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Relationship Between β-Cell Mass and Fasting Blood Glucose Concentration in Humans
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“Furthermore, studies of obese patients (including non-diabetic, prediabetic and diabetic groups) reported an inverse relationship between blood glucose levels and β-cell volume below a certain threshold [8], illustrating the importance of β-cell mass as a central factor determining insulin secretory capacity.”
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Metadata
- Authors
- Ritzel, R. A., Butler, A. E., Rizza, R. A., Veldhuis, J. D., & Butler, P. C.
- Affiliations
- University of California, Los Angeles (US)
- Mayo Clinic (US)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2006-03-01
- Volume
- 29
- Issue
- 3
- Pages
- 717-718
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2153777416
- Cited by
- 197
- References
- 16
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 5 · 2021: 12 · 2020: 8 · 2019: 3 · 2018: 8 · 2017: 7 · 2016: 10 · 2015: 18 · 2014: 12 · 2013: 11 · 2012: 15
- FWCI
- 17.28
- Type
- journal article
- Language
- en
- Open access
- green
- escholarship.org
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Larry L. Hillblom Foundation
- Deutsche Forschungsgemeinschaft
- National Institutes of Health
- National Institute of Diabetes and Digestive and Kidney Diseases (DK59579, R01DK061539, DK 29953, DK 61539, R01DK059579)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pancreatic function and diabetes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- beta-cell mass, fasting blood glucose, insulin secretion, glucose homeostasis, beta-cell function
- MeSH terms
- Aged, Aged, 80 and over, Autopsy, Blood Glucose, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Fasting, Humans, Middle Aged, Retrospective Studies, Cell Size, Insulin-Secreting Cells
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