Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets
Ramracheya, Reshma, Ward, Caroline, Shigeto, Makoto, Walker, Jonathan N., Amisten, Stefan, Zhang, Quan, Johnson, Paul R., Rorsman, Patrik +1 more·2010·Diabetes
Cited by (123)
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- Zinc Homeostasis and the Risk of Type 2 Diabetes: Complex Role of ZnT8 in Insulin and Glucagon Secretion.Fateme Ghafouri-Taleghani, Z. Bahadoran · 2026 · Current nutrition reports
- Paracrine inhibition via G protein inwardly rectifying potassium channels regulates glucagon secretion from human pancreatic alpha cellsJ. Panzer, A. Lang, Noah J Levi, P. Garcia, Rene Barro-Soria, Alejandro Caicedo · 2026 · Cell Reports
- On the Electrophysiological Component of Pancreatic Alpha-Cell ModelsH. E. Romero-Campos, G. Dupont, V. González-Vélez · 2021 · Annual International Conference of the IEEE Engineering in Medicine and Biology Society
- Heterogenous impairment of α-cell function in type 2 diabetes is linked to cell maturation stateXiao-Qing Dai, J. Camunas-Soler, L. Briant, Theodore dos Santos, A. Spigelman, Emily M. Walker, R. A. Drigo, Austin Bautista, Robert C. Jones, J. Lyon et al. · 2021 · bioRxiv
- Postnatal refinement of CaV channel isoform composition, electrical activity, and insulin release in mouse pancreatic β-cellsTamara Theiner, Noelia Jacobo-Piqueras, Dorina Tota, P. Tuluc · 2026 · Channels
- Bio-Babel: autonomous cross-language reconstruction of agent-ready computational biology ecosystemsNian-Ping Liu, Xuan-Zhi Chen, Miao Cui, Xiao-Ying Liao, Xiao-Ke Song, Sairam Pantham, Wei-Ze Xu, Xiao-Jie Qiu · 2026 · bioRxiv
- Proteomic analysis of pancreatic endocrine cells by mechanistic single-cell isolation identifies membrane pathwaysLihi Grinberg, Worood Sirhan, Marina Kurtz, Michael Assa, Assaf Malka, Shira Perez, Corine Katina, Y. Levin, R. Piran · 2026 · Experimental and Molecular Medicine
- Intra‐Islet Paracrine Regulation of Glucagon Secretion During Hypoglycemia, Euglycemia, and HyperglycemiaSAMANEH FATEHI, Jonathan V. Rocheleau, Michael Charles Riddell · 2026 · Annals of the New York Academy of Sciences
- Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cellsJ. Koepke, Wentong Long, Amy J. Barr, Peter E. Light · 2025 · Molecular Metabolism
- Amino acid sensing by the α-cell mitochondrial phosphoenolpyruvate cycle regulates intracellular Ca2+ levels without impacting glucagon secretionEr-Li Jin, Hannah R. Foster, E. Potapenko, Shih-Ming Huang, Xinhang Dong, Jing W. Hughes, M. Merrins · 2025 · bioRxiv
- FAILURE OF PANCREATIC ALPHA CELLS TO RESPOND TO HYPOGLYCEMIA IS LINKED TO IMPAIRED GLUTAMATE RECEPTOR SIGNALING IN DIABETESJ. Panzer, Alejandro Tamayo, A. Caicedo · 2021 · bioRxiv
- Sulfonylureas: Scoring beyond START STUDYAltamash Shaikh · 2017 · Indian journal of endocrinology and metabolism
- Glucagon in Islet and Metabolic RegulationDarleen A. Sandoval, Jenny Tong, David D' Alessio · 2016 · Wiley eBooks
- Matthias Braun, 23 July 1966–16 November 2013P. Rorsman, Quan Zhang · 2014 · Diabetologia
- Long noncoding RNAs are critical regulators of pancreatic islet development and functionRuth A. Singer · 2018
- Role of the type II diabetes-associated gene SLC30A8 in the pancreatic α-cellA. Solomou · 2015
- 1.グルカゴン分泌の分子機構: α 細胞内でのregulation重藤 誠 · 2012