sciences
  70. Recovery of viable endocrine‐specific cells and transcriptomes from human pancreatic islet‐engrafted mice
    Sambra D. Redick, Linda Leehy, A. Rittenhouse, David M. Blodgett, Alan G. Derr, Alper Kucukural, M. Garber, L. Shultz, D. Greiner, Jennifer P. Wang et al. · 2019 · The FASEB Journal
  71. Effects of polysaccharide from Portulaca oleracea L. on voltage-gated Na+ channel of INS-1 cells.
    Qingjuan Hu, Yu-Ping Li, Chao Liu, Li-Ping Huang, Lvming Zeng, Song-Hua Wang, Hao Song, Hai-Long Peng, Jian-Hua Huang, Chong Chen et al. · 2018 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  72. Toxins that Modulate Ionic Channels as Tools for Exploring Insulin Secretion
    C. M. Díaz-García, C. Sánchez-Soto, M. Hiriart · 2010 · Cellular and molecular neurobiology
  73. The signalling role of action potential depolarization in insulin secretion: metabolism-dependent dissociation between action potential increase and secretion increase by TEA.
    M. Willenborg, H. Ghaly, Kathrin Hatlapatka, K. Urban, U. Panten, I. Rustenbeck · 2010 · Biochemical Pharmacology
  74. Ion channels underlying stimulus-exocytosis coupling and its cell-to-cell heterogeneity in β-cells of transplantable porcine islets of Langerhans
    Amélia M. Silva, A. Dickey, D. Barnett, S. Misler · 2009 · Channels
  75. KCNH6 channel promotes insulin exocytosis via interaction with Munc18-1 independent of electrophysiological processes
    Hao Wang, Qi Li, Yinghua Yuan, Xue-Chun Han, Yong Cao, Jin-Kui Yang · 2024 · Cellular and Molecular Life Sciences
  76. Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip
    Amal Essaouiba, R. Jellali, Françoise Gilard, B. Gakière, T. Okitsu, C. Legallais, Yasuyuki Sakai, E. Leclerc · 2022 · Metabolites
  77. A genome-wide CRISPR screen identifies regulators of beta cell function involved in type 2 diabetes risk
    A. Grotz, Elena Navarro-Guerrero, R. Bevacqua, R. Baronio, Soren K. Thomsen, Sameena Nawaz, Varsha Rajesh, Agata Wesolowska-Andersen, Seung K. Kim, D. Ebner et al. · 2021 · bioRxiv
  78. Ion Channels as Therapeutic Targets for Type 1 Diabetes Mellitus
    Chandrabose Selvaraj, Gurudeeban Selvaraj, Satyavani Kaliamurthi, William Chi Shing Cho, Dong‐Qing Wei, Sanjeev Kumar Singh · 2019 · Current Drug Targets
  79. Lrrc55 is a novel prosurvival factor in pancreatic islets
    Guneet Makkar, Vipul Shrivastava, Brittyne Hlavay, Marle Pretorius, Barry D. Kyle, Andrew P. Braun, Francis C. Lynn, Carol Huang · 2019 · American Journal of Physiology-Endocrinology and Metabolism
  80. High‐fat‐diet‐induced remission of diabetes in a subset of K ATP ‐GOF insulin‐secretory‐deficient mice
    Zihan Yan, Zeenat A. Shyr, Manuela Fortunato, Alecia Welscher, Mariana Alisio, Michael R. Martino, Brian N. Finck, Hannah Conway, Maria Sara Remedi · 2018 · Diabetes Obesity and Metabolism
  81. BK potassium channel mRNA level changes in gills of Atlantic salmon after brackish water transfer
    C. Loncoman, J. Saravia, L. Gutiérrez, C. Contreras, R. Oyarzún, P. Strobel, Ricardo Enríquez, A. Isla, J. Figueroa, L. Vargas-Chacoff et al. · 2018
  82. On the emergent dynamics and synchronization of β -cells networks in response to space-time varying glucose stimuli
    Alessandro Loppini, Christian Cherubini, Simonetta Filippi · 2018 · Chaos Solitons & Fractals
  83. Biphasic voltage‐dependent inactivation of human NaV1.3, 1.6 and 1.7 Na+ channels expressed in rodent insulin‐secreting cells
    Mahdieh Godazgar, Quan Zhang, Margarita V. Chibalina, Patrik Rorsman · 2018 · The Journal of Physiology
  84. Modeling the spatiotemporal distribution of Ca2+ during action potential firing in human pancreatic β-cells
    G. J. Félix-Martínez, J. R. Godínez-Fernández · 2017 · Biomedical Physics & Engineering Express
  85. Loss of tetraspanin‐7 expression reduces pancreatic β‐cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism
    K. McLaughlin, S. Acreman, Sameena Nawaz, J. Cutteridge, A. Clark, J. G. Knudsen, Geoffrey Denwood, A. Spigelman, J. E. Manning Fox, S. P. Singh et al. · 2022 · Diabetic Medicine
  86. Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection
    Jessica R. Chaffey, Jay Young, K. Leslie, Katie M. Partridge, P. Akhbari, Shalinee Dhayal, Jessica L. Hill, Kyle C. A. Wedgwood, Edward C. Burnett, M. Russell et al. · 2021 · Scientific Reports
  87. Cannabinoid receptors are differentially regulated in the pancreatic islets during the early development of metabolic syndrome
    Antonio Barajas-Martínez, K. Bermeo, Lizbeth de la Cruz, M. Martínez-Vargas, Ricardo Jesus Martínez-Tapia, D. E. Garcia, L. Navarro · 2020 · Islets
  88. Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications
    Lena Eliasson, Jonathan L.S. Esguerra, Anna Wendt · 2017 · Diabetology International
  89. It takes two T to shape immunity: emerging role for T-type calcium channels in immune cells.
    Ľ. Lacinová, Norbert Weiss · 2016 · General Physiology and Biophysics
  90. Modeling Ca(2+) currents and buffered diffusion of Ca(2+) in human β-cells during voltage clamp experiments.
    G. J. Félix-Martínez, J. R. Godínez-Fernández · 2015 · Mathematical Biosciences
  91. Calcium Current Inactivation Rather than Pool Depletion Explains Reduced Exocytotic Rate with Prolonged Stimulation in Insulin-Secreting INS-1 832/13 Cells
    M. G. Pedersen, V. Salunkhe, E. Svedin, A. Edlund, L. Eliasson · 2014 · PLoS ONE
  92. Bioelectronic Sensing of Insulin Demand
    Matthieu Raoux, Guilherme Bontorin, Yannick Bornat, Jochen Lang, Sylvie Renaud · 2011 · Wiley eBooks
  93. The Kv2.2 channel mediates the inhibition of prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells
    Chengfang Pan, Ying Liu, Liangya Wang, Wen-Yong Fan, Yunzhi Ni, Xuefeng Zhang, Di Wu, Chenyang Li, Jin Li, Zhaoyang Li et al. · 2024 · bioRxiv
  94. Simultaneous TIRF imaging of subplasmalemmal Ca2+ dynamics and granule fusions in insulin-secreting INS-1 cells reveals coexistent synchronized and asynchronous release.
    Charlotte Suckert, Carolin Zosel, Michael Schaefer · 2024 · Cell Calcium
  95. Machine learning provides insight into models of heterogeneous electrical activity in human beta-cells
    Daniele Andrean, Morten Gram Pedersen · 2022 · Mathematical Biosciences
  96. Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction
    Xi Yan, Ze-Ping Zhao, Jeremy D. Weaver, T. Sun, J. Yun, C. Roneker, Feng-Hua Hu, N. Doliba, C. C. Mccormick, M. Vatamaniuk et al. · 2022 · Redox Biology
  97. Membrane polarization in non-neuronal cells as a potential mechanism of metabolic disruption by depolarizing insecticides.
    Yeonhwa Park, A. Suvorov, S. Symington, J. M. Clark · 2022 · Food and Chemical Toxicology
  98. The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on [Formula: see text] dynamics.
    Maryam Saadati, Y. Jamali · 2020 · Scientific Reports
  99. Electrophysiological models of the human pancreatic δ‐cell: From single channels to the firing of action potentials
    G. J. Félix-Martínez, V. González-Vélez, J. R. Godínez-Fernández, Amparo Gil · 2019 · International Journal for Numerical Methods in Biomedical Engineering
  100. Lung Based Engineered Micro-Pancreas Sustains Human Beta Cell Survival and Functionality
    Orit Goldman, Dmitry Puchinsky, K. Durlacher, R. Sancho, B. Ludwig, P. Kugelmeier, C. Heller, Nikolai Kunicher, S. Bornstein, A. Treves · 2019 · Hormone and Metabolic Research