Cited by 42Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and LipoproteinsBirth, Development, and Health

Gestational Blood Glucose Levels in Normal and Potentially Diabetic Women Related to the Birth Weight of Their Infants

O'Sullivan, John B, Gellis, Sydney S, Tenney, Benjamin O, Mahan, Clare M·1966·Diabetes

Abstract

Data from 5,534 prenatal registrants who had blood glucose determinations following the ingestion of 50 gm. of glucose indicated that age is the only maternal factor of significance to resulting blood glucose levels when other variables are held fixed. The lack of a blood glucose—birth weight correlation in the general population was further explored with the demonstration that such a relationship exists among groups of potentially diabetic women. Overweight women giving birth to a large baby were found to have significantly higher mean blood glucose values. The overweight women with an infant of average birth weight or the normal weight women with a large baby had no such blood glucose elevation. These data imply that more accurate separation of either the overweight women or women giving birth to large babies into groups of special significance to future development of diabetes mellitus is possible.

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Crossref · 10.2337/diab.15.7.466

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  • In 1961 the incidence of gestational diabetes mellitus was estimated to be less than 1%, and it increased from 0.3% in 1979-1980 to 5.8% in 2008-2010.

    “While in 1961 the incidence of GDM was estimated to be less than 1% [49,50], it increased from 0.3% in 1979–1980 to 5.8% in 2008–2010 [51].”
  • Maternal obesity is a well-known independent risk factor for gestational diabetes mellitus.

    “Maternal obesity is a well-known, independent risk factor for GDM.”

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Authors
O'Sullivan, J. B., Gellis, S. S., Tenney, B. O., & Mahan, C. M.
Affiliations
  • Boston City Hospital Boston, Massachusetts, and the Diabetes Field Research Unit, Diabetes and Arthritis Program, Division of Chronic Diseases, Public Health Service, U.S. Department of Health, Education, and Welfare Brighton, Massachusetts
  • United States Public Health Service (US)
Venue
Diabetes
Published
1966-07-01
Volume
15
Issue
7
Pages
466-470
ISSN
  • 0012-1797 (ISSN-L)
  • 1939-327X
OpenAlex
W2011366584
Cited by
42
References
0
Citations by year
2022: 1 · 2020: 1 · 2018: 1 · 2017: 2
FWCI
10.94
Type
journal article
Language
en
Open access
closed
Locations
  • Diabetes (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Keywords
birth weight, maternal overweight, large for gestational age, diabetes risk, glucose tolerance, maternal age, prenatal screening, gestational diabetes mellitus
MeSH terms
Adult, Aging, Birth Weight, Blood Glucose, Female, Glucose Tolerance Test, Humans, Infant, Newborn, Obesity, Pregnancy, Pregnancy in Diabetics

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