Effects of the Dipeptidyl Peptidase-IV Inhibitor Vildagliptin on Incretin Hormones, Islet Function, and Postprandial Glycemia in Subjects With Impaired Glucose Tolerance

Rosenstock, Julio; Foley, James E.; Rendell, Marc; Landin-Olsson, Mona; Holst, Jens J.; Deacon, Carolyn F.; Rochotte, Erika; Baron, Michelle A.

doi:10.2337/dc07-1616

Effects of the Dipeptidyl Peptidase-IV Inhibitor Vildagliptin on Incretin Hormones, Islet Function, and Postprandial Glycemia in Subjects With Impaired Glucose Tolerance

Objective This study was conducted to determine the effects of vildagliptin on incretin hormone levels, islet function, and postprandial glucose control in subjects with impaired glucose tolerance (IGT). Research design and methods A 12-week, double-blind, randomized, parallel-group study compari…