Glucose Tolerance and Insulin Release, A Mathematical Approach: I. Assay of the Beta-cell Response After Oral Glucose Loading

From txshe dose-response relations between glucose and insulin after oral glucose loading, a reproducible parameter for beta-cell response was deduced. The main advantage of this parameter —corrected insulin response, defined as CIR = I · 100/G(G–70)— lies in it independence from the initial or r…