Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

Dasu, Mohan R., Devaraj, Sridevi, Park, Samuel, Jialal, Ishwarlal·2010·Diabetes Care

Cited by (571)

Items 101–200 of 571

  1. TNF-α mediates increased susceptibility to ischemic AKI in diabetes
    Guofeng Gao, Binzhi Zhang, Ganesan Ramesh, Daniel Betterly, Raghu Kempegowda Tadagavadi, Weiwei Wang, William Brian Reeves · 2013 · American Journal of Physiology-Renal Physiology
  2. Toll-like receptors 2 and 4 mediate hyperglycemia induced macrovascular aortic endothelial cell inflammation and perturbation of the endothelial glycocalyx
    Roma Pahwa, Palanisamy Nallasamy, Ishwarlal Jialal · 2016 · Journal of Diabetes and its Complications
  3. Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy
    Xin Guo, Mei Xue, Chunjun Li, Wei Yang, Shanshan Wang, Ze-jun Ma, Xiaona Zhang, Xiaoyu Wang, Ran Zhao, Baocheng Chang et al. · 2016 · Journal of Ethnopharmacology
  4. Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance
    Tina Märker, Henrike Sell, Pia Zilleßen, Anja Glöde, Jennifer Kriebel, D. Margriet Ouwens, Piet Pattyn, Johannes B Ruige, Susanne Famulla, Michael Roden et al. · 2012 · Diabetes
  5. Association of Toll-Like Receptor 4 Polymorphisms with Diabetic Foot Ulcers and Application of Artificial Neural Network in DFU Risk Assessment in Type 2 Diabetes Patients
    Kanhaiya Singh, Vivek Kumar Singh, Neeraj Kumar Agrawal, Sanjeev Gupta, Kiran Singh · 2013 · BioMed Research International
  6. Albumin stimulates renal tubular inflammation through a HSP70-TLR4 axis in early diabetic nephropathy
    Huei‐Fen Jheng, Pei-Jane Tsai, Yi-Lun Chuang, Yi-Ting Sheng, Ting-An Tai, Wen-Chung Chen, Chuan-Kai Chou, Li‐Chun Ho, Ming‐Jer Tang, Kuei-Tai A. Lai et al. · 2015 · Disease Models & Mechanisms
  7. Monocytes and macrophages as protagonists in vascular complications of diabetes
    Kanter, Jenny E., Hsu, Cheng-Chieh, Bornfeldt, Karin E. · 2020 · Frontiers in Cardiovascular Medicine
  8. An Integrated Approach to Skeletal Muscle Health in Aging
    Deborah Agostini, Marco Gervasi, Fabio Ferrini, Alessia Bartolacci, Alessandro Stranieri, Giovanni Piccoli, Elena Barbieri, Piero Sestili, Antonino Patti, Vilberto Stocchi et al. · 2023 · Nutrients
  9. Plasma HMGB-1 Levels in Subjects with Obesity and Type 2 Diabetes: A Cross-Sectional Study in China
    Hang Wang, Hua Qu, Huacong Deng · 2015 · PLoS ONE
  10. Neutrophil and Monocyte Bactericidal Responses to 10 Weeks of Low‐Volume High‐Intensity Interval or Moderate‐Intensity Continuous Training in Sedentary Adults
    David B. Bartlett, Sam O. Shepherd, Oliver J. Wilson, Ahmed Adlan, Anton J. M. Wagenmakers, Christopher S. Shaw, Janet M. Lord · 2017 · Oxidative Medicine and Cellular Longevity
  11. Microbiota Transplant in the Treatment of Obesity and Diabetes: Current and Future Perspectives
    Michael Napolitano, Mihai Covașă · 2020 · Frontiers in Microbiology
  12. Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
    Carolina Soares Moura, Pablo Christiano Barboza Lollo, Priscila Neder Morato, Jaime Amaya‐Farfán · 2018 · Nutrients
  13. Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation
    Nadeem Akhter, Ashraf Said Al Madhoun, Hossein Arefanian, Ajit Wilson, Shihab Kochumon, Reeby Thomas, Steve Shenouda, Fahd Al‐Mulla, Rasheed Ahmad, Sardar T. A. K. Sindhu · 2019 · Cellular Physiology and Biochemistry
  14. Expatiating the molecular approaches of HMGB1 in diabetes mellitus: Highlighting signalling pathways via RAGE and TLRs
    Tapan Behl, Eshita Sharma, Aayush Sehgal, Ishnoor Kaur, Arun Kumar, Rashmi Arora, Giridhari Pal, Munish Kakkar, Ravinder Kumar Kaundal, SIMONA GABRIELA BUNGAU · 2021 · Molecular Biology Reports
  15. Toll‐like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes
    Clara Y. Westwell-Roper, Dominika Nąckiewicz, Meixia Dan, Jan A. Ehses · 2014 · Immunology and Cell Biology
  16. Polyunsaturated fatty acids and type 2 diabetes: Impact on the glycemic control mechanism
    Olívia Gonçalves Leão Coelho, Bárbara Pereira da Silva, Daniela Mayumi Usuda Prado Rocha, Lílian Lelis Lopes, Rita de Cássia Gonçalves Alfenas · 2016 · Critical Reviews in Food Science and Nutrition
  17. Role of Toll-like receptors in diabetic nephropathy
    Harshini Mudaliar, Carol A. Pollock, Usha Panchapakesan · 2014 · Clinical Science
  18. Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?
    Joshua Juwono, Ryan D. Martinus · 2016 · Journal of Diabetes Research
  19. The Complex Interplay between Lipids, Immune System and Interleukins in Cardio-Metabolic Diseases
    Stella Bernardi, Annalisa Marcuzzi, Elisa Piscianz, Alberto Tommasini, Bruno Fabris · 2018 · International Journal of Molecular Sciences
  20. Lactobacillus paracasei modulates the gut microbiota and improves inflammation in type 2 diabetic rats
    Zhu Zeng, Xiaoxuan Guo, Jinlan Zhang, Qipeng Yuan, Shangwu Chen · 2021 · Food & Function
  21. The role of inflammation in diabetic kidney disease
    Su Woong Jung, Ju-Young Moon · 2021 · The Korean Journal of Internal Medicine
  22. Acute high-intensity interval exercise reduces human monocyte Toll-like receptor 2 expression in type 2 diabetes
    Cody Garett Durrer, Monique E. François, Helena Neudorf, Jonathan P. Little · 2017 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  23. Understanding and Modulating the Toll Like Receptors (TLRs) and NOD Like Receptors (NLRs) Cross Talk in Type 2 Diabetes
    Bhumika Prajapati, Prasant Kumar Jena, Parth Rajput, Kaveri Purandhar, Sriram Seshadri · 2014 · Current Diabetes Reviews
  24. Association between maternal diabetes and neurodevelopmental outcomes in children: a systematic review and meta-analysis of 202 observational studies comprising 56·1 million pregnancies
    Wenrui Ye, Cong Luo, Jun Zhou, Xisong Liang, Jie Wen, Jing Huang, Yu Zeng, Yinghua Wu, Yong Gao, Zhixiong Liu et al. · 2025 · The Lancet Diabetes & Endocrinology
  25. The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes
    Maurício da Silva Krause, Patrícia Martins Bock, H Takahashi, Paulo Ivo Homem de Bittencourt, Philip Newsholme · 2015 · Clinical Science
  26. Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease
    Fernanda S. Manoel-Caetano, Danilo J. Xavier, Adriane Feijó Evangelista, Paula Takahashi, Cristhianna V. A. Collares, Denis Puthier, Maria Cristina Foss‐Freitas, Milton César Foss, Eduardo Antônio Donadi, Geraldo Aleixo Silva Passos et al. · 2012 · Gene
  27. Increased Toll-Like Receptors Activity and TLR Ligands in Patients with Autoimmune Thyroid Diseases
    Shiqiao Peng, Chenyan Li, Xinyi Wang, Xin Liu, Cheng Han, Ting Jin, Shanshan Liu, Xiaowen Zhang, Hanyi Zhang, Xue He et al. · 2016 · Frontiers in Immunology
  28. Increased Expression of the Innate Immune Receptor TLR10 in Obesity and Type-2 Diabetes: Association with ROS-Mediated Oxidative Stress
    Sardar T. A. K. Sindhu, Nadeem Akhter, Shihab Kochumon, Reeby Thomas, Ajit Wilson, Steve Shenouda, Jaakko O. Tuomilehto, Rasheed Ahmad · 2018 · Cellular Physiology and Biochemistry
  29. Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury
    Miaomiao Wei, Zhigui Li, Lu Xiao, Zhuo Ru Yang · 2015 · Molecular Immunology
  30. High Mobility Group Box-1 (HMGB1): A Potential Target in Therapeutics
    Eyaldeva C. Vijayakumar, Lokesh Kumar Bhatt, Kedar S. Prabhavalkar · 2019 · Current Drug Targets
  31. Toll-like receptor 2/4 links to free fatty acid-induced inflammation and β-cell dysfunction
    Jiajing Yin, Yongde Peng, Jingcheng Wu, Yufan Wang, Lili Yao · 2013 · Journal of Leukocyte Biology
  32. Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosus
    Samuel K. Shimp, Cristen B. Chafin, Nicole L. Regna, Sarah E. Hammond, Molly A. Read, David L. Caudell, M. Nichole Rylander, Christopher M. Reilly · 2012 · Cellular and Molecular Immunology
  33. Resveratrol supplementation decreases blood glucose without changing the circulating CD14 + CD16 + monocytes and inflammatory cytokines in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study
    Hadi Khodabandehloo, ShadiSadat Seyyedebrahimi, Ensieh Nasli‐Esfahani, Farideh Razi, Reza Meshkani · 2018 · Nutrition Research
  34. Hyperglycemia induces inflammatory mediators in the human chorionic villous
    Simone Correa‐Silva, Aline Paixão Alencar, Jusciéle Brogin Moreli, Alexandre Urban Borbely, Larissa de Sá Lima, Cristóforo Scavone, Débora Cristina Damasceno, Marilza Vieira Cunha Rudge, Estela Maris Andrade Forell Bevilacqua, Iracema de Mattos Paranhos Calderon · 2018 · Cytokine
  35. Disulfiram blocks inflammatory TLR4 signaling by targeting MD-2
    Yang Bai, Rui Min, Pengcheng Chen, Shenglin Mei, Fan Deng, Zengzhang Zheng, Cong Jiang, Rui Miao, Zeyu Wu, Peng Zhang et al. · 2023 · Proceedings of the National Academy of Sciences
  36. Toll-like receptor 4 and tumor necrosis factor-alpha as diagnostic biomarkers for diabetic peripheral neuropathy
    Tao Zhu, Qingsheng Meng, Jian Ji, Xiaoli Lou, Lijuan Zhang · 2014 · Neuroscience Letters
  37. Increased Expression of Toll-Like Receptor 2 in Rat Diabetic Nephropathy
    Fanglin Li, Niansheng Yang, Lili Zhang, Hechang Tan, Bin Huang, Yingjie Liang, Miaoyan Chen, Xueqing Yu · 2010 · American Journal of Nephrology
  38. Effect of simvastatin or its combination with ezetimibe on Toll-like receptor expression and lipopolysaccharide – Induced cytokine production in monocytes of hypercholesterolemic patients
    Elisavet Moutzouri, Constantinos C. Tellis, Kleopatra Rousouli, Evangelos N. Liberopoulos, Haralambos J. Milionis, Moses Elisaf, Alexandros D. Tselepis · 2012 · Atherosclerosis
  39. HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA
    Xiangyu Guo, Yu Shi, Ping Du, Jiahui Wang, Yelei Han, Bei Sun, Jing Feng · 2019 · Life Sciences
  40. Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway
    Simin Tian, Min Wang, Chenyue Liu, Hongbin Zhao, Baosheng Zhao · 2019 · BMC Complementary and Alternative Medicine
  41. Effects of Diabetes Mellitus-Related Dysglycemia on the Functions of Blood–Brain Barrier and the Risk of Dementia
    Mateusz Wątroba, Anna D. Grabowska, Dariusz Szukiewicz · 2023 · International Journal of Molecular Sciences
  42. Update on the Pathogenesis, Diagnosis, and Treatment of Diabetic Tubulopathy
    Danfeng Liu, Xiaojie Chen, Weiting He, Min Lu, Qiuling Li, Shaogui Zhang, Jianteng Xie, Yifan Zhang, Weimin Wang · 2024 · Integrative Medicine in Nephrology and Andrology
  43. Differential regulation of TLR4 expression in human B cells and monocytes
    Lisa M Ganley-Leal, Y Liang, Madhumita Jagannathan‐Bogdan, Francis A. Farraye, Barbara S. Nikolajczyk · 2010 · Molecular Immunology
  44. MicroRNA-146a-5p Mediates High Glucose-Induced Endothelial Inflammation via Targeting Interleukin-1 Receptor-Associated Kinase 1 Expression
    Wan‐Yu Lo, Ching‐Tien Peng, Huang-Joe Wang · 2017 · Frontiers in Physiology
  45. Skeletal muscle ceramides and relationship with insulin sensitivity after 2 weeks of simulated sedentary behaviour and recovery in healthy older adults
    Paul T. Reidy, Alec I. McKenzie, Ziad S. Mahmassani, Vincent R. Morrow, Nikol M. Yonemura, Paul Nathan Hopkins, Robin L. Marcus, Matthew Thomas Rondina, Yu Kuei Lin, Micah John Drummond · 2018 · The Journal of Physiology
  46. IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wounds
    Ruchi Roy, Janet P. Zayas, Mohamed F. Mohamed, Anahita Aboonabi, Kaylee Delgado, Jennillee Wallace, Mohammad Bayat, Timothy Michael Kuzel, Jochen Reiser, Sasha H. Shafikhani · 2021 · Journal of Investigative Dermatology
  47. The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling
    Kohei Uchimura, Manabu Hayata, Teruhiko Mizumoto, Yoshikazu Miyasato, Yutaka Kakizoe, Jun Morinaga, Tomoaki Onoue, Rika Yamazoe, Miki U. Ueda, Masataka Adachi et al. · 2014 · Nature Communications
  48. Regulation of the clock gene expression in human adipose tissue by weight loss
    Olga Pivovarova‐Ramich, Özlem Gögebakan, Stephanie Sucher, J Groth, Veronica Murahovschi, Katharina Kessler, MA Osterhoff, Natalia N. Rudovich, Achim Kramer, Andreas F. H. Pfeiffer · 2016 · International Journal of Obesity
  49. The function and mechanism of HMGB1 in lung cancer and its potential therapeutic implications (Review)
    Lei Wu, Lili Yang · 2018 · Oncology Letters
  50. Effects of combined aerobic and resistance training on the glycolipid metabolism and inflammation levels in type 2 diabetes mellitus
    Yuan Liu, Suixin Liu, Ying Cai, Kangling Xie, Wenliang Zhang, Zheng Fan · 2015 · Journal of Physical Therapy Science
  51. Role of Toll‐like Receptors 2 and 4 in Mediating Endothelial Dysfunction and Arterial Remodeling in Primary Arterial Antiphospholipid Syndrome
    Y. Benhamou, Jérémy Bellien, G. Armengol, Ebba Bråkenhielm, Sahil Adriouch, Michèle Iacob, Isabelle Rémy‐Jouet, Véronique Le Cam‐Duchez, Christelle Monteil, Sylvanie Renet et al. · 2014 · Arthritis & Rheumatology
  52. Role of HMGB1 signaling in the inflammatory process in diabetic retinopathy
    Jena J. Steinle · 2020 · Cellular Signalling
  53. Resveratrol ameliorates experimental periodontitis in diabetic mice through negative regulation of TLR4 signaling
    Lei Zhen, Desheng Fan, Yan Zhang, Xinming Cao, Liming Wang · 2014 · Acta Pharmacologica Sinica
  54. Gα12/13 signaling in metabolic diseases
    Yoon Mee Yang, Da‐Sol Kuen, Yeonseok Chung, Hitoshi Kurose, Sang Geon Kim · 2020 · Experimental & Molecular Medicine
  55. High-Fat Diet Induces Toll-Like Receptor 4-Dependent Macrophage/Microglial Cell Activation and Retinal Impairment
    Jong‐Jer Lee, Pei‐Wen Wang, I-Hui Yang, Hsiu‐Mei Huang, Chia‐Shiang Chang, Chia‐Lin Wu, Jiin‐Haur Chuang · 2015 · Investigative Ophthalmology & Visual Science
  56. Minireview: Emerging Concepts in Islet Macrophage Biology in Type 2 Diabetes
    David Lee Morris · 2015 · Molecular Endocrinology
  57. Toll like receptors and pancreatic diseases: From a pathogenetic mechanism to a therapeutic target
    Matteo Santoni, Kalliopi Andrikou, Valeria Sotte, Alessandro Bittoni, Andrea Lanese, Chiara Pellei, Francesco Piva, Alessandro Conti, Massimo Nabissi, Giorgio Santoni et al. · 2015 · Cancer Treatment Reviews
  58. Recent advances in managing and understanding diabetic nephropathy
    Sydney C.W. Tang, Gary C.W. Chan, Kar Neng Lai · 2016 · F1000Research
  59. Advances in understanding and treating diabetic kidney disease: focus on tubulointerstitial inflammation mechanisms
    Chengren Xu, Xiaowen Ha, Shufen Yang, Xuefei Tian, Hong Jiang · 2023 · Frontiers in Endocrinology
  60. Patterns of Toll-Like Receptor Expressions and Inflammatory Cytokine Levels and Their Implications in the Progress of Insulin Resistance and Diabetic Nephropathy in Type 2 Diabetic Patients
    Rofyda H. Aly, Amr E. Ahmed, Walaa Gamal Hozayen, Alaa Mohamed Rabea, Tarek Mohamed Ali, Ahmad El Askary, Osama M. Ahmed · 2020 · Frontiers in Physiology
  61. Immunesenescence: A Predisposing Risk Factor for the Development of COVID-19?
    Jon Hazeldine, Janet M. Lord · 2020 · Frontiers in Immunology
  62. Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes
    Theodora Szasz, Camilla Ferreira Wenceslau, Beth Burgess, Kênia Pedrosa Nunes, Robert Clinton Webb · 2016 · Diabetes
  63. Role of Leptin and SOCS3 in Inhibiting the Type I Interferon Response During Obesity
    Elí Terán-Cabanillas, Jesús Hernández · 2016 · Inflammation
  64. Microbial Host Interactions and Impaired Wound Healing in Mice and Humans: Defining a Role for BD14 and NOD2
    Helen Williams, Laura Campbell, Rachel A Crompton, Gurdeep Singh, Brian J. McHugh, Donald J. Davidson, Andrew J. McBain, Sheena Margaret Cruickshank, Matthew J. Hardman · 2018 · Journal of Investigative Dermatology
  65. Small fragments of hyaluronan are increased in individuals with obesity and contribute to low-grade inflammation through TLR-mediated activation of innate immune cells
    Mónica Romo, Cristina López‐Vicario, Noelia Pérez, Mireia Casulleras, Ana Isabel Martínez-Puchol, Belén Sánchez, Roger Flores‐Costa, José Alcaraz‐Quiles, Marta Duran‐Güell, Ainitze Ibarzábal et al. · 2022 · International Journal of Obesity
  66. How dysregulation of the immune system promotes diabetes mellitus and cardiovascular risk complications
    Diane Girard, Claire Vandiedonck · 2022 · Frontiers in Cardiovascular Medicine
  67. Adipose Tissue in Persons With HIV Is Enriched for CD4+ T Effector Memory and T Effector Memory RA+ Cells, Which Show Higher CD69 Expression and CD57, CX3CR1, GPR56 Co-expression With Increasing Glucose Intolerance
    Celestine N. Wanjalla, Wyatt J. McDonnell, Louise D. Barnett, Joshua D. Simmons, Briana D. Furch, Morgan C. Lima, Beverly O. Woodward, Run Fan, Ye Fei, Paxton G. Baker et al. · 2019 · Frontiers in Immunology
  68. Thermodynamic contributions of single internal rA·dA, rC·dC, rG·dG and rU·dT mismatches in RNA/DNA duplexes
    Norman E. Watkins, William J. Kennelly, Mike J. Tsay, Astrid Tuin, Lara Swenson, Nana Lee, Svetlana V Morosyuk, Donald A. Hicks, John SantaLucia · 2010 · Nucleic Acids Research
  69. Toll-like receptors and inflammation in metabolic neuropathy; a role in early versus late disease?
    Sarah E. Elzinga, Benjamin J. Murdock, Kai Guo, J.M. Hayes, Maegan A. Tabbey, Junguk Hur, Eva L. Feldman · 2019 · Experimental Neurology
  70. Low Levels of Lipopolysaccharide Modulate Mitochondrial Oxygen Consumption in Skeletal Muscle
    Madlyn I. Frisard, Yaru Wu, Ryan P. McMillan, Kevin A. Voelker, Kristin A. Wahlberg, Angela S. Anderson, Nabil E. Boutagy, Kyle Resendes, Éric Ravussin, Matthew W. Hulver · 2014 · Metabolism
  71. Involvement of HMGB1 mediated signalling pathway in diabetic retinopathy: evidence from type 2 diabetic rats and ARPE-19 cells under diabetic condition
    Xiao-Li Chen, Xuedong Zhang, Ying-Yuan Li, Xue-Mei Chen, Derong Tang, Ruijin Ran · 2013 · British Journal of Ophthalmology
  72. The Inhibitory Effect of Rapamycin on Toll Like Receptor 4 and Interleukin 17 in the Early Stage of Rat Diabetic Nephropathy
    Ruichao Yu, Hong Bo, Vincenzo Villani, Philip John Spencer, Ping Fu · 2016 · Kidney & Blood Pressure Research
  73. TLR4 triggered complex inflammation in human pancreatic islets
    Wei He, Osmond D. Rebello, Rocco Savino, Rosa Terracciano, Carole Schuster, Béatrice Guardiola, Kathrin Maedler · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  74. A Possible Link of Gut Microbiota Alteration in Type 2 Diabetes and Alzheimer’s Disease Pathogenicity: An Update
    Alam, Mohammad, Alam, Qamre, Kamal, Mohammad, Abuzenadah, Adel, Haque, Absarul · 2014 · CNS & Neurological Disorders - Drug Targets
  75. Biomarkers and immune-modulating therapies for Type 2 diabetes
    Barbara Brooks‐Worrell, Radhika Rao Narla, Jerry P. Palmer · 2012 · Trends in Immunology
  76. The expression of genes involved in NF-κB activation in peripheral blood mononuclear cells of patients with gestational diabetes
    Mariusz Kuźmicki, Beata Telejko, Natalia Wawrusiewicz‐Kurylonek, Danuta Lipińska, Justyna Pliszka, Julisz Wilk, Anna Zielińska, Justyna Skibicka, Jacek Szamatowicz, Adam Jacek Kretowski et al. · 2012 · European Journal of Endocrinology
  77. PGC1αActivators Mitigate Diabetic Tubulopathy by Improving Mitochondrial Dynamics and Quality Control
    So‐Young Lee, Jun Mo Kang, Dong-Jin Kim, Seon Hwa Park, Hye Yun Jeong, Yu Ho Lee, Yang‐Gyun Kim, Dong Ho Yang, Sang Ho Lee · 2017 · Journal of Diabetes Research
  78. TLR4 gene polymorphisms: evidence for protection against type 2 diabetes but not for diabetes-associated ischaemic heart disease
    Anastassios C. Manolakis, Andreas N. Kapsoritakis, Elisavet K. Tiaka, Andreas Sidiropoulos, A. Gerovassili, Μαρία Σάτρα, Dimitra N. Vamvakopoulou, Fotios D. Tsiopoulos, N. Papanas, John S. Skoularigis et al. · 2011 · European Journal of Endocrinology
  79. Hyperglycemia Induces Inflammatory Response of Human Macrophages to CD163-Mediated Scavenging of Hemoglobin-Haptoglobin Complexes
    Laura Matuschik, Vladimir Riabov, Christina Schmuttermaier, Tatyana N. Sevastyanova, Christel Weiß, Harald Klüter, Julia G. Kzhyshkowska · 2022 · International Journal of Molecular Sciences
  80. High Mobility Group Box-1: A Missing Link between Diabetes and Its Complications
    Han Wu, Zheng Chen, Jun Xie, Lina Kang, Lian Wang, Biao Xu · 2016 · Mediators of Inflammation
  81. Metformin alleviates hyperglycemia-induced apoptosis and differentiation suppression in osteoblasts through inhibiting the TLR4 signaling pathway
    Lifeng Zheng, Ximei Shen, Junjian Ye, Yun Xie, Sunjie Yan · 2018 · Life Sciences
  82. Diet-Induced Alterations in Gut Microflora Contribute to Lethal Pulmonary Damage in TLR2/TLR4-Deficient Mice
    Yewei Ji, Shengyi Sun, Julia K. Goodrich, Hana Kim, Angela C. Poole, Gerald E. Duhamel, Ruth E. Ley, Ling Qi · 2014 · Cell Reports
  83. Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulin.
    H. Jang, Hae-Su Kim, D. Hwang, M. Quon, Jeong-a Kim · 2013 · American Journal of Physiology. Endocrinology and Metabolism
  84. Therapeutic Opportunities in Damage-Associated Molecular Pattern-Driven Metabolic Diseases
    Irma García‐Martinez, Mohamed E. Shaker, Wajahat Zafar Mehal · 2015 · Antioxidants and Redox Signaling
  85. The Opening of ATP-Sensitive K+ Channels Protects H9c2 Cardiac Cells Against the High Glucose-Induced Injury and Inflammation by Inhibiting the ROS-TLR4-Necroptosis Pathway
    Weijie Liang, Meiji Chen, Dongdan Zheng, Jianhao Li, Mingcai Song, Wenzhu Zhang, Jianqiang Feng, Jun Lan · 2017 · Cellular Physiology and Biochemistry
  86. Gene Expression Profiling Identifies Downregulation of the Neurotrophin-MAPK Signaling Pathway in Female Diabetic Peripheral Neuropathy Patients
    Lin Luo, Wenhua Zhou, Jiang-Jia Cai, Mei Feng, Mi Zhou, Supei Hu, Jin Xu, Lindan Ji · 2017 · Journal of Diabetes Research
  87. Lysophosphatidic acid receptor 1 inhibitor, AM095, attenuates diabetic nephropathy in mice by downregulation of TLR4/NF-κB signaling and NADPH oxidase
    Jong Han Lee, Mithun Kumer Sarker, Hojung Choi, Dongyun Shin, Donghee Kim, Hee‐Sook Jun · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  88. TNF-α in Combination with Palmitate Enhances IL-8 Production via The MyD88- Independent TLR4 Signaling Pathway: Potential Relevance to Metabolic Inflammation
    Amal Hasan, Nadeem Akhter, Areej Al-Roub, Reeby Thomas, Shihab Kochumon, Ajit Wilson, Merin Koshy, Ebaa Al‐Ozairi, Fahd Al‐Mulla, Rasheed Ahmad · 2019 · International Journal of Molecular Sciences
  89. High Mobility Group Box-1 and Diabetes Mellitus Complications: State of the Art and Future Perspectives
    Federico Biscetti, Maria Margherita Rando, Elisabetta Nardella, Andrea Leonardo Cecchini, Giovanni Pecorini, Raffaele Landolfi, Andrea Flex · 2019 · International Journal of Molecular Sciences
  90. BET protein inhibitor apabetalone (RVX-208) suppresses pro-inflammatory hyper-activation of monocytes from patients with cardiovascular disease and type 2 diabetes
    Sylwia Wasiak, Kim E. Dzobo, Brooke D. Rakai, Yannick Kaiser, Miranda Versloot, Mahnoush Bahjat, Stephanie C. Stotz, Li Fu, Michael Sweeney, Jan O. Johansson et al. · 2020 · Clinical Epigenetics
  91. Expression of Toll-Like Receptor 2 in Glomerular Endothelial Cells and Promotion of Diabetic Nephropathy by Porphyromonas gingivalis Lipopolysaccharide
    Yoshihiko Sawa, Shunsuke Takata, Yuji Hatakeyama, Hiroyuki Tako Ishikawa, Eichi Tsuruga · 2014 · PLoS ONE
  92. Insoluble and Soluble Dietary Fibers from Kiwifruit (Actinidia deliciosa) Modify Gut Microbiota to Alleviate High-Fat Diet and Streptozotocin-Induced TYPE 2 Diabetes in Rats
    Kunli Wang, Yuxiao Wang, Si Chen, Junlian Gu, Yuanying Ni · 2022 · Nutrients
  93. Endotoxemia of Metabolic Syndrome: A Pivotal Mediator of Meta-Inflammation
    Ishwarlal Jialal, Uthra Rajamani · 2014 · Metabolic Syndrome and Related Disorders
  94. High Concentration of Insulin Promotes Apoptosis of Primary Cultured Rat Ovarian Granulosa Cells Via Its Increase in Extracellular HMGB1
    Xiaorong Ni, Zhou-Jun Sun, Guo-Hua Hu, Ronghui Wang · 2014 · Reproductive Sciences
  95. The Effects of Antidepressants “Fluoxetine and Imipramine” on Vascular Abnormalities and Toll Like Receptor-4 Expression in Diabetic and Non-Diabetic Rats Exposed to Chronic Stress
    Mohamed Z. Habib, Safaa Mohammed Shaker, Nesreen Elgayar, Sawsan Aboul‐Fotouh · 2015 · PLoS ONE
  96. Effect of punicalagin on multiple targets in streptozotocin/high-fat diet-induced diabetic mice
    Dan Jin, Baiyu Zhang, Qiaoling Li, Jingjing Tu, Benhong Zhou · 2020 · Food & Function
  97. Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1
    Zhen Guo, Yixuan Zhang, Chang Liu, Ji Youn Youn, Hua “Linda” Cai · 2021 · Diabetes
  98. Endotoxaemia resulting from decreased serotonin tranporter (5-HTT) function: A reciprocal risk factor for depression and insulin resistance?
    Помыткин Игорь Анатольевич, Brandon H. Cline, Daniel C. Anthony, Harry W.M. Steinbusch, Klaus‐Peter Lesch, Tatyana V. Strekalova · 2014 · Behavioural Brain Research
  99. Metainflammation in Diabetic Coronary Artery Disease: Emerging Role of Innate and Adaptive Immune Responses
    Vivekanandhan Aravindhan, Madhumitha Haridoss · 2016 · Journal of Diabetes Research
  100. Cutaneous Nod2 Expression Regulates the Skin Microbiome and Wound Healing in a Murine Model
    Helen Williams, Rachel A Crompton, Helen A. Thomason, Laura Campbell, Gurdeep Singh, Andrew J. McBain, Sheena Margaret Cruickshank, Matthew J. Hardman · 2017 · Journal of Investigative Dermatology