Inhibiting microglia expansion prevents diet-induced hypothalamic and peripheral inflammation
André, Caroline, Guzman-Quevedo, Omar, Rey, Charlotte, Rémus-Borel, Julie, Clark, Samantha, Castellanos-Jankiewicz, Ashley, Ladeveze, Elodie, Leste-Lasserre, Thierry +4 more·2017·Diabetes
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- Addition of Opuntia ficus-indica Reduces Hypothalamic Microglial Activation and Improves Metabolic Alterations in Obese Mice Exposed to a High-fat DietMercedes Victoria Urquiza-Martínez, Héctor Eduardo Martínez‐Flores, Omar Guzmán‐Quevedo, Ana Elisa Toscano, Raul Manhães‐de‐Castro, Luz Torner, Rosalío Mercado-Camargo, Rosa Elena Pérez-Sánchez, María Carmen Bartolomé‐Camacho · 2020 · Journal of Food and Nutrition Research
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- Dual functions of CNS inflammation in food intake and metabolic regulationTien-Jui Lee, Sara L. Hargrave, Kimberly P. Kinzig · 2020 · Brain Research
- Brain Inflammation and Endoplasmic Reticulum StressI. Çakır, E. Nillni · 2018 · Springer eBooks
- Effects of Intranasally Administered Insulin and Gangliosides on Metabolic Parameters and Activity of the Hepatic Insulin System in Rats with Type 2 Diabetes MellitusIrina O. Zakharova, Liubov V. Bayunova, Kira Viktorovna Derkach, I. O. Ilyasov, Alexander Olegovich Shpakov, Natalia F. Avrova · 2022 · Journal of Evolutionary Biochemistry and Physiology
- Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesityJiahui Liu, Ali Hussainy Zaidi, Christian J. Pike · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Oral cytarabine ocfosfate pharmacokinetics and assessment of leukocyte biomarkers in normal dogsDanielle M. Zwueste, Karen M. Vernau, William Vernau, Bruno H. Pypendop, Heather K. DiMaio Knych, Carlos Alberto Rodrigues, Amir Kol, María Questa, Peter J. Dickinson · 2023 · Journal of Veterinary Internal Medicine
- Intermittent Overconsumption of High Fat Diet Promotes Microglial Reactivity in the Hypothalamus and Hindbrain of Female RatsAlexis A. Campanile, Lisa A. Eckel · 2025 · Cells
- Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retinaYixin Wang, Mahmoud Halawa, Anupriya Chatterjee, Rachana Eshwaran, Yi Hua Qiu, Yohanes Cakrapradipta Wibowo, Jianyuan Pan, Thomas Wieland, Yuxi Feng · 2023 · Molecular Medicine
- A high-fat diet influences neural stem and progenitor cell environment in the medulla of adult miceEriko Furube, Masahiro Ohgidani, Yusuke Tanaka, Seiji Miyata, Shigetaka Yoshida · 2024 · Neuroscience
- Fat food exacerbates post-prandial hypothalamic inflammation involving GFAP+ cells and microgliaCéline Cansell, Katharina Stobbe, Ophélia Le Thuc, CA. Mosser, Selma Ben Fradj, Joris Leredde, Cynthia Lebeaupin, Delphine Debayle, Lucile Fleuriot, Frédéric Brau et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- A Cross-sectional Data Analysis between Serum Total Bilirubin and Potential Obesity Indices in US AdultsLibing Tian, Jian Gang Zhang, Yanshen Chen, Yong Feng, Qing Liu, Cunbao Ling · 2025 · Current Molecular Medicine
- Impact of the flavonoid-induced intestinal microbiota modulation on global energy metabolism: implication for obesityOmar Guzmán‐Quevedo, Alana Natalícia Vasconcelos de Araújo, Pedro A. Romero-Juárez, Jordania Candice Costa Silva, Gonzalo Soria-Melgarejo, Luz Torner, Jailane de Souza Aquino · 2026 · Frontiers in Nutrition
- NPV-BSK805, an Antineoplastic Jak2 Inhibitor Effective in Myeloproliferative Disorders, Causes Adiposity in Mice by Interfering With the Action of LeptinMagalie Haissaguerre, Amandine Ferrière, Samantha Clark, Omar Guzmán‐Quevedo, Antoine Tabarin, Daniela Cota · 2018 · Frontiers in Pharmacology
- Microglial Proliferation in Obesity: When, Where, Why, and What Does It Mean?Julie Ann Chowen, Tamás L. Horváth, Jesús Argente · 2017 · Diabetes
- Novel Hypothalamic Mechanisms in the Pathophysiological Control of Body Weight and MetabolismDiego Pérez–Tilve · 2017 · Endocrinology
- Senotherapeutic approach to age-related endocrine diseasesŞeydanur Turgut, Gülnur Andican · 2025 · Advances in pharmacology
- Dependence of fasting-induced hypothalamic anti-inflammatory microglia mechanisms on adrenal glucocorticoid secretionBalázs Juhász, Krisztina Horváth, Dániel Kuti, Szilamér Ferenczi, Zsuzsanna Winkler, Krisztina Kovács · 2025 · Brain Behavior and Immunity
- Analysis of the Aerial Parts of Millettia speciosa Champ. and Mechanistic Study of Its Active Ingredient Formononetin in Improving Metabolic SyndromeWenjing Niu, Ruhai Jian, Lishen Zeng, Ziyue Huang, Cai Jinyan · 2025 · Food Science & Nutrition
- Acute changes in systemic glycaemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasisWineke Bakker, Casper Gravesen Salinas, Mónica Imbernón, Daniela Herrera Moro Chao, Rim Hassouna, Chloe Morel, Claire Martin, Giuseppe Gangarossa, R Denis, Julien Castel et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Efeitos da programação nutricional neonatal em células da glia hipotalâmica em ratos juvenis e adultosLucas Kniess Debarba · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Microglial adipobiology: a new concept for understanding the adipose tissue-brain crosstalk in health and diseaseMarin Zhelezov · 2019 · Adipobiology
- Investigating Antipsychotic Drug-induced Impairment of Central Energy HomeostasisChantel Kowalchuk · 2019 · TSpace (University of Toronto)
- The Dopamine D2R Antagonist Trifluoperazine Suppresses High-Fat Diet-Induced Hyperglycemia and Hypothalamic Gliosis in Obese MiceHui-Ting Huang, Pei‐Chun Chen, Po See Chen, Wen‐Tai Chiu, Yu‐Min Kuo, Shun‐Fen Tzeng · 2021 · Research Square
- Faculty Opinions recommendation of Microglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility.Shin‐ichiro Imai · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Receptores LXR e seu papel na modulação do metabolismo e função de macrófagos residentes do tecido adiposo: uma nova ferramenta para o tratamento de doenças metabólicasJéssica Aparecida da Silva Pereira · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- A little less heavy, or a little less hated? Exploring the consequences of a neuroinflammation model of obesityJoshua Reilly · 2023 · Queensland University of Technology
- Avaliação do papel do TGF-ß1 e da microglia na resposta inflamatória hipotalâmica induzida por ácidos graxos saturadosNatália Ferreira Mendes · 2021
- Microgliosis driven by palmitate exposure alters energy metabolism and extracellular vesicles release that impact behavior and systemic metabolismGabriela Cristina de Paula, Blanca I. Aldana, Roberta Battistella, Rosalía Fernández‐Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
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- Computational detection, characterization, and clustering of microglial cells in a mouse model of fat-induced postprandial hypothalamic inflammationClara Sanchez, Morgane Nadal, Céline Cansell, Sarah Laroui, Xavier Descombes, Carole Rovère, Éric Debreuve · 2025 · Methods
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- Additional file 1 of Extracellular vesicles released from microglia after palmitate exposure impact brain functionGabriela Cristina de Paula, Blanca Aldana, Roberta Battistella, Rosalía Fernández‐Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte · 2024 · Figshare
- Additional file 5 of Extracellular vesicles released from microglia after palmitate exposure impact brain functionGabriela Cristina de Paula, Blanca Aldana, Roberta Battistella, Rosalía Fernández‐Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte · 2024 · Figshare
- Additional file 1 of C1q/TNF-related protein 4 restores leptin sensitivity by downregulating NF-κB signaling and microglial activationYe, Liu, Jia, Gongwei, Li, Yuejie, Ying Wang, Chen, Hong, Lehua Yu, Wu, Dandong · 2021 · Figshare
- Additional file 3 of Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesityXiao, Xiaoxia, Huiling Hu, Zhong, Yadi, Yingjian Chen, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Qi Wang, Gao, Yong · 2024 · Figshare
- Additional file 2 of Extracellular vesicles released from microglia after palmitate exposure impact brain functionGabriela Cristina de Paula, Blanca Aldana, Roberta Battistella, Rosalía Fernández‐Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte · 2024 · Figshare
- Additional file 4 of Extracellular vesicles released from microglia after palmitate exposure impact brain functionGabriela Cristina de Paula, Blanca Aldana, Roberta Battistella, Rosalía Fernández‐Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte · 2024 · Figshare
- Additional file 6 of Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesityXiao, Xiaoxia, Huiling Hu, Zhong, Yadi, Yingjian Chen, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Qi Wang, Gao, Yong · 2024 · Figshare
- Additional file 5 of Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesityXiao, Xiaoxia, Huiling Hu, Zhong, Yadi, Yingjian Chen, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Qi Wang, Gao, Yong · 2024 · Figshare
- Additional file 3 of Extracellular vesicles released from microglia after palmitate exposure impact brain functionGabriela Cristina de Paula, Blanca Aldana, Roberta Battistella, Rosalía Fernández‐Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte · 2024 · Figshare
- Additional file 1 of Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retinaWang, Yixin, Mahmoud Halawa, Anupriya Chatterjee, Rachana Eshwaran, Yi Hua Qiu, Yohanes Cakrapradipta Wibowo, Pan, Jianyuan, Wieland, Thomas, Yuxi Feng · 2024 · Figshare
- Additional file 4 of Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesityXiao, Xiaoxia, Huiling Hu, Zhong, Yadi, Yingjian Chen, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Qi Wang, Gao, Yong · 2024 · Figshare
- Additional file 2 of Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesityXiao, Xiaoxia, Huiling Hu, Zhong, Yadi, Yingjian Chen, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Qi Wang, Gao, Yong · 2024 · Figshare
- Additional file 1 of Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesityXiao, Xiaoxia, Huiling Hu, Yadi Zhong, Yingjian Chen, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Qi Wang, Gao, Yong · 2024 · Figshare
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