Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance

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2. Effects of raising muscle glycogen synthesis rate on skeletal muscle ATP turnover rate in type 2 diabetes
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3. Does Homeostasis Model Assessment Insulin Resistance Have a Predictive Value for Post-Coronary Artery Bypass Grafting Surgery Outcomes?
   Ebuzer Aydın, Mehmet Özkökeli · 2014 · Brazilian Journal of Cardiovascular Surgery
4. Mitochondrial Utilization of Competing Fuels Is Altered in Insulin Resistant Skeletal Muscle of Non-obese Rats (Goto-Kakizaki)
   Nicola Lai, Ciarán E. Fealy, Chinna Kummitha, Silvia Cabras, John P. Kirwan, Charles L. Hoppel · 2020 · Frontiers in Physiology
5. Invasive and noninvasive markers of human skeletal muscle mitochondrial function
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6. Insulin resistance after a 3-day fast is associated with an increased capacity of skeletal muscle to oxidize lipids
   Sarah Joan Blackwood, Oscar Horwath, Marcus Moberg, Marjan Pontén, William Apró, Maria Ekblom, Filip Jon Larsen, Abram Katz · 2023 · American Journal of Physiology-Endocrinology and Metabolism
7. A Comprehensive Perspective on the Biological Effects of Intermittent Fasting and Periodic Short-Term Fasting: A Promising Strategy for Optimizing Metabolic Health
   Barbara Ruszkowska-Ciastek, Karolina Kapłon, Przemysław Domaszewski · 2025 · Nutrients
8. Increasing whole-body energetic stress does not augment fasting-induced changes in human skeletal muscle
   Hashim Islam, Alessandra Amato, Jacob T. Bonafiglia, Fasih Ahmad Rahman, Nicholas Preobrazenski, Andrew Ma, Craig A. Simpson, Joe Quadrilatero, Brendon J. Gurd · 2021 · Pflügers Archiv - European Journal of Physiology
9. Glucose and lipid metabolism alterations in liver and adipose tissue pre-dispose p47phox knockout mice to systemic insulin resistance
   Babunageswararao Kanuri, Sanjay C. Rebello, Priya Pathak, Hobby Aggarwal, Jitendra Singh Kanshana, Deepika Awasthi, Anand P. Gupta, Jiaur Rahaman Gayen, Kumaravelu Jagavelu, Madhu Dikshit · 2018 · Free Radical Research
10. Intermittent fasting reduces mouse body fat while maintaining muscle mass by regulating protein synthesis and autophagy
    Rikako Yoshii, Kazuhiko Higashida, Naoya Nakai · 2023 · Nutrition
11. The impact of a 48-h fast on SIRT1 and GCN5 in human skeletal muscle
    Brittany A. Edgett, Trisha D. Scribbans, James P. Raleigh, Jennifer B. L. Matusiak, Kristen M. Boonstra, Craig A. Simpson, Christopher G. R. Perry, Joe Quadrilatero, Brendon J. Gurd · 2016 · Applied Physiology, Nutrition, and Metabolism
12. Silymarin: A Natural Compound for Obesity Management
    Jéssica Alves de Freitas, Aline Boveto Santamarina, José Pinhata Otoch, Ana Flávia Marçal Pessoa · 2024 · Obesities
13. Relationship of C5L2 Receptor to Skeletal Muscle Substrate Utilization
    Christian Roy, Sabina Paglialunga, Gert Schaart, Esther Moonen‐Kornips, Ruth C. R. Meex, Esther Phielix E, Joris Hoeks J, Matthijs K. C. Hesselink, Katherine Cianflone, Patrick Schrauwen · 2013 · PLoS ONE
14. Fasting Mimicking Diet for Metabolic Syndrome: A Narrative Review of Human Studies
    Alina Delia Popa, Andreea Gherasim, Laura Mihalache, Lidia Iuliana Arhire, Mariana Graur, Otilia Niță · 2025 · Metabolites
15. Mitochondrial Metabolism and Insulin Action
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16. Postexercise changes in myocellular lipid droplet characteristics of young lean individuals are affected by circulatory nonesterified fatty acids
    Sabine Daemen, Nynke van Polanen, Lena Bilet, Esther Phielix E, Esther Moonen‐Kornips, Vera B. Schrauwen‐Hinderling, Patrick Schrauwen, Matthijs K. C. Hesselink · 2021 · American Journal of Physiology-Endocrinology and Metabolism
17. Treating Diabetes with Exercise – Focus on the Microvasculature
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18. Fructose-rich diet differently affects angiotensin II receptor content in the nucleus and a plasma membrane fraction of visceral adipose tissue
    Maja Bundalo, Ana D. Djordjevic, Biljana N. Bursać, Maja Živković, Goran Korićanac, Aleksandra Stanković · 2017 · Applied Physiology, Nutrition, and Metabolism
19. Variability in HOMA‐IR, Lipoprotein Profile and Selected Hormones in Young Active Men
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20. Altered immunometabolic response to fasting in humans living with obesity
    Helena Neudorf, Roderick E. Sandilands, Spencer Ursel, Hillary Shaba, Darren Barg, Takeshi Tsusaka, María Dolores Moya-Garzón, Erica M. Vaz, Patricia Schimweg, Emily L. Goldberg et al. · 2025 · iScience
21. A prolonged fast improves overnight substrate oxidation without modulating hepatic glycogen in adults with and without nonalcoholic fatty liver: A randomized crossover trial
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22. Physiopathologie de l’insulinorésistance dans le muscle squelettique et implication des fonctions mitochondriales
    Valentin Barquissau, Béatrice Morio · 2011 · Nutrition Clinique et Métabolisme
23. Causes of Fasting-Evoked en Route Hypoglycemia in Diabetes (FEEHD): A Case Series Study
    Saleh A. Aldasouqi, Ved Vyas Gossain, Matthew Hebdon, Archana Reddy, José Goldman, Sameer Ansar, Bhavini Bhavsar · 2012 · International Journal of Clinical Medicine
24. Fasting for haemostasis in children with gastrointestinal bleeding
    Shuanghong Luo, Qin Guo, Guan Jian Liu, Chaomin Wan · 2016 · Cochrane Database of Systematic Reviews
25. Starvation
    Charles Weissman, Rawhi Hashem · 2020 · Springer eBooks
26. Insulin resistance in the 21st century: new takes on an old problem—2025 Diabetes, Diabetes Care, and Diabetologia Expert Forum
    Amalia Gastaldelli, Eunhee Choi, Karin Conde‐Knape, Olga Göransson, Anna Krook, Sanna H. Lehtonen, Michael Roden, Patrick Schrauwen, Lauren Marie Sparks, Martin Heni · 2026 · Diabetologia
27. Muscle Biopsy to Investigate Mitochondrial Turnover
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28. Muscle Biopsy To Investigate Mitochondrial Turnover
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29. Promoting healthy ageing
    Niels J. Connell · 2021
30. Cardiomyopathy and muscle insulin resistance in type 2 diabetes : craving for sugars, or dying for fat?
    Tineke van de Weijer · 2013
31. Mitochondria, lipotoxicity and skeletal muscle metabolism : implications for type 2 diabetes mellitus
    Bianca W. J. van Bree · 2014
32. Causes and consequences of lipid overload in skeletal muscle, liver and heart
    Lena Bilet · 2015
33. Effects of Exercise and Elevated Fatty Acid Availability on Muscle Lipid Metabolism and Insulin Sensitivity.
    Sean Alec Newsom · 2012
34. The role of free fatty acids in ectopic lipid accumulation, insulin resistance and inflammation in humans.
    Noud A. van Herpen · 2012
35. Cold and diet induced thermogenesis in humans; Implications for obesity
    Sander L. J. Wijers · 2011
36. Exercise strategies to improve aerobic capacity, insulin sensitivity and mitochondrial biogenesis
    Per Frank · 2014 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
37. Does Homeostasis Model Assessment of Insulin Resistance have a predictive value for post-coronary artery bypass grafting surgery outcomes? O Modelo de Avaliação da Homeostase da Resistência à Insulina tem valor preditivo para os resultados após a cirurgia de revascularização miocárdica?
    Ebuzer Aydın, Mehmet Özkökeli · 2014
38. THE EFFECT OF CONTRACTILE ACTIVITY AND SUBSTRATE CHALLENGES ON METABOLIC FLEXIBILITY IN HUMAN PRIMARY MYOTUBES
    Todd M. Weber · 2013 · The Scholarship East Carolina University's Institutional Repository (East Carolina University)
39. Dietary polyphenols: modulators of energy and substrate metabolism in obese humans
    Jasper Most · 2016
40. Regulation of SIRT1, SIRT3, PGC-1α, and LRP130 in Response to Energetic Stress in Human Skeletal Muscle
    Brittany A. Edgett · 2017 · QSpace (Queen's University Library)
41. Myocellular lipid droplets and insulin sensitivity: a microscopy approach
    A. Gemmink · 2017
42. Over een zoete ziekte en vette jaren
    Schrauwen · 2011
43. Skeletal muscle health in aging
    Lotte Grevendonk · 2021
44. Novel aspects of exercise training to promote human metabolic health
    Rodrigo Mancilla · 2022
45. Insulinorésistance et mitochondries
    2010 · Médecine des Maladies Métaboliques
46. Fasting for haemostasis in children with gastrointestinal bleeding
    Shuanghong Luo, Qin Guo, Guan Jian Liu, Chaomin Wan · 2013 · Cochrane Database of Systematic Reviews
47. Human brown adipose tissue
    Michael Petrus Bernardus Moonen · 2021
48. Starvation
    Charles Weissman, Rawhi Hashem · 2014 · Springer eBooks
49. Improving flexibility in substrate metabolism
    Anna Veelen · 2022
50. A metabolically healthy lifestyle
    Charlotte Andriessen · 2023
51. Insulin Resistance in Multiple Organs and Systems
    Luís Jesuíno de Oliveira Andrade, Gabriela Correia Matos de Oliveira, Alcina Maria Vinhaes Bittencourt, Luís Matos de Oliveira · 2023 · Research Square
52. A 24-hour perspective on insulin resistance
    Jan‐Frieder Harmsen · 2023
53. An exercise-modifiable mitochondrial basis for skeletal muscle insulin resistance in humans
    T P. Nielsen, Michelle Damgaard, Nicoline R. Andersen, Morten Dunø, Anja Lisbeth Frederiksen, Gerrit van Hall, Lykke Sylow, Marta Murgia, Steen Larsen, Signe S. Torekov et al. · 2025 · medRxiv
54. Ramadan fasting is associated with changes in skeletal muscle volume and lipid content, and markers of metabolic health, in healthy males and females
    Ashwag Alarfaj, G. Whelehan, Fatma Sabet, J. Fulford, B. Wall, F. Stephens · 2026 · The Journal of Nutritional Physiology
55. Fasting‐induced glucose intolerance is not impacted by the addition of daily exercise: A randomized crossover study
    Tori Bouck, Alexis Marcotte‐Chénard, Darren Barg, Charlie Kanuka, Roderick E. Sandilands, Spencer Ursel, Garett Jackson, Arwyn MacIntosh, Sean McIntyre, Sriyashika Nekkanti et al. · 2026 · The Journal of Physiology
56. Electrical Pulse Stimulation Partially Restores Insulin Signaling in Palmitate‐Induced Insulin‐Resistant Skeletal Muscle Cells via Mitochondrial Remodeling and Contractile Activity‐Dependent Secretome
    Alessandro Falcone, Sevgican Demir, Mona Hendlinger, Patrick Schrauwen, Polina Lipaeva, Marlene Piribauer, Geronimo Heilmann, Sandra Trenkamp, Michael Roden, Lucia Mastrototaro · 2026 · Journal of Cellular Physiology