Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets

Ramracheya, Reshma, Ward, Caroline, Shigeto, Makoto, Walker, Jonathan N., Amisten, Stefan, Zhang, Quan, Johnson, Paul R., Rorsman, Patrik +1 more·2010·Diabetes

Cited by (123)

Items 101–123 of 123

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  3. Promiscuous receptor activation mediates glucagonostatic effects of GLP-1(9-36) and GLP-1(7-36)
    C. Guida, C. Miranda, I. W. Asterholm, D. Basco, A. Benrick, Belén Chanclón, M. Chibalina, Matthew Harris, Joely A. Kellard, L. McCulloch et al. · 2019 · bioRxiv
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  5. Antidiabetic agents: Do they hit the right targets?
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  6. GABAA Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets
    S. Korol, Zhe Jin, B. Birnir · 2019 · bioRxiv
  7. Zinc Homeostasis and the Risk of Type 2 Diabetes: Complex Role of ZnT8 in Insulin and Glucagon Secretion.
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  8. Paracrine inhibition via G protein inwardly rectifying potassium channels regulates glucagon secretion from human pancreatic alpha cells
    J. Panzer, A. Lang, Noah J Levi, P. Garcia, Rene Barro-Soria, Alejandro Caicedo · 2026 · Cell Reports
  9. On the Electrophysiological Component of Pancreatic Alpha-Cell Models
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  10. Heterogenous impairment of α-cell function in type 2 diabetes is linked to cell maturation state
    Xiao-Qing Dai, J. Camunas-Soler, L. Briant, Theodore dos Santos, A. Spigelman, Emily M. Walker, R. A. Drigo, Austin Bautista, Robert C. Jones, J. Lyon et al. · 2021 · bioRxiv
  11. Postnatal refinement of CaV channel isoform composition, electrical activity, and insulin release in mouse pancreatic β-cells
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  13. Proteomic analysis of pancreatic endocrine cells by mechanistic single-cell isolation identifies membrane pathways
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  14. Intra‐Islet Paracrine Regulation of Glucagon Secretion During Hypoglycemia, Euglycemia, and Hyperglycemia
    SAMANEH FATEHI, Jonathan V. Rocheleau, Michael Charles Riddell · 2026 · Annals of the New York Academy of Sciences
  15. Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells
    J. Koepke, Wentong Long, Amy J. Barr, Peter E. Light · 2025 · Molecular Metabolism
  16. Amino acid sensing by the α-cell mitochondrial phosphoenolpyruvate cycle regulates intracellular Ca2+ levels without impacting glucagon secretion
    Er-Li Jin, Hannah R. Foster, E. Potapenko, Shih-Ming Huang, Xinhang Dong, Jing W. Hughes, M. Merrins · 2025 · bioRxiv
  17. FAILURE OF PANCREATIC ALPHA CELLS TO RESPOND TO HYPOGLYCEMIA IS LINKED TO IMPAIRED GLUTAMATE RECEPTOR SIGNALING IN DIABETES
    J. Panzer, Alejandro Tamayo, A. Caicedo · 2021 · bioRxiv
  18. Sulfonylureas: Scoring beyond START STUDY
    Altamash Shaikh · 2017 · Indian journal of endocrinology and metabolism
  19. Glucagon in Islet and Metabolic Regulation
    Darleen A. Sandoval, Jenny Tong, David D' Alessio · 2016 · Wiley eBooks
  20. Matthias Braun, 23 July 1966–16 November 2013
    P. Rorsman, Quan Zhang · 2014 · Diabetologia
  21. Long noncoding RNAs are critical regulators of pancreatic islet development and function
    Ruth A. Singer · 2018
  22. Role of the type II diabetes-associated gene SLC30A8 in the pancreatic α-cell
    A. Solomou · 2015
  23. 1.グルカゴン分泌の分子機構: α 細胞内でのregulation
    重藤 誠 · 2012