Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis
Reed, Alison S., Unger, Elizabeth K., Olofsson, Louise E., Piper, Merisa L., Myers, Martin G., Xu, Allison W.·2010·Diabetes
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- The metabolic effects of leptin therapy and glucagon suppression therapy in mouse models of diabetesNeumann, Ursula Hope · 2017 · cIRcle (University of British Columbia)
- Effects of pro-inflammatory cytokines on central actions of leptin and insulinEugenia Mc Allister · 2014 · Repository for Publications and Research Data (ETH Zurich)
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- A High Multivitamin Diet Fed To Wistar Rat Dams During Pregnancy Increases Later Life Maternal Weight Gain and Alters Homeostatic, Hedonic and Peripheral Regulatory Systems of Energy Balance.Emanuela Pannia · 2014 · TSpace (University of Toronto)
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