Efficacy of metreleptin in obese patients with type 2 diabetes: Cellular and molecular pathways underlying leptin tolerance

Moon, Hyun-Seuk, Matarese, Giuseppe, Brennan, Aoife M., Chamberland, John P., Liu, Xiaowen, Fiorenza, Christina G., Mylvaganam, Geetha H., Abanni, Luisa +5 more·2011·Diabetes
DOI 10.2337/db10-1791

Cited by (151)

Items 101–151 of 151

  1. Correlation of Leptin in Patients With Type 2 Diabetes Mellitus
    Kajol Manglani, Nabila Nowshin Anika, Dhriti Patel, Sharan Jhaveri, Chaithanya Avanthika, Sourav Sudan, Zainab Alimohamed, Kripa Tiwari · 2024 · Cureus
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    Thomas Scherer, Hendrik Lehnert, Manfred Hallschmid · 2013 · Endocrinology and Metabolism Clinics of North America
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    Ayse Sahin-Efe, Stergios A. Pοlyzos, Fadime Dincer, Lesya Zaichenko, Rosemary McGovern, Benjamin E. Schneider, Christos Socrates Mantzoros · 2015 · Metabolism
  4. Gut-Brain Endocrine Axes in Weight Regulation and Obesity Pharmacotherapy
    Dante J. Merlino, Erik Scott Blomain, Amanda Aing, Scott Arthur Waldman · 2014 · Journal of Clinical Medicine
  5. Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
    Xuemin Peng, Jiaojiao Huang, Huajie Zou, Bei Peng, San-Shan Xia, Kun Dong, Nan Sun, Jing Tao, Yan Yang · 2022 · Lipids in Health and Disease
  6. UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia
    Petr Zouhar, Günaj Rakipovski, Muhammad Hamza Bokhari, Oliver Busby, Johan F. Paulsson, Kilian W. Conde‐Frieboes, Johannes Josef Fels, Kirsten Raun, Birgitte Andersen, Barbara Cannon et al. · 2019 · American Journal of Physiology-Endocrinology and Metabolism
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    Miklós Rohla, Thomas Werner Weiss · 2014 · Clinical Lipidology
  8. Astragalus mongholicus powder, a traditional Chinese medicine formula ameliorate type 2 diabetes by regulating adipoinsular axis in diabetic mice
    Siyuan Xu, Bixian Ye, Jinlei Li, Yonghui Dou, Yuying Yu, Yifan Feng, Lexun Wang, David Chi‐Cheong Wan, Xianglu Rong · 2022 · Frontiers in Pharmacology
  9. Sleep apnea in relation to metabolism: An urgent need to study underlying mechanisms and to develop novel treatments for this unmet clinical need
    Olivia M. Farr, Christos Socrates Mantzoros · 2017 · Metabolism
  10. Leptin and Obesity
    Yuanyuan Zhang, Jun Tao Ren · 2015 · Springer eBooks
  11. Plasma leptin level mirrors metabolome alterations in young adults
    Ashok Kumar, Gopika Satheesh, Gadadharan Vijayakumar, Mahesh Chandran, Priya Ramesh Prabhu, Leena Simon, Vellappillil Raman Kutty, C. Sudha Kartha, Abdul Jaleel · 2020 · Metabolomics
  12. Regulation of feeding and therapeutic application of bioactive peptides
    Hiroaki Ueno, Weidong Zhang, Masamitsu Nakazato · 2022 · Pharmacology & Therapeutics
  13. Metreleptin treatment of non-HIV lipodystrophy syndromes
    Benjamin Chevalier, Madleen Lemaître, Lysiane Leguier, Kristell Le Mapihan, Claire Douillard, Arnaud Jannin, Stéphanie Espiard, Marie‐Christine Vantyghem · 2021 · La Presse Médicale
  14. Antiobesity Pharmacotherapy for Patients With Genetic Obesity Due to Defects in the Leptin-Melanocortin Pathway
    Mila Sofie Welling, Elisabeth F. C. van Rossum, Erica L T van den Akker · 2025 · Endocrine Reviews
  15. Effects of Angiotensin Receptor-Neprilysin Inhibitors (ARNIs) on the Glucose and Fat Metabolism Biomarkers Leptin and Fructosamine
    Bernhard Ohnewein, Zornitsa Shomanova, Vera Paar, Albert Topf, Peter Jirak, Lukas Fiedler, Christina Granitz, Vincent F. van Almsick, Dilvin Semo, Naufal Sh. Zagidullin et al. · 2023 · Journal of Clinical Medicine
  16. Unveiling the intricate dance: Obesity and TNBC connection examined
    Patrick A. Newport‐Ratiu, Kamel Abou Hussein, Teralyn Carter, Shoghag B. Panjarian, Subash C. Jonnalagadda, Manoj Kumar Pandey · 2024 · Life Sciences
  17. Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings
    Rushika Conroy, Gerardo Febres, Donald J. McMahon, Michael O. Thorner, Bruce D. Gaylinn, Irene M. Conwell, Louis J. Aronne, Judith Körner · 2014 · International Journal of Endocrinology
  18. Onset of leptin resistance shows temporal differences related to dose or pulsed treatment
    Kevin Y. E. Strehler, Michael Edwin Matheny, Nataliya Kirichenko, Yasemin Sakarya, Erin B. Bruce, Hale Zerrin Toklu, Christy S. Carter, Drake Morgan, Nihal Tümer, Philip J. Scarpace · 2016 · European Journal of Pharmacology
  19. Adipokines and Metabolism
    Rexford S. Ahima, Laura M. Scolaro, Hyeong-Kyu Park · 2016 · Springer eBooks
  20. The Central Question of Type 2 Diabetes
    Thaïs Rouquet, Marion S. Bonnet, Pierre Clément, Michel Dallaporta, Jean‐Denis Troadec, Julien Roux, Bruno Bariohay · 2013 · Pharmaceutical Patent Analyst
  21. The Influence of Polypharmacy on Nutrition
    Korinne Piccolo, Joseph I. Boullata · 2015 · Springer eBooks
  22. Leptin for Obesity: Previous Failures, Promising Future
    A Marcucci, Jamie Ann Mullally, William H. Frishman · 2025 · Cardiology in Review
  23. Impact of weight loss on obese children and adolescents with asthma: a systematic review and meta-analysis
    Yucan Deng, Jinfeng Zhao, Runfang Tian, Li Liu, Zhiguang Ping · 2026 · Journal of Asthma
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  25. Adipokines and Metabolism
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    Cláudia Matta-Coelho, Rachel Agius, James D. Crane, Barbara M. McGowan · 2021 · British Journal of Diabetes
  27. High-Amylose Maize Resistant Starch Type 2 (HAM-RS2) Intake, Body Composition, and Satiety in Overweight Adults
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  28. The Future of Diabetes
    Zachary T. Bloomgarden · 2015 · Canadian Journal of Diabetes
  29. Les traitements médicamenteux de l’obésité
    Claire Rives‐Lange, Amel Ait Boudaoud, Sébastien Czernichow, Claire Carette · 2017 · Acta Endoscopica
  30. The Influence of Leptin Resistance on the Development of Childhood Obesity
    Stanley Cho, Hunter Batchelder · 2023 · Journal of Student Research
  31. Adipokines and Metabolism
    Rexford S. Ahima, Hyeong Kyu Park · 2023 · Springer eBooks
  32. The Effects of Omega 3 Supplementation on Markers of Obesity and Endothelial Function in Healthy Subjects
    Samer Alanbagy · 2014
  33. Evaluation of a Medication Therapy Management Program in Medicare Beneficiaries at High Risk of Adverse Drug Events: Study Methods -- Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 4: Technology and Medication Safety)
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  34. The Biology of Adipose Tissue
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  36. The metabolic effects of leptin therapy and glucagon suppression therapy in mouse models of diabetes
    Neumann, Ursula Hope · 2017 · cIRcle (University of British Columbia)
  37. Ожиріння в дітей: визначення, лікування, профілактика. Клінічні практичні настанови Ендокринологічного Товариства. Частина 2
    Н. Б. Зелінська · 2018 · The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy
  38. Advances in Pharmacological Treatment of Pediatric Obesity
    Michael I. Goran · 2016 · CRC Press eBooks
  39. The Future of Diabetes
    Mariela Glandt, Zachary T. Bloomgarden · 2016 · Springer eBooks
  40. The Future of Diabetes
    Mariela Glandt, Zachary T. Bloomgarden · 2017 · Springer eBooks
  41. Adipokines and Metabolism
    Rexford S. Ahima, Laura M. Scolaro, Hyeong-Kyu Park · 2017 · Springer eBooks
  42. Adipokines and Metabolism
    Rexford S. Ahima, Hyeong Kyu Park · 2023 · Springer eBooks
  43. Additional file 1 of Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
    Peng, Xuemin, Huang, Jiaojiao, Zou, Huajie, Peng, Bei, Xia, Sanshan, Kun Dong, Sun, Nan, Tao, Jing, Yan Yang · 2022 · Figshare
  44. Additional file 3 of Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
    Peng, Xuemin, Huang, Jiaojiao, Zou, Huajie, Peng, Bei, Xia, Sanshan, Kun Dong, Sun, Nan, Tao, Jing, Yan Yang · 2022 · Figshare
  45. Additional file 2 of Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
    Peng, Xuemin, Huang, Jiaojiao, Zou, Huajie, Peng, Bei, Xia, Sanshan, Kun Dong, Sun, Nan, Tao, Jing, Yan Yang · 2022 · Figshare
  46. Anti-obesity Pharmacotherapy for Patients with Genetic Obesity Disorders
    Mila Sofie Welling, Elisabeth F. C. van Rossum, Erica van den Akker · 2025 · Springer eBooks
  47. Implication des neurones exprimant NUCB2/nesfatine-1 dans la régulation de l'homéostasie énergétique
    Marion S. Bonnet · 2013 · theses.fr (ABES)
  48. Traitement par leptine recombinante dans les syndromes lipodystrophiques génétiques : effets sur le métabolisme glucido-lipidique
    Camille Vatier · 2017 · theses.fr (ABES)
  49. Lipodystrophie partielle familiale de type 2 – description phénotypique et étude des paramètres d'insulino-résistance et d'inflammation dans une population atteinte du variant pathogène p.(Thr655Asnfs*49).
    Guillaume Treiber · 2023
  50. Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models
    Valeria Pellegrini, Rosalba La Grotta, Alessia Metallo, Francesco Prattichizzo, Chiara Frigé, Giulia Matacchione, Angelica Giuliani, Jacopo Sabbatinelli, Fabiola Olivieri, Francesca Rispoli et al. · 2026 · MedComm
  51. Leptin Resistance and Endoplasmic Reticulum Stress: ER Proteostasis as a Proposed Convergence Node—A Mechanistic Synthesis of Preclinical Evidence
    Şule Arslan, Nida Yıldız, Halit Tanju Besler · 2026 · Life