Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

Zheng, Hongting, Whitman, Samantha A., Wu, Wei, Wondrak, Georg T., Wong, Pak K., Fang, Deyu, Zhang, Donna D.·2011·Diabetes

Cited by (507)

Items 301–400 of 507

  1. Sulforaphane Prevents Angiotensin II‐Induced Testicular Cell Death via Activation of NRF2
    Yonggang Wang, Hao Wu, Ying Xin, Yang Bai, Lili Kong, Yi Tan, Feng Liu, Lu Cai · 2017 · Oxidative Medicine and Cellular Longevity
  2. Salvia miltiorrhizaLipophilic Fraction Attenuates Oxidative Stress in Diabetic Nephropathy through Activation of Nuclear Factor Erythroid 2-Related Factor 2
    Lin Kun An, Mei Zhou, Faiz M. M. T. Marikar, Xuewen Hu, Qiu-Yun Miao, Ping Li, Jun Chen · 2017 · The American Journal of Chinese Medicine
  3. Potential drugs which activate nuclear factor E2-related factor 2 signaling to prevent diabetic cardiovascular complications: A focus on fumaric acid esters
    Shanshan Zhou, Jingpeng Jin, Tao Bai, Leroy R. Sachleben, Lu Cai, Yang Zheng · 2015 · Life Sciences
  4. Naturally-derived modulators of the Nrf2 pathway and their roles in the intervention of diseases
    Tian Wang, Mingjie Liu, Xinyu Li, Sen Zhang, Haoran Gu, Xuan Wei, Xiaoning Wang, Zhen‐Peng Xu, Tao Shen · 2024 · Free Radical Biology and Medicine
  5. Protective effect of a hydrogen sulfide donor on balloon injury-induced restenosis via the Nrf2/HIF-1α signaling pathway
    Ken Ling, Ancong Xu, Yunfei Chen, Xueyin Chen, Yiqing Li, Weici Wang · 2019 · International Journal of Molecular Medicine
  6. Activation of Nrf2 attenuates delayed gastric emptying in obesity induced diabetic (T2DM) female mice
    Chethan Sampath, Jeremy C. Sprouse, Michael L. Freeman, Pandu R. Gangula · 2019 · Free Radical Biology and Medicine
  7. miR-98-5p Alleviated Epithelial-to-Mesenchymal Transition and Renal Fibrosis via Targeting Hmga2 in Diabetic Nephropathy
    Yingchun Zhu, Xu Jiang, Wenxing Liang, Ji Li, Linhong Feng, Pengxi Zheng, Tingting Ji, Shoujun Bai · 2019 · International Journal of Endocrinology
  8. The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase α
    Daiki Hayashi, Liuqing Wang, Shuji Ueda, Minoru Yamanoue, Hitoshi Ashida, Yasuhito Shirai · 2020 · Scientific Reports
  9. Proanthocyanidins Protect Against Cadmium-Induced Diabetic Nephropathy Through p38 MAPK and Keap1/Nrf2 Signaling Pathways
    Pin Gong, Peipei Wang, Sihui Pi, Yuxi Guo, Shuya Pei, Wenjuan Yang, Xiangna Chang, Lan Wang, Fuxin Chen · 2022 · Frontiers in Pharmacology
  10. NRF2 and NF-κB mRNA expression in chronic kidney disease: a focus on nondialysis patients
    Viviane de Oliveira Leal, Juliana F. Saldanha, Milena Barcza Stockler‐Pinto, L. Cardozo, Felipe R. Santos, Alex S. D. Albuquerque, Maurilo Leite, Denise Mafra · 2015 · International Urology and Nephrology
  11. Sulforaphane protects rabbit corneas against oxidative stress injury in keratoconus through activation of the Nrf-2/HO-1 antioxidant pathway
    Ruixing Liu, Xiaoming Yan · 2018 · International Journal of Molecular Medicine
  12. Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor
    Michael John Kerins, Pengfei Liu, Wang Tian, William Mannheim, Donna D. Zhang, Aikseng Ooi · 2019 · Molecular and Cellular Biology
  13. USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells
    Kaipeng Huang, Xilin Zhao · 2020 · Experimental Cell Research
  14. Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities
    Ara Aboolian, Sofia Urner, Michael Roden, Jay C. Jha, Karin Agnes Maria Jandeleit-Dahm · 2022 · Handbook of experimental pharmacology
  15. The roles of hydrogen sulfide in renal physiology and disease states
    Jianan Feng, Xiangxue Lu, Han Li, Shixiang Wang · 2022 · Renal Failure
  16. Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways
    Jiayu Shen, Zhuo Tong, Bing Han, Ziyin Zhang, Zudan Xian, Yuan Yao, Xinliang Duan, Sichen Han, Peng Liu, Zilin Wang · 2025 · International Journal of Nanomedicine
  17. Efficacy of Zingiber officinale and Cinnamomum zeylanicum extracts against experimental Trichinella spiralis infection
    Marwa Ahmed Mohamed Salama, Nahed E. Mostafa, Naglaa Fathy Abd El-Aal, Howayda Said Fouad Moawad, Samar Kamel Hammad, Rasha Adel, Eman Mostafa · 2021 · Journal of Parasitic Diseases
  18. Influence of zinc levels and Nrf2 expression in the clinical and pathological changes in patients with diabetic nephropathy
    Ping Nie, Yan Lou, Xue Bai, Yuexin Zhu, Qiaoyan Guo, Ping Luo, Weiguang Zhang, Bing Li · 2022 · Nutrition and Diabetes
  19. Sulforaphane exhibits potent renoprotective effects in preclinical models of kidney diseases: A systematic review and meta-analysis
    Elisa Bernardes Monteiro, Matheus Ajackson, Milena Barcza Stockler‐Pinto, Fitsum Guebre‐Egziabher, Júlio Beltrame Daleprane, Christophe Olivier Soulage · 2023 · Life Sciences
  20. Nonpharmacologic Strategies to Modulate Nuclear Factor Erythroid 2–related Factor 2 Pathway in Chronic Kidney Disease
    Marta Esgalhado, Peter Stenvinkel, Denise Mafra · 2017 · Journal of Renal Nutrition
  21. Far-red light-activated human islet-like designer cells enable sustained fine-tuned secretion of insulin for glucose control
    Guiling Yu, Mingliang Zhang, Ling Gao, Yang Zhou, Longliang Qiao, Jianli Yin, Yiwen Wang, Jian Zhou, Haifeng Ye · 2021 · Molecular Therapy
  22. Mechanistic role of antioxidants in rescuing delayed gastric emptying in high fat diet induced diabetic female mice
    Chethan Sampath, Derek M. Wilus, Mohammad Tabatabai, Michael L. Freeman, Pandu R. Gangula · 2021 · Biomedicine & Pharmacotherapy
  23. The Therapeutic Activities of Metformin: Focus on the Nrf2 Signaling Pathway and Oxidative Stress Amelioration
    Gholamreza Bazmandegan, Mohammad Yasin Zamanian, Lydia Giménez‐Llort, Marjan Nikbakhtzadeh, Zahra Kamiab, Mahsa Heidari · 2022 · Current Molecular Pharmacology
  24. Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy
    Yawei Bian, Chonglin Shi, Shan Song, Lin Mu, Ming Ting Wu, Duojun Qiu, Jiajia Dong, Wei Zhang, Chen Yuan, Dongyun Wang et al. · 2022 · Cell and Tissue Research
  25. Neurotoxic effects of iron overload under high glucose concentration.
    Shi Zhao, Lin Zhang, Zihui Xu, Weiqun Chen · 2013 · PubMed Central
  26. Bardoxolone methyl modulates efflux transporter and detoxifying enzyme expression in cisplatin-induced kidney cell injury
    Amandla Atilano‐Roque, Lauren M. Aleksunes, Melanie S. Joy · 2016 · Toxicology Letters
  27. Prevention of Streptozotocin‐Induced Diabetic Nephropathy by MG132: Possible Roles of Nrf2 and IκB
    Lili Kong, Yangwei Wang, Manyu Luo, Yi Tan, Wenpeng Cui, Lining Miao · 2017 · Oxidative Medicine and Cellular Longevity
  28. Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease
    Mei Jing, Yun Cen, Fangfang Gao, Ting Wang, Jinxin Jiang, Qianqian Jian, Liangmiao Wu, Baojian Guo, Fangcheng Luo, Gaoxiao Zhang et al. · 2021 · Frontiers in Pharmacology
  29. Recent Advances in KEAP1/NRF2 -Targeting Strategies by Phytochemical Antioxidants, Nanoparticles, and Biocompatible Scaffolds for the Treatment of Diabetic Cardiovascular Complications
    Andrea Rampin, Michele Carrabba, Martina Mutoli, Charlotte L. Eman, Gianluca Testa, Paolo Roberto Madeddu, Gaia Spinetti · 2022 · Antioxidants and Redox Signaling
  30. NRF2 pathway activation attenuates ageing-related renal phenotypes due to α-klotho deficiency
    Mingyue Zhao, Shohei Murakami, Daisuke Matsumaru, Takeshi Kawauchi, Yo‐ichi Nabeshima, Hozumi Motohashi · 2022 · The Journal of Biochemistry
  31. Immune response gene 1 deficiency impairs Nrf2 activation and aggravates liver fibrosis in mice
    Kerui Fan, Xinyan Zan, Ying Zhi, Yongqiang Yang, Kai Hu, Xinyue Zhang, Xue Zhang, Shuang Zhao, Kun Chen, Xianqiong Gong et al. · 2022 · Biochemical and Biophysical Research Communications
  32. Novel Therapies for Diabetic Kidney Disease: Storied Past and Forward Paths
    Brad P. Dieter, Radica Z. Alicic, Rick L. Meek, Robert J. Anderberg, Sheryl K. Cooney, Katherine R. Tuttle · 2015 · Diabetes Spectrum
  33. DNA Methylome and Transcriptome Alterations in High Glucose-Induced Diabetic Nephropathy Cellular Model and Identification of Novel Targets for Treatment by Tanshinone IIA
    Wenji Li, Davit Sargsyan, Renyi Wu, Shanyi N. Li, Lujing Wang, David Cheng, Ah‐Ng Tony Kong · 2019 · Chemical Research in Toxicology
  34. Simultaneous determination of cinnamaldehyde and its metabolite in rat tissues by gas chromatography–mass spectrometry
    Hang Zhao, Qian Yang, Yanhua Xie, Jiyuan Sun, Honghai Tu, Wei Cao, Siwang Wang · 2014 · Biomedical Chromatography
  35. Transient Receptor Potential Ankyrin Type-1 Channels as a Potential Target for the Treatment of Cardiovascular Diseases
    Song Gao, Keneilwe Kenny Kaudimba, Shanshan Guo, Shuang Zhang, Tiemin Liu, Peijie Chen, Ru Wang · 2020 · Frontiers in Physiology
  36. Urolithin A ameliorates diabetic retinopathy via activation of the Nrf2/HO-1 pathway
    Zepeng Xu, Songtao Li, Kunmeng Li, Xiaoyu Wang, Xiaojie Li, Meixia An, Xiaoyi Yu, Xinguang Long, Ruiying Zhong, Qiuhong Liu et al. · 2022 · Endocrine Journal
  37. An update on molecular mechanisms of curcumin effect on diabetes
    Wensong Lu, Fedora Khatibi Shahidi, Khatereh Khorsandi, Reza Hosseinzadeh, Asma Gul, Veronica Balick · 2022 · Journal of Food Biochemistry
  38. Protective effect of eriodictyol against hyperglycemia-induced diabetic nephropathy in rats entails antioxidant and anti-inflammatory effects mediated by activating Nrf2
    Jozaa Zaidan ALTAMIMI, Nora A. AlFaris, Ghedeir Muslem Alshammari, Reham I. Alagal, Dalal Hamad ALJABRYN, Mohammed Abdo Yahya · 2023 · Saudi Pharmaceutical Journal
  39. Formononetin, a bioactive isoflavonoid constituent from Astragalus membranaceus (Fisch.) Bunge, ameliorates type 1 diabetes mellitus via activation of Keap1/Nrf2 signaling pathway: An integrated study supported by network pharmacology and experimental validation
    Haipeng Chen, Yanmei Lou, Senyi Lin, Xuanjing Tan, Yuting Zheng, Yu Hong, Ruidi Jiang, Yijie Wei, Huijie Huang, Xiaoxiao Qi et al. · 2023 · Journal of Ethnopharmacology
  40. Osthole ameliorates early diabetic kidney damage by suppressing oxidative stress, inflammation and inhibiting TGF-β1/Smads signaling pathway
    Qiangsheng Li, Yifei Wang, Jia Yan, Ruyan Yuan, Jiamin Zhang, Xinhao Guo, Mingming Zhao, Fenfen Li, Xiaotian Li · 2024 · International Immunopharmacology
  41. Glycine increases glyoxalase‐1 function by promoting nuclear factor erythroid 2‐related factor 2 translocation into the nucleus of kidney cells of streptozotocin‐induced diabetic rats
    Ziwei Wang, Dan Zhao, Lei Chen, Jingjing Li, Geheng Yuan, Guosheng Yang, Hong Zhang, Xiaohui Guo, Junqing Zhang · 2019 · Journal of Diabetes Investigation
  42. Cinnamaldehyde Supplementation Reverts Endothelial Dysfunction in Rat Models of Diet-Induced Obesity: Role of NF-E2-Related Factor-2
    Cristina Maria Sena, Ana Marta Pereira, Raquel Maria Fino Seiça · 2022 · Antioxidants
  43. Key pathways in renal disease progression of experimental diabetes: Figure 1:
    Carla Zoja, Cristina Zanchi, Ariela Benigni · 2015 · Nephrology Dialysis Transplantation
  44. Nrf2 in Type 2 diabetes and diabetic complications: Yin and Yang
    Jingqi Fu, Yongyong Hou, Peng Xue, Huihui Wang, Yuanyuan Xu, Weidong Qu, Qiang Zhang, Jingbo Pi · 2016 · Current Opinion in Toxicology
  45. Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy
    Yuki Yoshizaki, Takayasu Mori, Mari Ishigami‐Yuasa, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Naohiro Nomura, Yutaro Mori, Yuya Araki, Fumiaki Ando et al. · 2017 · Scientific Reports
  46. 3′-O-β-d-glucopyranosyl-α,4,2′,4′,6′-pentahydroxy-dihydrochalcone, from Bark of Eysenhardtia polystachya Prevents Diabetic Nephropathy via Inhibiting Protein Glycation in STZ-Nicotinamide Induced Diabetic Mice
    Rosa Perez Gutierrez, Abraham Heriberto Garcia-Campoy, Silvia Patricia Paredes-Carrera, Alethia Muñiz-Ramírez, José Mota Flores, Sergio O. Flores-Valle · 2019 · Molecules
  47. Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice
    Meiyu Chang, Guangcui Xu, Cheng Xiong, Xuesi Yang, Sensen Yan, Yingjun Tao, Haibin Li, Yuchun Li, Sanqiao Yao, Yingzheng Zhao · 2021 · Toxicology Letters
  48. Sulforaphane improves voiding function via the preserving mitochondrial function in diabetic rats
    Chia-Fa Lin, Tsung-Hung Chueh, Cheng-Hsun Chung, Shue-Dong Chung, Tzu-Ching Chang, Chiang‐Ting Chien · 2019 · Journal of the Formosan Medical Association
  49. Emerging Biomarkers and Innovative Therapeutic Strategies in Diabetic Kidney Disease: A Pathway to Precision Medicine
    Sahana Shetty, Renuka Suvarna, Avivar Awasthi, Mohan Varadanayakanahalli Bhojaraja, Joseph M Pappachan · 2025 · Diagnostics
  50. Sulforaphane ameliorates high-fat diet-induced spermatogenic deficiency in mice†
    Mu Yang, Tailang Yin, Xiao-xuan Huang, Xue Hu, Lu Yin, Jing Yang · 2019 · Biology of Reproduction
  51. Nrf2 attenuates hyperglycemia-induced nNOS impairment in adult mouse primary enteric neuronal crest cells and normalizes stomach function
    Chethan Sampath, Abhinav V. Raju, Michael L. Freeman, Shanthi Srinivasan, Pandu R. Gangula · 2022 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  52. 1,2,3,4,6‑penta‑O‑galloyl‑β‑D‑glucose alleviates inflammation and oxidative stress in diabetic nephropathy rats through MAPK/NF‑κB and ERK/Nrf2/HO‑1 signaling pathways
    Dong Wang, Yan Li, Liheng Dai, Yanxia Wang, Congna Zhao, Wangang Wang, Yu Zhang, Yinrui Zhao, Tingting Yu · 2022 · Experimental and Therapeutic Medicine
  53. Histone Lysine Methylation in TGF-β1 Mediated p21 Gene Expression in Rat Mesangial Cells
    Qiaoyan Guo, Xiaoxia Li, Hongbo Han, Chaoyuan Li, Shujun Liu, Wenhui Gao, Guangdong Sun · 2016 · BioMed Research International
  54. Polydatin protects Schwann cells from methylglyoxal induced cytotoxicity and promotes crushed sciatic nerves regeneration of diabetic rats
    Lulu Chen, Zixiang Chen, Zhuqiu Xu, Weifeng Feng, Xiaonan Yang, Zuoliang Qi · 2021 · Phytotherapy Research
  55. The ameliorative potential of Hyphaene thebaica on streptozotocin-induced diabetic nephropathy
    Mehrevan Abdelmoniem, Hesham N. Mustafa, Hoda A. Megahed, Mervat Agaibyi, Gehan A. Hegazy, Mahmoud Ahmed Touny El-Dabaa · 2015 · Folia Morphologica
  56. Homoeriodictyol protects human endothelial cells against oxidative insults through activation of Nrf2 and inhibition of mitochondrial dysfunction
    Tao Shen, Haizhen Li, Ailing Li, Yanru Li, Xiao‐Ning Wang, Dong‐Mei Ren · 2018 · Vascular Pharmacology
  57. Does curcumin or metformin attenuate oxidative stress and diabetic nephropathy in rats?
    Soheila Asadi, Mohammad Taghi Goodarzi, Jamshid Karimi, Mohammad Hashemnia, Iraj Khodadadi · 2018 · Journal of Nephropathology
  58. Curcumin: hopeful treatment of hemophilic arthropathy via inhibition of inflammation and angiogenesis
    Fatemeh Norooznezhad, Emerito Carlos Rodriguez-Merchan, Soheila Asadi, Amir Hossein Norooznezhad · 2019 · Expert Review of Hematology
  59. An Overview of the Posttranslational Modifications and Related Molecular Mechanisms in Diabetic Nephropathy
    Yu Cao, Zhao Yang, Ying Chen, Shuai Jiang, Zhen Biao Wu, Baoping Ding, Yang Yang, Zhenxiao Jin, Haifeng Tang · 2021 · Frontiers in Cell and Developmental Biology
  60. Steatosis is involved in the progression of kidney disease in a high-fat-diet-induced non-alcoholic steatohepatitis mouse model
    Shintaro Hamada, Tomoaki Takata, Kentaro Yamada, Marie Yamamoto, Yukari Mae, Takuji Iyama, Suguru Ikeda, Tsutomu Kanda, Takaaki Sugihara, Hajime Isomoto · 2022 · PLoS ONE
  61. Therapeutic Potential of Palmitoylethanolamide in Gastrointestinal Disorders
    Marija Branković, Tijana Gmizić, Marija Dukić, Marija D. Zdravkovic, Branislava Daskalovic, Davor Mrda, Novica Nikolić, Milica Brajković, Milan Gojgić, Jovana Lalatović et al. · 2024 · Antioxidants
  62. Molecular Therapeutics for Diabetic Kidney Disease: An Update
    Man Guo, Fang-Fang He, Chun Zhang · 2024 · International Journal of Molecular Sciences
  63. Synthetic oleanane triterpenoids: magic bullets or not?
    Hanna E. Abboud · 2013 · Kidney International
  64. Nrf2 Is Crucial to Graft Survival in a Rodent Model of Heart Transplantation
    Wei Wu, Quan Qiu, Huihui Wang, Samantha A. Whitman, Deyu Fang, Fangru Lian, Donna D. Zhang · 2013 · Oxidative Medicine and Cellular Longevity
  65. Heme oxygenase-1 contributes to the protective effect of resveratrol against endothelial dysfunction in STZ-induced diabetes in rats
    Asmaa S.A. Hammad, Al‐Shaimaa F. Ahmed, Gehan Hussein Heeba, Ashraf Taye · 2019 · Life Sciences
  66. Ampelopsin inhibits high glucose‐induced extracellular matrix accumulation and oxidative stress in mesangial cells through activating the Nrf2/HO‐1 pathway
    Chunping Dong, Guifu Wu, Hui Li, Yuan Qiao, Shan Gao · 2020 · Phytotherapy Research
  67. Effects of extremely low frequency pulsed magnetic fields on diabetic nephropathy in streptozotocin-treated rats
    Feijiang Li, Tao Lei, Kangning Xie, Xiaoming Wu, Chi Tang, Maogang Jiang, Juan Liu, Erping Luo, Guanghao Shen · 2016 · BioMedical Engineering OnLine
  68. Antioxidant mechanism of black garlic extract involving nuclear factor erythroid 2-like factor 2 pathway
    Ae Wha Ha, Woo Kyoung Kim · 2017 · Nutrition Research and Practice
  69. Role of STAT3 and NRF2 in Tumors: Potential Targets for Antitumor Therapy
    Yanjun Tian, Haiqing Liu, Meng-Wei Wang, Ruihao Wang, Guandong Yi, Meng Zhang, Ruijiao Chen · 2022 · Molecules
  70. Exenatide Increases IL-1RA Concentration and Induces Nrf-2‒Keap-1‒Regulated Antioxidant Enzymes: Relevance to β-Cell Function
    Paresh Dandona, Husam Ghanim, Sanaa Abuaysheh, Kelly Green, Sandeep Dhindsa, Antoine Makdissi, Manav Batra, Nitesh D Kuhadiya, Ajay Chaudhuri · 2018 · The Journal of Clinical Endocrinology & Metabolism
  71. Renal microRNA-144-3p is associated with transforming growth factor-β1-induced oxidative stress and fibrosis by suppressing the NRF2 pathway in hypertensive diabetic kidney disease
    Seung Ki Kim, Gwang Sun Bae, Taegeun Bae, Sae‐Kwang Ku, Bo-Hyun Choi, Mi‐Kyoung Kwak · 2024 · Free Radical Biology and Medicine
  72. Cinnamon: an aromatic condiment applicable to chronic kidney disease
    Laís de Souza Gouveia Moreira, Isabela de Souza da Costa Brum, Drielly Cristhiny Mendes de Vargas Reis, Liana Trugilho, Tuany Ramos Chermut, Marta Esgalhado, L. Cardozo, Peter Stenvinkel, Paul G. Shiels, Denise Mafra · 2023 · Kidney Research and Clinical Practice
  73. Decreased DANCR contributes to high glucose‐induced extracellular matrix accumulation in human renal mesangial cell via regulating the TGF ‐β/Smad signaling
    Feng Liu, Yiling Cao, Chun Zhang, Hua Su · 2023 · The FASEB Journal
  74. CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes
    Yan Yang, Jie Li, Lingqiang Zhang, Zeyuan Lin, Haiming Xiao, Xiaohong Sun, Meng Zhang, Peiqing Liu, Heqing Huang · 2020 · Pharmacological Research
  75. Charge-switchable, anti-oxidative molecule tuned polyelectrolyte multilayered films: Amplified polyelectrolyte diffusivity and accelerated diabetes wound healing
    Gang Zheng, Di Zhang, Qian Tang, Haiwei Ma, Xiaoyu Dong, Yanlin Chen, Wen-Fei Ni, Bailiang Wang, Huazi Xu, Liyan Shen · 2021 · Chemical Engineering Journal
  76. Supplementation of 17β-Estradiol Normalizes Rapid Gastric Emptying by Restoring Impaired Nrf2 and nNOS Function in Obesity-Induced Diabetic Ovariectomized Mice
    Jeremy C. Sprouse, Chethan Sampath, Pandu R. Gangula · 2020 · Antioxidants
  77. Dysregulation of Nrf2 Signaling in Diabetes: An Opportunity for a Multitarget Approach
    2015 · Journal of Diabetes & Metabolism
  78. Fabricating a mitochondrial viscosity-activated fluorescent probe for highly sensitive imaging of kidney injury in vivo
    Xiangui Zheng, Hongshuai Zhang, Yuan‐Yuan Wang, Mei Yuan, Xuefeng Yang, Liu Zeng, Longwei He, Dan Cheng · 2025 · Sensors and Actuators B Chemical
  79. Perturbation of Cellular Redox Status: Role of Nrf2, a Master Regulator of Cellular Redox
    Lokesh Gambhir, Garima Tyagi, Richa Bhardwaj, Neha Kapoor, Gaurav Sharma · 2022 · Biochemistry
  80. Nephroprotective Potential of Syringic Acid in Experimental Diabetic Nephropathy
    Bhoomika Sherkhane, Veera Ganesh Yerra, Anjana Sharma, Anil Kumar V, Chayanika Gundu, Arruri Vijay Kumar, Ashutosh Kumar · 2023 · Indian Journal of Pharmacology
  81. A preliminary evaluation of bardoxolone methyl for the treatment of diabetic nephropathy
    Merlin C. Thomas · 2012 · Expert Opinion on Drug Metabolism & Toxicology
  82. HX-1171 attenuates pancreatic β-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model
    Jimin Kim, Su‐Hyun Shin, Jong‐Koo Kang, Jae Wha Kim · 2018 · Oncotarget
  83. NQO1 Deficiency Aggravates Renal Injury by Dysregulating Vps34/ATG14L Complex during Autophagy Initiation in Diabetic Nephropathy
    Geum-Lan Hong, Kyung‐Hyun Kim, Chul‐Ho Lee, Tae‐Won Kim, Ju‐Young Jung · 2021 · Antioxidants
  84. SIK2 protects against renal tubular injury and the progression of diabetic kidney disease
    Bingyao Liu, Linlin Zhang, Hang Yang, Xinyu Chen, Hongting Zheng, Xiaoyu Liao · 2022 · Translational research
  85. Sea cucumber (Holothuria nobilis) hydrolysates improve diabetic nephropathy via suppression of oxidative stress in high-fat diet/streptozotocin-induced diabetic rats
    Tingting Wang, Lin Ping Zheng, Xiaoling Liu, Mouming Zhao · 2023 · Journal of Functional Foods
  86. Targeting the superoxide/nitric oxide ratio by L -arginine and SOD mimic in diabetic rat skin
    Aleksandra Janković, Carla Ferreri, Miloš R. Filipović, Ivana Ivanović‐Burmazović, Ana Stančić, Vesna Otašević, Aleksandra Korać, Biljana Buzadžić, Bato Korać · 2016 · Free Radical Research
  87. Curcumin/piperine modulates the butyrate levels and alleviates diabetic kidney disease via Nrf2/HO-1 signaling pathway
    Yinan Zhu, Lina Sun, Zhaoan Guo, Peiqing Xin, Feng Huang, Lei Song, Yulin Man, Miaomiao Ren, Zhongwei Ma, Ying Wang · 2025 · Renal Failure
  88. Metabolic rewiring and epigenetic reprogramming in leptin receptor-deficient db/db diabetic nephropathy mice
    Md Shahid Sarwar, David Cheng, Rebecca Mary Peter, Ahmad Shannar, Pochung Jordan Chou, Lujing Wang, Renyi Wu, Davit Sargsyan, Michael J. Goedken, Yujue Wang et al. · 2023 · European Journal of Pharmacology
  89. Retracted : Receptor for advanced glycation end products reveals a mechanism regulating thyroid hormone secretion through the SIRT1/Nrf2 pathway
    Xiao‐Jun Chen, Xiaohua Gong, Jin‐Ping Jie, Weihui Yu, Xiong Chen, Xuan Du, Qi Zhou, Wenjun Wu · 2018 · Journal of Cellular Biochemistry · Retracted
  90. Redox homeostasis and therapeutic modulation: the central role of oxidative stress and nuclear factor erythroid 2-related factor 2 (Nrf2) activation in systemic diseases and reproductive dysfunction
    Abhishek Kumar, Sivaraman Ramanarayanan · 2025 · Canadian Journal of Physiology and Pharmacology
  91. 17β-Estradiol Suppresses Gastric Inflammatory and Apoptotic Stress Responses and Restores nNOS-Mediated Gastric Emptying in Streptozotocin (STZ)-Induced Diabetic Female Mice
    Jeremy Sprouse, C. Sampath, P. Gangula · 2023 · Antioxidants
  92. Sulforaphane regulates AngII-induced podocyte oxidative stress injury through the Nrf2-Keap1/ho-1/ROS pathway
    Wen Lu · 2024 · Renal Failure
  93. Nuclear Factor Erythroid 2-Related Factor 2 Activator DDO-1039 Ameliorates Podocyte Injury in Diabetic Kidney Disease via Suppressing Oxidative Stress, Inflammation, and Ferroptosis
    Xing Liu, Xiuwen Zhai, Xiaoyu Wang, Xiaodong Zhu, Ziyue Wang, Zhengyu Jiang, Hao Bao, Zhao-hong Chen · 2024 · Antioxidants and Redox Signaling
  94. Role of oxidants and antioxidants in diabetic wound healing
    Manuela M. Martins‐Green, Shayan Saeed · 2020 · Elsevier eBooks
  95. Coronary Large Conductance Ca2+-Activated K+ Channel Dysfunction in Diabetes Mellitus
    Tong Lü, Hon-Chi Lee · 2021 · Frontiers in Physiology
  96. Extracts of Fruits and Vegetables Activate the Antioxidant Response Element in IMR-32 Cells
    Stephen Orena, Jennifer Owen, Fuxia Jin, Morgan Fabian, Nicholas D. Gillitt, Steven H. Zeisel · 2015 · Journal of Nutrition
  97. Eicosapentaenoic acid prevents salt sensitivity in diabetic rats and decreases oxidative stress
    Marianela Vara-Messler, Jorge Humberto Mukdsi, Natalia Osiecki, Evangelina Benizio, G Repossi, Ebenezer I. O. Ajayi, Nestor Horacio Garcia · 2019 · Nutrition
  98. Sulforaphane inhibits the production of Aβ partially through the activation of Nrf2-regulated oxidative stress
    Shunxi Zhang, Jiahe Zhao, Zhihuai Bai, Lina Luo, Fan Wu, Bao‐Long Li, Yujuan Shan · 2021 · Food & Function
  99. Diphenyl diselenide protects against diabetic kidney disease through modulating gut microbiota dysbiosis in streptozotocin-induced diabetic rats
    Xing Wang, Dongmei Long, Xingcan Peng, Jiaxuan Li, Maoting Zhou, Yu Wang, Xianghong Hu · 2024 · Frontiers in Pharmacology
  100. Nrf2 activator corosolic acid meliorates alloxan induced diabetic nephropathy in mice
    Priti S. Tidke, Chandragouda Raosaheb Patil · 2017 · Asian Pacific Journal of Tropical Biomedicine