Effect of Empagliflozin on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial (E-LIFT Trial)
Kuchay, Mohammad Shafi, Krishan, Sonal, Mishra, Sunil Kumar, Farooqui, Khalid Jamal, Singh, Manish Kumar, Wasir, Jasjeet Singh, Bansal, Beena, Kaur, Parjeet, Jevalikar, Ganesh, Gill, Harmendeep Kaur, Choudhary, Narendra Singh, Mithal, Ambrish·2018·Diabetes Care
Cited by (657)
Items 101–200 of 657
- Antidiabetic Therapy in the Treatment of Nonalcoholic SteatohepatitisYoshio Sumida, Masashi Yoneda, Katsutoshi Tokushige, Miwa Kawanaka, Hideki Fujii, Masato Yoneda, Kento Imajo, Hirokazu Takahashi, Yuichiro Eguchi, Masafumi Ono et al. · 2020 · International Journal of Molecular Sciences
- Gut-pancreas-liver Axis as a target for treatment of NAFLD/NASHSvegliati-Baroni, Gianluca, Patrício, Bárbara, Lioci, Gessica, Macedo, Maria Paula, Gastaldelli, Amalia · 2020 · International Journal of Molecular Sciences
- SGLT2 Inhibition for Cardiovascular Diseases, Chronic Kidney Disease, and NAFLDMoein Ala · 2021 · Endocrinology
- Antidiabetic Drugs and Statins in Nonalcoholic Fatty Liver DiseaseSneha Kothari, Hiteshi Dhami-Shah, Samir R. Shah · 2019 · Journal of Clinical and Experimental Hepatology
- Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndromeMengyuan Ge, Judith Molina, Jin‐Ju Kim, Shamroop Kumar Mallela, Anis Ahmad, Javier Varona Santos, Hassan Al‐Ali, Alla V. Mitrofanova, Kumar Sharma, Flavia Fontanesi et al. · 2023 · eLife
- Effect of sodium‐glucose cotransporter 2 inhibitor, empagliflozin, and α‐glucosidase inhibitor, voglibose, on hepatic steatosis in an animal model of type 2 diabetesJW Kim, Ye‐Jee Lee, Young‐Hye You, Min Kyong Moon, Kun‐Ho Yoon, Yu‐Bae Ahn, Seung‐Hyun Ko · 2018 · Journal of Cellular Biochemistry
- Hepatocyte-specific fibroblast growth factor 21 overexpression ameliorates high-fat diet-induced obesity and liver steatosis in miceKota Yano, Kanji Yamaguchi, Yuya Seko, Shinya Okishio, Hiroshi Ishiba, Nozomi Tochiki, Aya Takahashi, Seita Kataoka, Keiichiro Okuda, Yu Xin Liu et al. · 2021 · Laboratory Investigation
- Sodium-Glucose Co-Transporter 2 Inhibitors for Non-Alcoholic Fatty Liver Disease in Asian Patients With Type 2 Diabetes: A Meta-AnalysisChloe Wong, Clyve Yu Leon Yaow, Cheng Han Ng, Yip Han Chin, Yi Fen Low, Amanda Yuan Ling Lim, Mark Dhinesh Muthiah, Chin Meng Khoo · 2021 · Frontiers in Endocrinology
- SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activationLiu, Wenhui, You, Danming, Lin, Jiayang, Zou, Huren, Zhang, Lei, Luo, Shenjian, Yuan, Youwen, Wang, Zhiyi, Qi, Jingwen, Wang, Weiwei et al. · 2024 · Cell Metabolism
- Effects of sodium-glucose co-transporter 2 inhibitors on liver parameters and steatosis: a meta-analysis of randomized clinical trialsCoelho, Francisca dos Santos, Borges‐Canha, Marta, von Hafe, Madalena, Neves, João Sérgio, Vale, Catarina, Leite, Ana Rita, Carvalho, Davide, Leite‐Moreira, Adelino · 2021 · Diabetes/Metabolism Research and Reviews
- Effect of dapagliflozin on liver and pancreatic fat in patients with type 2 diabetes and non-alcoholic fatty liver diseaseMengran Shi, Hao Zhang, Wei Wang, Xiao Zhang, Jiawei Liu, Qixian Wang, Yuan Wang, Chunlin Zhang, Xiaoqin Guo, Qiao Qiao et al. · 2023 · Journal of Diabetes and its Complications
- Glucagon-Like Peptide 1 Receptor Agonists and Sodium–Glucose Cotransporter 2 Inhibitors and Risk of Nonalcoholic Fatty Liver Disease Among Patients With Type 2 DiabetesRicheek Pradhan, Hui Yin, Oriana Hoi Yun Yu, Laurent Azoulay · 2022 · Diabetes Care
- Risk of hepatic events associated with use of sodium-glucose cotransporter-2 inhibitors versus glucagon-like peptide-1 receptor agonists, and thiazolidinediones among patients with metabolic dysfunction-associated steatotic liver diseaseSungho Bea, Hwa Yeon Ko, Jae Hyun Bae, Young Min Cho, Yoosoo Chang, Seungho Ryu, Christopher D. Byrne, Ju‐Young Shin · 2024 · Gut
- How Do SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors and GLP-1 (Glucagon-Like Peptide-1) Receptor Agonists Reduce Cardiovascular Outcomes?Matthew M.Y. Lee, Mark Colquhoun Petrie, John J.V. McMurray, Naveed A. Sattar · 2020 · Arteriosclerosis Thrombosis and Vascular Biology
- Impact of sodium glucose cotransporter-2 inhibitors on liver steatosis/fibrosis/inflammation and redox balance in non-alcoholic fatty liver diseaseFrancesco Bellanti, Aurelio Lo Buglio, Michał Dobrakowski, Aleksandra Kasperczyk, Sławomir Kasperczyk, Palok Aich, Shivaram Prasad Singh, Gaetano Serviddio, Gianluigi Vendemiale · 2022 · World Journal of Gastroenterology
- Antifibrotic effect and long‐term outcome of SGLT2 inhibitors in patients with NAFLD complicated by diabetes mellitusTaeang Arai, Masanori Atsukawa, Akihito Tsubota, Shigeru Mikami, Haruki Uojima, Keiichiro Yoshikata, Hiroki Ono, Tadamichi Kawano, Yuji Yoshida, Tomohide Tanabe et al. · 2022 · Hepatology Communications
- Empagliflozin protects mice against diet-induced obesity, insulin resistance and hepatic steatosisBernhard Radlinger, Claudia Ress, Sabrina Folie, Karin Salzmann, Ana Lechuga, Bernhard Weiss, Willi Salvenmoser, Michael Graber, Jakob Hirsch, Johannes Holfeld et al. · 2022 · Diabetologia
- Concurrent nonalcoholic fatty liver disease and type 2 diabetes: diagnostic and therapeutic considerationsMarco A. Arrese, Francisco Barrera M., Nicolás Triantafilo, Juan Pablo Arab · 2019 · Expert Review of Gastroenterology & Hepatology
- Nonalcoholic Fatty Liver Disease and Diabetes: Part II: TreatmentKyung‐Soo Kim, Byung‐Wan Lee, Yong Jin Kim, Dae Ho Lee, Bong Soo, Cheol‐Young Park · 2019 · Diabetes & Metabolism Journal
- Novel Therapies for Alport SyndromeEfren Chavez, Juanly Rodriguez, Yelena R. Drexler, Alessia Fornoni · 2022 · Frontiers in Medicine
- Empagliflozin versus sitagliptin for ameliorating intrahepatic lipid content and tissue‐specific insulin sensitivity in patients with early‐stage type 2 diabetes with non‐alcoholic fatty liver disease: A prospective randomized studyShigenori Hiruma, Fumika Shigiyama, Naoki Kumashiro · 2023 · Diabetes Obesity and Metabolism
- Effects of empagliflozin on liver fat in patients with metabolic dysfunction–associated steatotic liver disease without diabetes mellitus: A randomized, double-blind, placebo-controlled trialKa Shing Cheung, Ho Yu Ng, Rex Wan Hin Hui, Lok Ka Lam, Lung‐Yi Mak, Yuen Chi Ho, Jing Tong Tan, Esther W. Chan, Wai‐Kay Seto, Man‐Fung Yuen et al. · 2024 · Hepatology
- NRF-2 and nonalcoholic fatty liver diseaseArturo Solano-Urrusquieta, José A. Morales‐González, Graciela Castro‐Narro, Eira Cerda Reyes, Perla Denice Flores-Rangel, Raul Fierros-Oceguera · 2020 · Annals of Hepatology
- Combined exenatide and dapagliflozin has no additive effects on reduction of hepatocellular lipids despite better glycaemic control in patients with type 2 diabetes mellitus treated with metformin: EXENDA , a 24‐week, prospective, randomized, placebo‐controlled pilot trialJürgen Harreiter, Ivica Just, Michael Leutner, Magdalena Bastian, Helmut Brath, Christian Schelkshorn, Radka Klepochová, Martin Krššák, Alexandra Kautzky‐Willer · 2021 · Diabetes Obesity and Metabolism
- Empagliflozin ameliorates ethanol-induced liver injury by modulating NF-κB/Nrf-2/PPAR-γ interplay in miceAmir Mohamed Abdelhamid, Ahmed R. El‐Sheakh, Rania Ramadan Abdelaziz, Ghada Mohamed Suddek · 2020 · Life Sciences
- SGLT2 inhibitors for improving hepatic fibrosis and steatosis in non-alcoholic fatty liver disease complicated with type 2 diabetes mellitus: a systematic reviewDwinata, Michael, Putera, David, Hasan, Irsan, Raharjo, Monica · 2020 · Clinical and Experimental Hepatology
- Metabolic syndrome and its association with nonalcoholic steatohepatitisBril, Fernando, Sanyal, Arun, Cusi, Kenneth · 2023 · Clinics in Liver Disease
- The metabolic triad of non‐alcoholic fatty liver disease, visceral adiposity and type 2 diabetes: Implications for treatmentBertrand Cariou · 2022 · Diabetes Obesity and Metabolism
- Antidiabetic Drugs in NAFLD: The Accomplishment of Two Goals at Once?Matteo Tacelli, Ciro Celsa, Bianca Magro, Aurora Giannetti, Grazia Pennisi, Federica Spatola, Salvatore Petta · 2018 · Pharmaceuticals
- Effect of orlistat on liver fat content in patients with nonalcoholic fatty liver disease with obesity: assessment using magnetic resonance imaging-derived proton density fat fractionJunzhao Ye, Yanqin Wu, Fuxi Li, Tingfeng Wu, Congxiang Shao, Yansong Lin, Wei Wang, Shi‐Ting Feng, Bihui Zhong · 2019 · Therapeutic Advances in Gastroenterology
- A diabetologist’s perspective of non‐alcoholic steatohepatitis (NASH): Knowledge gaps and future directionsKenneth J. Cusi · 2020 · Liver International
- Use of SGLT-2 Inhibitors in Patients with Type 2 Diabetes Mellitus and Abdominal Obesity: An Asian Perspective and Expert RecommendationsWayne Huey‐Herng Sheu, Siew Pheng Chan, Bien J. Matawaran, Chaicharn Deerochanawong, Ambrish Mithal, Juliana C.N. Chan, Ketut Suastika, Chin Meng Khoo, Huu Man Nguyen, Linong Ji et al. · 2020 · Diabetes & Metabolism Journal
- Antidiabetic Medications for Type 2 Diabetics with Nonalcoholic Fatty Liver Disease: Evidence From a Network Meta-Analysis of Randomized Controlled TrialsCheng Han Ng, Snow Yunni Lin, Yip Han Chin, Ming Hui Lee, Nicholas L. X. Syn, Xin Lei Goh, Jin Hean Koh, Jingxuan Quek, Darren Jun Hao Tan, Shao Feng Mok et al. · 2021 · Endocrine Practice
- The Gut Microbiome and Ferroptosis in MAFLDJie Ji, Liwei Wu, Jue Wei, Jianye Wu, Chuanyong Guo · 2022 · Journal of Clinical and Translational Hepatology
- Effects of SGLT-2 inhibitors on adipose tissue distribution in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trialsXianghong Wang, Niujian Wu, Chuanchuan Sun, Donghua Jin, Hongyun Lu · 2023 · Diabetology & Metabolic Syndrome
- Predisposing factors for the development of diabetic ketoacidosis with lower than anticipated glucose levels in type 2 diabetes patients on SGLT2-inhibitors: a reviewBamgboye, Adeboye Olakunle, Oni, Isaac Oluwadamilare, Collier, Andrew · 2021 · European Journal of Clinical Pharmacology
- SGLT2 Inhibitors in Liver PatientsHsiang, John Chen, Wong, Vincent Wai-Sun · 2020 · Clinical Gastroenterology and Hepatology
- Effects of sodium-glucose co-transporter 2 inhibitors on liver fibrosis in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus: An updated meta-analysis of randomized controlled trialsZijie Jin, Yan Yuan, Zheng Chen, Shijian Liu, Hongbo Weng · 2023 · Journal of Diabetes and its Complications
- Effect of Weight Loss Medications on Hepatic Steatosis and Steatohepatitis: A Systematic ReviewChelsea S. Pan, Takara Leah Stanley · 2020 · Frontiers in Endocrinology
- Malaysian Society of Gastroenterology and Hepatology consensus statement on metabolic dysfunction‐associated fatty liver diseaseWah‐Kheong Chan, Soek-Siam Tan, Siew-Pheng Chan, Yeong Yeh Lee, Hoi‐Poh Tee, Sanjiv Mahadeva, Khean‐Lee Goh, Anis Safura Ramli, Feisul Idzwan Mustapha, Nik Ritza Kosai et al. · 2022 · Journal of Gastroenterology and Hepatology
- Anti-obesity Medications for the Management of Nonalcoholic Fatty Liver DiseaseStergios A. Pοlyzos, Dimitrios G. Goulis, Όλγα Γιουλεμέ, Georgios S. Germanidis, Antonis Goulas · 2022 · Current Obesity Reports
- Cardiometabolic and renal benefits of sodium–glucose cotransporter 2 inhibitorsYong‐ho Lee, Soo Kyung Lim, Melanie Jane Davies · 2025 · Nature Reviews Endocrinology
- A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic SteatohepatitisSurosree Ganguli, Peter Deleeuw, Sanjaya Kumar Satapathy · 2019 · Hepatic Medicine Evidence and Research
- SGLT2 inhibitors in patients with type 2 diabetes with non-alcoholic fatty liver diseases: an umbrella review of systematic reviewsShao, Shih-Chieh, Kuo, Liang-Tseng, Chien, Rong-Nan, Hung, Ming-Jui, Lai, Edward Chia-Cheng · 2020 · BMJ Open Diabetes Research & Care
- Liver-targeting drugs and their effect on blood glucose and hepatic lipidsAmalia Gastaldelli, Norbert Stefan, Hans‐Ulrich Häring · 2021 · Diabetologia
- The Impact of an SGLT2 Inhibitor versus Ursodeoxycholic Acid on Liver Steatosis in Diabetic PatientsSahar Hossam El-Hini, Engy A. Wahsh, Ahmed Abdullah Elberry, Nadia Farouk El Ameen, Ahmed Abdel Fadil Saedii, Shereen Mahmoud Refaie, Asmaa A. Elsayed, Hoda Rabea · 2022 · Pharmaceuticals
- MASLD development: From molecular pathogenesis toward therapeutic strategiesZhu Yang, Jiahui Zhao, Kexin Xie, Chengwei Tang, Can Gan, Jinhang Gao · 2025 · Chinese Medical Journal
- Effects of antidiabetic agents on steatosis and fibrosis biomarkers in type 2 diabetes: A real‐world data analysisSanto Colosimo, Federico Ravaioli, Maria Letizia Petroni, Lucia Brodosi, Francesca Marchignoli, Francesca Alessandra Barbanti, Anna Simona Sasdelli, Giulio Marchesini, Loris Pironi · 2021 · Liver International
- Expert Opinion: Optimum Clinical Approach to Combination-Use of SGLT2i + DPP4i in the Indian Diabetes SettingManoj D. Chadha, Ashok Kumar Das, Prasun Deb, Kalyan Kumar Gangopadhyay, Shashank Joshi, Jothydev Kesavadev, RAJIV R. KOVIL, Surender Kumar, Anoop Misra, Viswanathan Mohan · 2022 · Diabetes Therapy
- The Effects of Sodium-Glucose Cotransporter 2-Inhibitors on Steatosis and Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease or Steatohepatitis and Type 2 Diabetes: A Systematic Review of Randomized Controlled TrialsIoana-Cristina Bica, Roxana Adriana Stoica, Teodor Salmen, Andrej Janež, Špela Volčanšek, Djordje S. Popovic, Emir M. Muzurović, Manfredi Rizzo, Anca Pantea Stoian · 2023 · Medicina
- SGLT2 Inhibitors as the Most Promising Influencers on the Outcome of Non-Alcoholic Fatty Liver DiseaseLuigi Mirarchi, Simona Amodeo, Roberto Citarrella, Anna Licata, Maurizio Soresi, Lydia Giannitrapani · 2022 · International Journal of Molecular Sciences
- Effects of a Combination of Empagliflozin Plus Metformin vs. Metformin Monotherapy on NAFLD Progression in Type 2 Diabetes: The IMAGIN Pilot StudyAlfredo Caturano, Raffaele Galiero, Giuseppe Loffredo, Erica Vetrano, Giulia Medicamento, Carlo Acierno, Luca Rinaldi, Aldo Marrone, Teresa Salvatore, Marcellino Monda et al. · 2023 · Biomedicines
- Synergistic association of sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver diseaseXianhua Mao, Xinrong Zhang, Leslie Yeeman Kam, Nicholas Chien, Rongtao Lai, Ka Shing Cheung, Man‐Fung Yuen, Ramsey C Cheung, Wai‐Kay Seto, Mindie H. Nguyen · 2024 · Gut
- New anti-diabetic agents for the treatment of non-alcoholic fatty liver disease: a systematic review and network meta-analysis of randomized controlled trialsTanawan Kongmalai, Varalak Srinonprasert, Thunyarat Anothaisintawee, Pinkawas Kongmalai, Gareth J. McKay, John Attia, Ammarin Thakkinstian · 2023 · Frontiers in Endocrinology
- The interplay between nonalcoholic fatty liver disease and atherosclerotic cardiovascular diseaseFinney, Alexandra C., Das, Sandeep, Kumar, Dhananjay, McKinney, M. Peyton, Cai, Bishuang, Yurdagul, Arif, Rom, Oren · 2023 · Frontiers in Cardiovascular Medicine
- Sodium-glucose cotransporter 2 (SGLT-2) inhibitors and microvascular outcomes in patients with type 2 diabetes: systematic review and meta-analysisDorsey-Treviño, E. G., González-González, J. G., Alvarez-Villalobos, N., González-Nava, V., Contreras-Garza, B. M., Díaz González-Colmenero, A., Rodríguez-Tamez, G., Barrera-Flores, F. J., Farrell, A. M., Montori, V. M. et al. · 2020 · Journal of Endocrinological Investigation
- Comparative efficacy of 5 sodium-glucose cotransporter protein-2 (SGLT-2) inhibitor and 4 glucagon-like peptide-1 (GLP-1) receptor agonist drugs in non-alcoholic fatty liver disease: A GRADE-assessed systematic review and network meta-analysis of randomized controlled trialsYunpeng Gu, Lei Sun, Wei Zhang, Tingting Kong, Run Zhou, Yining He, Chaohua Deng, Luping Yang, Jianing Kong, Yutong Chen et al. · 2023 · Frontiers in Pharmacology
- Association of metabolic-dysfunction associated steatotic liver disease with polycystic ovary syndromeQiuyu Xu, Jie Zhang, Yan Lu, Ling Ying Wu · 2024 · iScience
- Safety and tolerability of empagliflozin in East Asian patients with type 2 diabetes: Pooled analysis of phase I– III clinical trialsDaisuke Yabe, Atsutaka Yasui, Linong Ji, Moon‐Kyu Lee, Ronald C.W., Tien‐Jyun Chang, Tomoo Okamura, Cordula Zeller, Stefan Kaspers, Jisoo Lee et al. · 2018 · Journal of Diabetes Investigation
- Efficacy and Safety of Empagliflozin on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-AnalysisYuyuan Zhang, Xiaobo Liu, Huazhu Zhang, Xuechang Wang · 2022 · Frontiers in Endocrinology
- Non-Invasive Measurement of Hepatic Fibrosis by Transient Elastography: A Narrative ReviewLuca Rinaldi, Chiara Giorgione, Andrea Mormone, Francesca Esposito, Michele Rinaldi, Massimiliano Berretta, Raffaele Marfella, Ciro Pasquale Romano · 2023 · Viruses
- Liver MR relaxometry at 3T – segmental normal T1 and T2* values in patients without focal or diffuse liver disease and in patients with increased liver fat and elevated liver stiffnessVerena Carola Obmann, Nando Mertineit, C. Marx, Annalisa Berzigotti, Lukas Ebner, Johannes T. Heverhagen, Andreas Christe, Adrian Thomas Huber · 2019 · Scientific Reports
- Effects of dapagliflozin on the serum levels of fibroblast growth factor 21 and myokines and muscle mass in Japanese patients with type 2 diabetes: A randomized, controlled trialHajime Yamakage, Masashi Tanaka, Takayuki Inoue, Shinji Odori, Toru Kusakabe, Noriko Satoh‐Asahara · 2019 · Journal of Diabetes Investigation
- Comparison of dapagliflozin and teneligliptin in nonalcoholic fatty liver disease patients without type 2 diabetes mellitus: a prospective randomized studyHiroshi Tobita, Tomotaka Yazaki, Masatoshi Kataoka, Satoshi Kotani, Akihiko Oka, Tsuyoshi Mishiro, Naoki Oshima, Kousaku Kawashima, Norihisa Ishimura, Kohji Naora et al. · 2020 · Journal of Clinical Biochemistry and Nutrition
- Comparative effectiveness of multiple different treatment regimens for nonalcoholic fatty liver disease with type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis of randomised controlled trialsManjun Deng, Yonghao Wen, Jingxin Yan, Yichen Fan, Zhixin Wang, Ruixia Zhang, Li Ren, Yinggui Ba, Haijiu Wang, Qian Lü et al. · 2023 · BMC Medicine
- Effects of dapagliflozin and/or insulin glargine on beta cell mass and hepatic steatosis in db/db miceKazuno Omori, Akinobu Nakamura, Hideaki Miyoshi, Kiyohiko Takahashi, Naoyuki Kitao, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, Ryo Takagi, Kanako C. Hatanaka et al. · 2019 · Metabolism
- Extrahepatic Manifestations of Nonalcoholic Fatty Liver DiseaseJulia J. Wattacheril · 2019 · Gastroenterology Clinics of North America
- Non-alcoholic Fatty Liver Disease and Diabetes MellitusGebran W. Khneizer, Syed Rizvi, Samer Gawrieh · 2020 · Advances in experimental medicine and biology
- Effects of empagliflozin on markers of liver steatosis and fibrosis and their relationship to cardiorenal outcomesSABINE KAHL, Anne Pernille Ofstad, Bernard Zinman, Christoph Wanner, Elke Schueler, Naveed A. Sattar, Silvio E. Inzucchi, Michael Roden · 2022 · Diabetes Obesity and Metabolism
- GLP-1 RAs and SGLT-2 Inhibitors for Insulin Resistance in Nonalcoholic Fatty Liver Disease: Systematic Review and Network Meta-AnalysisHongle Yan, Chunyi Huang, Xuejun Shen, Jufang Li, Shuyi Zhou, Weiping Li · 2022 · Frontiers in Endocrinology
- Impact of NAFLD and its pharmacotherapy on lipid profile and CVDZhenya Wang, Mao Ye, Xiao‐Jing Zhang, Peng Zhang, Jingjing Cai, Hongliang Li, Zhi‐Gang She · 2022 · Atherosclerosis
- Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese miceHaoya Yao, Yaoqing Wang, Xiao Zhang, Ping Li, Lin Shang, Xiaocui Chen, Jia Zeng · 2022 · Journal of Biological Chemistry
- Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathwayShaohan Huang, Beibei Wu, Yingzi He, Ruojun Qiu, Tian Yang, Shuo Wang, Yongzhen Lei, Hong Li, Fenping Zheng · 2023 · Hepatology Communications
- Effects of sodium-glucose co-transporter-2 (SGLT2) inhibitors on non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Ex quo et quo vadimus?Niki Katsiki, Nikolaos Perakakis, Christos Socrates Mantzoros · 2019 · Metabolism
- Non-alcoholic fatty liver disease in adults 2021: A clinical practice guideline of the Italian Association for the Study of the Liver (AISF), the Italian Society of Diabetology (SID) and the Italian Society of Obesity (SIO)Giulio Marchesini, Elisabetta Bugianesi, Patrizia Burra, Fabio Marra, Luca Miele, Anna Alisi, Piero Vajro, Mario Masarone, Salvatore Petta, Marcello Persico et al. · 2021 · Nutrition Metabolism and Cardiovascular Diseases
- Exploring the Role of SGLT2 Inhibitors in Cancer: Mechanisms of Action and Therapeutic OpportunitiesAparamita Pandey, Martín Alcaraz, Pasquale Saggese, Adriana Soto, Estefany Gomez, Shreya Jaldu, Jane Yanagawa, Claudio Scafoglio · 2025 · Cancers
- Key takeaways from the updated multidisciplinary European MASLD guidelinesPaul Horn, Frank Tacke · 2025 · eGastroenterology
- Type 2 diabetes in South AsiansAnoop Misra, Naveed A. Sattar, Amerta Ghosh, Mahmoud Nassar, Ranil Jayawardena, Ritesh Gupta · 2025 · BMJ
- Understanding MASLD — from molecular pathogenesis to cardiovascular risk: A concise review for the clinical cardiologistCarlo Ratti, Mattia Malaguti, Emanuele D’Aniello, Antonio Bellasi, Gianluca Sanna · 2025 · Atherosclerosis
- Pharmacological treatment of type 2 diabetes in elderly patients with heart failure: randomized trials and beyondAngela Sciacqua, Elena Succurro, Giuseppe Armentaro, Sofia Miceli, Daniele Pastori, Giuseppe Rengo, Giorgio Sesti · 2021 · Heart Failure Reviews
- Endpoints in NASH Clinical Trials: Are We Blind in One Eye?Amedeo Lonardo, Stefano Ballestri, Alessandro Mantovani, Giovanni Targher, Fernando Bril · 2024 · Metabolites
- From liver to hormones: The endocrine consequences of cirrhosisJuan Eduardo Quiroz Aldave, Elman Rolando Gamarra Osorio, María del Carmen Durand‐Vásquez, Luciana del Pilar Rafael-Robles, Jhean Gabriel Gonzáles Yovera, María Alejandra Quispe-Flores, Luis Alberto Concepción Urteaga, Alejandro Román-Gonzaléz, José Paz‐Ibarra, Marcio José Concepción‐Zavaleta · 2024 · World Journal of Gastroenterology
- Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitroTing Li, Ting Fang, Linxin Xu, Xiangyang Liu, Xiaoyu Li, Mei Xue, Xiaochen Yu, Bei Sun, Liming Chen · 2021 · Frontiers in Pharmacology
- Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASHNikolaos Perakakis, Pavlina Chrysafi, Michael Feigh, Sanne Skovgård Veidal, Christos Socrates Mantzoros · 2021 · International Journal of Molecular Sciences
- The role of anti-diabetic drugs in NAFLD. Have we found the Holy Grail? A narrative reviewMaria Zachou, Pagona Flevari, Narjes Nasiri Ansari, Constantinos Varytimiadis, Evangelos Kalaitzakis, Eva N. Kassi, Θεόδωρος Ανδρουτσάκος · 2023 · European Journal of Clinical Pharmacology
- Prevalence of hepatic steatosis in patients with type 2 diabetes and response to glucose-lowering treatments. A multicenter retrospective study in Italian specialist careMario Luca Morieri, Nicola Vitturi, Angelo Avogaro, Giovanni Targher, Gian Paolo Fadini, DARWIN-T2D Network of the Italian Diabetes Society, Agostino Consoli, Gloria Formoso, Giovanni Grossi, Achiropita Pucci et al. · 2021 · Journal of Endocrinological Investigation
- Impact of SGLT2 inhibitors in comparison with DPP4 inhibitors on ascites and death in veterans with cirrhosis on metforminSaad Saffo, David Edward Kaplan, Nadim Mahmud, Marina Serper, Binu V. John, Joseph S. Ross, Tamar Hamosh Taddei · 2021 · Diabetes Obesity and Metabolism
- Non-alcoholic fatty liver disease in adults 2021: A clinical practice guideline of the Italian Association for the Study of the Liver (AISF), the Italian Society of Diabetology (SID) and the Italian Society of Obesity (SIO)Giulio Marchesini, Elisabetta Bugianesi, Patrizia Burra, Fabio Marra, Luca Miele, Anna Alisi, Piero Vajro, Mario Masarone, Salvatore Petta, Marcello Persico et al. · 2021 · Digestive and Liver Disease
- Empagliflozin Reduces Liver Fat in Individuals With and Without DiabetesSiham Abdelgani, Ahmed Khattab, John M. Adams, Gozde Baskoy, Marissa Brown, Geoff Clarke, Olga Larvenenko, Ralph Anthony DeFronzo, Muhammad A Abdul‐Ghani · 2024 · Diabetes Care
- Management of diabetes mellitus in patients undergoing liver transplantationValeria Grancini, Veronica Resi, Eva Palmieri, Giuseppe Pugliese, Emanuela Orsi · 2019 · Pharmacological Research
- Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathwayJun Shirakawa, Kazuki Tajima, Tomoko Okuyama, Mayu Kyohara, Yu Togashi, Dario F. De Jesus, Giorgio Basile, Tatsuya Kin, Andrew M. James Shapiro, Rohit Kulkarni et al. · 2020 · Diabetologia
- NAFLD in type 2 diabetes mellitus: Still many challenging questionsSimona Cernea, Itamar Raz · 2020 · Diabetes/Metabolism Research and Reviews
- Clinical implications, diagnosis, and management of diabetes in patients with chronic liver diseasesWaihong Chung, Kittichai Promrat, Jack R. Wands · 2020 · World Journal of Hepatology
- Management of Diabetes in Candidates for Liver Transplantation and in Transplant RecipientsLucia Brodosi, Salvatore Petta, Maria Letizia Petroni, Giulio Marchesini, Maria Cristina Morelli · 2021 · Transplantation
- Effect of Sodium Glucose Co-Transporter 2 Inhibitors on Liver Fat Mass and Body Composition in Patients with Nonalcoholic Fatty Liver Disease and Type 2 Diabetes MellitusYoshitaka Arase, Koichi Shiraishi, Kazuya Anzai, Hirohiko Sato, Erika Teramura, Kota Tsuruya, Shunji Hirose, Ryuzo Deguchi, Masao Toyoda, Tetsuya Mine et al. · 2019 · Clinical Drug Investigation
- Pharmacotherapy for metabolic dysfunction-associated steatohepatitis: heart–liver co-managementXiaodong Zhou, Jeffrey Victor Lazarus, Chayakrit Krittanawong, Giovanni Targher, Christopher D. Byrne, Zobair M. Younossi, Frank Tacke, Qin‐Fen Chen, Christos Socrates Mantzoros, Herbert Tilg et al. · 2026 · The Lancet. Gastroenterology & hepatology
- Cardiovascular Disease in Nonalcoholic Steatohepatitis: Screening and ManagementHersh Shroff, Lisa B. VanWagner · 2020 · Current Hepatology Reports
- Myopathy Associated With Statins and SGLT2 – A Review of LiteratureRahul Gupta, Ryan Alcantara, Tarun Popli, Sugandhi Mahajan, Umair Tariq, Raman Dusaj, Aaqib Habib Malik · 2020 · Current Problems in Cardiology
- Gluconeogenesis, But Not Glycogenolysis, Contributes to the Increase in Endogenous Glucose Production by SGLT-2 InhibitionPeter S. Wolf, Paul Fellinger, Lorenz Pfleger, Hannes Beiglböck, Patrik Krumpolec, Chiara Barbieri, Amalia Gastaldelli, Jürgen Harreiter, Matthäus Metz, Thomas Scherer et al. · 2020 · Diabetes Care
- Effect of sodium-glucose cotransporter 2 inhibitor in patients with non-alcoholic fatty liver disease and type 2 diabetes mellitus: a propensity score-matched analysis of real-world dataTaeang Arai, Masanori Atsukawa, Akihito Tsubota, Shigeru Mikami, Hiroki Ono, Tadamichi Kawano, Yuji Yoshida, Tomohide Tanabe, Tomomi Okubo, Korenobu Hayama et al. · 2021 · Therapeutic Advances in Endocrinology and Metabolism