Extractable Insulin of Pancreas: Correlation with Pathological and Clinical Findings in Diabetic and Nondiabetic Cases
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Pancreatic insulin was almost undetectable in young people with diabetes, in contrast to a nearly ~50% reduction in older people with diabetes relative to nondiabetic controls.
“These experiments showed that pancreatic insulin was almost undetectable in young people with diabetes. This was in contrast to the nearly ~50% reduction observed in older people with diabetes relative to nondiabetic controls25.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [25]
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Pancreatic β‐cell mass in European subjects with type 2 diabetes
Rahier, J., Guiot, Y., Goebbels, R. M., Sempoux, C., & Henquin, J. C. (2008) · Diabetes, Obesity and Metabolism · doi:10.1111/j.1463-1326.2008.00969.x · Cited by 756 · see citing works
Davidson, M. B. (1979) · Metabolism · doi:10.1016/0026-0495(79)90024-6 · Cited by 411 · see citing works
100 years of insulin: celebrating the past, present and future of diabetes therapy
Sims, E. K., Carr, A. L. J., Oram, R. A., DiMeglio, L. A., & Evans-Molina, C. (2021) · Nature Medicine · doi:10.1038/s41591-021-01418-2 · Cited by 270 · see citing works
Ritzel, R. A., Veldhuis, J. D., & Butler, P. C. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021250 · Cited by 56 · see citing works
- Authors
- Wrenshall, G. A., Bogoch, A., & Ritchie, R. C.
- Affiliations
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- Venue
- Diabetes
- Publisher
- American Diabetes Association
- Published
- 1952-03-01
- Volume
- 1
- Issue
- 2
- Pages
- 87-107
- ISSN
- 0012-1797 (ISSN-L)
- 1939-327X
- OpenAlex
- W2317686853
- Cited by
- 180
- References
- 0
- Citations by year
- 2023: 2 · 2022: 1 · 2021: 3 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2013: 2 · 2012: 2
- FWCI
- 17.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Pennsylvania
- Banting Research Foundation
- Topics
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- pancreas, insulin secretion, diabetes mellitus, pancreatic pathology, clinical features
- MeSH terms
- Diabetes Mellitus, Humans, Insulin, Pancreas
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