Cited by 5Systemic Sclerosis and Related DiseasesConnective tissue disorders researchDermatologic Treatments and Research

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Clinical and Histological Characteristics of Localized Morphea, Generalized Morphea and Systemic Sclerosis: A Comparative Study Aided by Machine Learning

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Choi, Sooyeon, Kim, Jemin, Lee, Joo Hee, Lee, Yun Na, Lee, Ju Hee·2023·Acta Dermato-Venereologica

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  • A random forest model distinguished 181 patients with localized morphea, generalized morphea, and systemic sclerosis, with top differentiating features including anticentromere autoantibodies, anti-scl-70 autoantibodies, rheumatoid factor, histologic sclerosis, and noncutaneous manifestations.

    “Choi et al (2023) trained a random forest model, distinguishing 181 patients with localized morphea, generalized morphea, and systemic sclerosis (SSc), with top differentiating features (through SHAP) including anticentromere autoantibodies, anti—scl-70 autoantibodies, rheumatoid factor, histologic sclerosis, and noncutaneous manifestations.”

    From Artificial intelligence–enabled precision medicine for inflammatory skin diseases (2026) · cites this paper as Choi et al, 2023

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References 14 · Cited by 5

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  23. Succaria F, Kurban M, Kibbi AG, Abbas O. Clinicopathological study of 81 cases of localized and systemic scleroderma. J Eur Acad Dermatol Venereol 2013; 27: e191-196. · DOI
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Metadata

Authors
Choi, S., Kim, J., Lee, J. H., Lee, Y. N., & Lee, J. H.
Affiliations
Yonsei University (KR)
Corresponding author
Lee, Ju Hee
Venue
Acta Dermato-Venereologica
Published
2023-09-20
Volume
103
Pages
adv11953
ISSN
  • 0001-5555 (ISSN-L)
  • 1651-2057
OpenAlex
W4386889347
Cited by
5
References
14
Citations by year
2026: 1 · 2025: 2 · 2024: 2
FWCI
1.00
Type
journal article
Language
en
Open access
Locations
  • Acta Dermato Venereologica (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Korea Medical Device Development Fund
  • Ministry of Trade, Industry and Energy
  • Ministry of Food and Drug Safety
  • Ministry of Science and ICT, South Korea
Topics
  • Health Sciences › Medicine › Rheumatology › Systemic Sclerosis and Related Diseases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
Keywords
generalized morphea, systemic sclerosis, clinical features, histological characteristics, machine learning classification, differential diagnosis
MeSH terms
Machine Learning, Humans, Scleroderma, Localized, Scleroderma, Systemic

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