LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance
Lan, Fei, Misu, Hirofumi, Chikamoto, Keita, Takayama, Hiroaki, Kikuchi, Akihiro, Mohri, Kensuke, Takata, Noboru, Hayashi, Hiroto +18 more·2014·Diabetes
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Items 101–158 of 158
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- Effect of a LECT2 on the immune response of peritoneal lecukocytes against Vibrio anguillarum in roughskin sculpinYingmei Chai, Bailin Cong, Shanshan Yu, Yingying Liu, Xin Man, Lujie Wang, Qian Zhu · 2018 · Fish & Shellfish Immunology
- Renal amyloidogenic leukocyte chemotactic factor 2 combined with IgA nephropathy: A case reportHongzhao Xu, Jia Ye, Xueyao Wang, Hui Wang, Jinyu Yu, Hao Wu · 2022 · Medicine
- Leukocyte cell-derived chemotaxin-2 and fibroblast growth factor 21 in alcohol-induced liver cirrhosisJarosław Jerzy Sak, Andrzej Prystupa, Paweł Kiciński, Dorota Luchowska-Kocot, Ewa Kurys-Denis, Hanna Bis-Wencel · 2021 · World Journal of Hepatology
- LECT2 modulates dendritic cell function after Helicobacter pylori infection via the CD209a receptorXiaofen Zhang, Kefang Sun, Chenxi Tang, Cen Li, Sha Li, Wei Zhu, Peihao Liu, Yishu Chen, Chaohui Yu, Lan Li · 2023 · Journal of Gastroenterology and Hepatology
- Hepatokines and Adipokines in Metabolic SyndromeAlpana Mukhuty, Samim Ali Mondal, Satinath Mukhopadhyay · 2023 · Annals of the National Academy of Medical Sciences (India)
- Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver diseaseDiego Paine‐Cabrera, Lisa K. Harvey, Dakota R. Robarts, Michele T. Pritchard, John P. Thyfault, Steven A. Weinman, Udayan M. Apte, Voytek Slowik · 2023 · Clinical and Translational Science
- Relationship between the changes in hepatokine levels and metabolic effects after laparoscopic sleeve gastrectomy in severely obese patientsAkira Umemura, Akira Sasaki, Toshinari Takamura, Hiroaki Takayama, Yumie Takeshita, Yosuke Toya, Keisuke Kakisaka, Yutaka Hasegawa, Yasushi Ishigaki · 2023 · Surgery Today
- Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in miceAkihiro Kikuchi, Hiroaki Takayama, Hirohiko Tsugane, Kazuhiro Shiba, Keita Chikamoto, Tatsuya Yamamoto, Seiichi Matsugo, Kiyo‐aki Ishii, Hirofumi Misu, Toshinari Takamura · 2020 · Scientific Reports
- Metabolic Dysfunction-Associated Steatotic Liver Disease and Sarcopenia: Review of LiteratureHiroki Nishikawa, Soo Ki Kim, Sachiyo Yoshio, AKIRA ASAI · 2026 · Journal of Clinical Medicine
- Hepatokine leukocyte cell‐derived chemotaxin 2 as a biomarker of insulin resistance, liver enzymes, and metabolic dysfunction‐associated steatotic liver disease in the general populationKeita Suzuki, Hiromasa Tsujiguchi, Akinori Hara, Yumie Takeshita, Hisanori Goto, Yujiro Nakano, Reina Yamamoto, Hiroaki Takayama, Atsushi Tajima, Tatsuya Yamashita et al. · 2024 · Journal of Diabetes Investigation
- Elevated serum levels of leukocyte cell-derived chemotaxin 2 are associated with the prevalence of metabolic syndromeXialei Zheng, Junmi Lu, Shaojun Xiang, Pu Zou, Hao Chen, Jing Liu, Cheng Chu Zeng, Yuhu He · 2024 · Acta Diabetologica
- LECT 2 Antagonizes FOXM1 Signaling via Inhibiting MET to Retard PDAC ProgressionXin Li, Pingping Lin, Ye Tao, Xin Jiang, Ting Li, Yunshan Wang, Chenjing Wang, Yu J Cao · 2021 · Frontiers in Cell and Developmental Biology
- Luseogliflozin and caloric intake restriction increase superoxide dismutase 2 expression, promote antioxidative effects, and attenuate aortic endothelial dysfunction in diet‐induced obese miceShigeru Kawade, Kazuma Ogiso, Sigfrid Casmir Shayo, Takahiko Obo, Aiko Arimura, Hiroshi Hashiguchi, Takahisa Deguchi, Yoshihiko Nishio · 2023 · Journal of Diabetes Investigation
- Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in ratsWeidong Li, Xia Jin-rong, Yan‐Shu Lian · 2019 · Molecular Medicine Reports
- Discovery of novel obesity genes through cross-ancestry analysisDeepro Banerjee, Santhosh Girirajan · 2024 · medRxiv
- Differentially expressed genes in cotyledon of ewes fed mycotoxinsJessica L. Britt, Rooksana E. Noorai, S. K. Duckett · 2020 · BMC Genomics
- Transcriptome analysis revealed the existence of family-specific regulation of growth traits in grass carpWeidong Ye, Mijuan Shi, Sijia Chen, You Duan, Yanxin Jiang, Yingyin Cheng, Wanting Zhang, Jiujiu Chen, Yaping Wang, Xiao-Qin Xia · 2023 · Genomics
- Global research trends and hotspots for leukocyte cell-derived chemotaxin-2 from the past to 2023: a combined bibliometric reviewWei Liu, Qin Wang, Jianishaya Yeerlan, Yirui Yan, Luke Xu, Cui Jia, Xinlian Liu, Lushun Zhang · 2024 · Frontiers in Immunology
- Green tea extracts reduce leukocyte cell–Derived chemotaxin 2 and selenoprotein P levels in the livers of C57BL/6J mice fed a high-fat dietShintaro Onishi, Hidefumi Kitazawa, Shinichi Meguro, Ichiro Tokimitsu · 2018 · Bioscience Biotechnology and Biochemistry
- Iron overload in steatotic hepatocytes drives systemic metabolic dysfunction via alterations in hepatokine productionHye Jin Jo, Ayoung Kim, Hyunsoo Rho, Ae Kyung Park, Gil-Hwan Kim, Seo Jeong Jo, Hao Yuxin, You-Jung Hong, Ji Min Yeon, Hwang Chan Yu et al. · 2026 · Journal of Clinical Investigation
- Relationship Between Adipose Tissue and Liver Dysfunction in Women with Polycystic Ovary Syndrome and Metabolic SyndromeSebastião Freitas de Medeiros, Gustavo Arantes Rosa Maciel · 2026 · Metabolites
- Effect of Intracerebroventricular Administration of Galanin-Like Peptide on Hepatokines in C57BL/6 J MiceSatoshi Hirako, Nobuhiro Wada, Yuzuru Iizuka, Takahiro Hirabayashi, Haruaki Kageyama, Hyounju Kim, Naoko Kaibara, Naoko Yanagisawa, Fumiko Takenoya, Seiji Shioda · 2024 · Journal of Molecular Neuroscience
- Plasma Leukocyte Cell-Derived Chemotaxin-2 as a Risk Factor of Sarcopenia: Korean Frailty and Aging Cohort StudyEun Roh, Soon Young Hwang, Miji Kim, Chang Won Won, Kyung Mook Choi · 2025 · Nutrients
- Protein misfolding, aggregation and other factors determining the amyloidogenic landscape of human leucocyte chemotaxin-2: A reviewAkhilesh Kumar, Sudarshan Singh Lakhawat, Naveen Kumar Malik, Vinay Sharma, Yashdeep Singh, Ananya Jain, Vinod Sharma, Sandeep Kumar Singh, Pushpender Kumar Sharma · 2025 · Archives of Biochemistry and Biophysics
- Associations of Leukocyte-Derived Chemotaxin-2 (LECT2) with Insulin Resistance and Metabolic Syndrome in Type 2 Diabetes: A Cross-Sectional StudyYujing Sha, Jiaping Lu, Rui Jin, Lian Li, Min Zhang · 2025 · Diabetes Metabolic Syndrome and Obesity
- Elevated LECT2 and PEDF in Pediatric MAFLD: Diagnostic Performance and Metabolic CorrelationsLanshu Yang, Hongbing Ni, Meiling Deng, Tuo Guo, Jie Zhang, Baolan Sun, Weixia Yang · 2025 · Diabetes Metabolic Syndrome and Obesity
- Lean metabolic dysfunction-associated steatotic liver disease: Current insights and knowledge gapsPraveen Sandeep Raj R., Rebecca John, Felix Manoharan, Asisha M. Janeela, Ashish Goel, Nitin Kapoor · 2026 · Best Practice & Research Clinical Endocrinology & Metabolism
- Circulating leukocyte cell-derived chemotaxin 2 and fibroblast growth factor 21 are negatively associated with cardiorespiratory fitness in healthy volunteersSundus Malaikah, Scott A. Willis, Joseph J. Henson, Jack Alistair Sargeant, Thomas E. Yates, Alice Emily Thackray, Fernanda Reistenbach Goltz, Matthew J Roberts, Danielle Bernard-Deshong, Guruprasad Padur Aithal et al. · 2023 · Applied Physiology, Nutrition, and Metabolism
- From Liver to Muscle: Crosstalk Mechanisms and Interventions in SarcopeniaQiquan Wang, Yao Meng, Xiang Wang, Xinqiang Lan, Guoxin Fan, Yang Xiang · 2025 · Health and Metabolism
- Micro RNAs as Biomarkers of Bariatric Surgery Outcome and Putative Regulators of Hepatokines Selectively after Gastric Bypass, but not Sleeve GastrectomyAida Zarfeshani · 2016 · Journal of Obesity and Bariatrics
- Will inhibition of cellular crosstalk resolve liver fibrosis?Edward N. Harris · 2022 · Hepatology
- Stéatose et résistance à l’insuline : implication des hépatokinesChantal Bertrand, Philippe Valet, Isabelle Castan‐Laurell · 2015 · Obésité
- Ectopic Fat Accumulation in the Liver and Glucose HomeostasisToshinari Takamura, Hirofumi Misu, Shuichi Kaneko · 2016 · Springer eBooks
- III. Relation with Type II Diabetes: Regulation by HepatokinesHirofumi Misu · 2016 · Nihon Naika Gakkai Zasshi
- Adipose tissue metabolism and cardiometabolic health in obesityStinkens · 2017
- Early Hepatic Signals of Fat OverloadJavier Thomas Gonzalez · 2020 · Journal of Nutrition
- Rôle des hépatokines dans le dialogue inter-organes en physiologie et physiopathologieAude Pacheco, Catherine Postic · 2020 · Médecine des Maladies Métaboliques
- Hepatokine ERAP1 impairs skeletal muscle insulin sensitivity via ADRB2/PKA pathwayFeifan Guo, Yuguo Niu, Haizhou Jiang, Hanrui Yin, Fenfen Wang, Xiaoming Hu, Shanghai Chen · 2020 · Research Square
- An amyloidosis-associated polymorphism does not alter LECT2 stability in vitroLiudmila Belonogov, Paris E. Taylor, Sherry Wong, Gareth J. Morgan · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Markers of Liver Function and Insulin ResistanceVicente Aleixandre Benites-Zapata, Sofía Lorena Bohórquez-Medina, Andrea Lisbet Bohórquez-Medina · 2022 · Biomarkers in disease
- HepatokineH. Fiedler · 2019 · Springer Reference Medizin
- HepatokineH. Fiedler · 2018 · Springer eBooks
- Markers of Liver Function and Insulin ResistanceVicente Aleixandre Benites-Zapata, Sofía Lorena Bohórquez-Medina, Andrea Lisbet Bohórquez-Medina · 2022 · Biomarkers in disease
- Transcriptome analysis revealed the existence of family-specific regulation of growth traits in grass carpWeidong Ye, Mijuan Shi, Sijia Chen, You Duan, Yanxin Jiang, Yingyin Cheng, Wanting Zhang, Yaping Wang, Xiao-Qin Xia · 2023 · Research Square
- Renal Amyloidogenic Leukocyte Chemotactic Factor 2 Combined with Immunoglobulin A Nephropathy: 2 Case Reports and literature reviewLi Dan Zhao, Yanan Li, Ruihua Shen, Dan Niu, Wei xia Han, Chen Wang, Shulei Yao, Xiao hua Zhang, Lingyun Zhang, Lihua Wang et al. · 2024 · Research Square
- The Hepatokine Leukocyte Cell-Derived Chemotaxin-2 Is Elevated in People with Impaired Glycaemic Regulation and Augmented by Acute ExerciseBuket Engin, Scott A. Willis, Sundus Malaikah, Jack Alistair Sargeant, David J. Stensel, Charlotte Jelleyman, Gaël Ennequin, Guruprasad Padur Aithal, Thomas E. Yates, James A. King · 2024 · Livers
- General Internal Medicine VICündullah Torun, Osman Cüre, Kuddusi Cengiz, Kadir İlkkılıç, Ekrem Algün, Mustafa Metın Donma, Sibel Çiğdem Tuncer, Nilgün Altan, Aylin Sepici Dinçel, Funda Kosava et al. · 2024 · Akademisyen Kitabevi eBooks
- Muscle-Liver Crosstalk and SarcopeniaDavid Pérez-Torres, Isabel Canas-Pérez · 2025 · Springer eBooks
- Additional file 1 of Buddleoside-rich Chrysanthemum indicum L. extract modulates macrophage-mediated inflammation to prevent metabolic syndrome induced by unhealthy dietYiqing Zhou, Su, Jie, Dong, Yingjie, He, Ziwen, Wang, Yajun, Chen, Suhong, Guiyuan Lv · 2024 · Figshare
- Homéostasie des céramides et hépatopathies métaboliquesMarion Régnier · 2018 · theses.fr (ABES)
- Rôle de LECT2 dans les maladies stéatosiques non alcooliques du foieSandrine Pham · 2020 · theses.fr (ABES)
- Mise au point d’un nouvel outil diagnostique de l’obésité sarcopénique : relations avec la dysfonction du tissu adipeux, l’insulinorésistance et la sévérité de l’atteinte hépatiqueVittoria Zambon Azevedo · 2024 · theses.fr (ABES)
- LS21013A-06, a PDE4 inhibitor, preserves blood-brain barrier integrity in experimental ischemic stroke models through PKA-dependent modulation of LECT2Jiakang Wang, Chunyuan Zeng, Fei Ye, H Wang, Jiangping Xu · 2026 · European Journal of Pharmacology
- Cryo-EM structures of ALECT2 filaments from human renal biopsiesJian-Lin Zheng, Yu-Xin Zheng, Kai Chen, S X Wang, Jiawei Liang, S X Wang, Li Yang, Yang Shi · 2026 · Nature Communications
- Hepatic Senp2 deletion resolves the angiogenic switch in fibrosis via β-catenin/LECT2.X. Dou, Ying-Fei Peng, F. Chen, Te Liu, Bai-Shen Pan, Bei-Li Wang, Wei Guo, Dong-An Zhu, Ying Zhao, D. Chang · 2026 · Biochemical and Biophysical Research Communications - BBRC
- Key Hepatokines Linking MASLD and Type 2 Diabetes: From Pathophysiological Mechanisms to Therapeutic ModulationLiliana Georgeta Foia, Ancuța Goriuc, Ionut Alexandru Luchian, Dana Gabriela Budală, Vasilica Toma, Mária Bogdán, Bogdan Minea, Larisa Ghemiș · 2026 · International Journal of Molecular Sciences