Use of the Diabetes Risk Score for Opportunistic Screening of Undiagnosed Diabetes and Impaired Glucose Tolerance
Abstract
Objective To evaluate an opportunistic screening strategy addressed to individuals with one or more cardiovascular risk factor, based on the Diabetes Risk Score (DRS) as the initial instrument, for the identification of individuals with type 2 diabetes or impaired glucose tolerance (IGT). Research design and methods The DRS, a simple self-administered questionnaire, was completed by individuals identified by general practitioners and presenting with one or more cardiovascular risk factor. All patients underwent a 2-h oral glucose tolerance test (OGTT). The optimal DRS cutoff was calculated by applying the receiver-operating characteristic curve. Results Overall, 1,377 individuals aged between 55 and 75 years received an OGTT and completed the DRS. Mean DRS values showed a marked variation according to glucose metabolism categories, as follows: 8.7 +/- 3.0 in normoglycemic individuals, 9.5 +/- 3.1 in individuals with impaired fasting glucose, 9.9 +/- 3.3 in individuals with IGT, and 12.0 +/- 3.5 in individuals with type 2 diabetes. The receiver-operating characteristic curve showed that, with a cutoff of 9, the sensitivity of DRS in detecting individuals with glucose abnormalities (type 2 diabetes or IGT) was 77% and the specificity 45%. The use of the DRS as an initial screening instrument, followed by the measurement of fasting blood glucose in individuals with a score > or =9 and by the OGTT in individuals with a fasting blood glucose between 5.6 and 6.9 mmol/l, would lead…
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FINDRISC is the most commonly evaluated diabetes risk score worldwide and has been recommended as the best available risk assessment tool for clinical practice by a systematic review.
“Moreover, FINDRISC is the most commonly evaluated diabetes risk score worldwide [17,18,19,20,21,22,23,24,25] and has been recommended as the best available risk assessment tool for use in the clinical practice by a systematic review [11].”
From A Novel Testing Model for Opportunistic Screening of Pre-Diabetes and Diabetes among U.S. Adults (2015) · cites this paper as [17]
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- Authors
- Franciosi, M., De Berardis, G., Rossi, M. C. E., Sacco, M., Belfiglio, M., Pellegrini, F., Tognoni, G., Valentini, M., Nicolucci, A., & for the IGLOO Study Group
- Affiliations
- From the Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, S. Maria Imbaro, Italy
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2005-05-01
- Volume
- 28
- Issue
- 5
- Pages
- 1187-1194
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2134472233
- Cited by
- 161
- References
- 22
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 8 · 2021: 7 · 2020: 12 · 2019: 8 · 2018: 5 · 2017: 7 · 2016: 10 · 2015: 11 · 2014: 9 · 2013: 10 · 2012: 7
- FWCI
- 5.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- diabetes risk score, opportunistic screening, type 2 diabetes, impaired glucose tolerance, cardiovascular risk factors, oral glucose tolerance test, fasting blood glucose, screening cut-off values, sensitivity and specificity, general practice
- MeSH terms
- Aged, Blood Glucose, Diabetes Mellitus, Type 2, Fasting, Female, Glucose Tolerance Test, Humans, Male, Mass Screening, Middle Aged, Prospective Studies, Surveys and Questionnaires, Risk Factors, Incidence, Prevalence, Glucose Intolerance, Risk Assessment
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