Region-specific Dissociation of Neuronal Loss and Neurofibrillary Pathology in a Mouse Model of Tauopathy

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Items 301–400 of 402

1. Deposition of Phosphorylated α-Synuclein in the rTg4510 Mouse Model of Tauopathy
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2. Tau Oligomers as Pathogenic Seeds: Preparation, Characterization, and Propagation In Vitro and In Vivo
   Urmi Sengupta, Rakez Kayed · 2024 · Methods in molecular biology
3. Intensive protein synthesis in neurons and phosphorylation of beta-amyloid precursor protein and tau-protein are triggering factors of neuronal amyloidosis and Alzheimer's disease
   Alexander V. Maltsev, Nikita V. Dovidchenko, Victor Konstantinovich Uteshev, Viktoriya V. Sokolik, O. M. Shtang, M. A. Yakushin, N. M. Sokolova, Alexey K. Surin, Oxana V. Galzitskaya · 2013 · Biomeditsinskaya Khimiya
4. Differential accumulation of tau pathology between reciprocal F1 hybrids of rTg4510 mice
   Yanagisawa, Daijiro, Hamezah, Hamizah Shahirah, Pahrudin Arrozi, Aslina, Tooyama, Ikuo · 2021 · Scientific Reports
5. Secondary RNA structure and nucleotide specificity contribute to internal initiation mediated by the human tau 5′ leader
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6. Animal Models of Acquired Epilepsy and Tauopathies
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8. The Biology and Pathobiology of Tau Protein
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9. Disrupted visual cortical plasticity in early neurodegeneration
   Amalia Papanikolaou, Fábio Ribeiro Rodrigues, Joanna Holeniewska, Keith Geoffrey Phillips, Aman B. Saleem, Samuel G. Solomon · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
10. Anticholinesterase and Antioxidant Activities of Spilanthes filicaulis Whole Plant Extracts for the Management of Alzheimer’s Disease
    Taiwo Olayemi Elufioye, Cynthia C. Unachukwu, Adebola Omowunmi Oyedeji · 2019 · Current Enzyme Inhibition
11. Genetics of Frontotemporal Dementia
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12. Tau and neurodegenerative disorders
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13. Frontotemporal dementia
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14. Amyloid precursor protein and tau transgenic models of Alzheimer‘s disease: insights from the past and directions for the future
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15. GLP-1 receptor agonist semaglutide ameliorates motor deficits and tau pathology in the rTg4510s mouse model
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16. Tau oligomers modulate synapse fate by eliciting progressive bipartite synapse dysregulation and synapse loss
    Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe, Yani Y. Ngwala, Doyle Lokitiyakul, Ivy Wong, Aaryan Vira, Yaofu Liu, Jackson H. Chen, Mahima Sharma et al. · 2026 · Molecular Neurodegeneration
17. Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic
    Christopher Janus, Carolina Hernandez, Victoria deLelys, Hanno M. Roder, Hans Welzl · 2016 · Methods in molecular biology
18. Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model
    Aleksandra Parka, Christiane Volbracht, Benjamin J. Hall, Jesper F. Bastlund, Maiken Nedergaard, Bettina Laursen, Paolo Botta, Florence Sotty · 2023 · Journal of Alzheimer s Disease
19. Pathology and pathophysiology
    Bradford Clark Dickerson · 2015 · Cambridge University Press eBooks
20. Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model
    Aleksandra Parka, Caroline Degel, Jakob Kisbye Dreyer, Ulrike Richter, Benjamin J. Hall, Jesper F. Bastlund, Bettina Laursen, Maiken Nedergaard, Florence Sotty, Paolo Botta · 2023 · Neurobiology of Disease
21. The Potential of Small Molecules in Preventing Tau Oligomer Formation and Toxicity
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22. Molecular Aspects of Memory Dysfunction in Alzheimer’s Disease
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23. Cytoplasmic aggregation of TDP43 and topographic correlation with tau and α-synuclein accumulation in the rTg4510 mouse model of tauopathy
    Yutaro Nakayama, James Kenn CHAMBERS, Yuta Takaichi, Kazuyuki Uchida · 2024 · Journal of Neuropathology & Experimental Neurology
24. Perinatal Suppression of Tau P301L Has a Long Lasting Preventive Effect against Neurodegeneration
    David Caouette, Zhiyong Xie, Anthony J. Milici, Max Kuhn, Thomas M A Bocan, Dewen Yang · 2013 · International Journal of Neuropathology
25. Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice
    Marangelie Criado‐Marrero, Danielle M. Blazier, Lauren A. Gould, Niat T. Gebru, Santiago Rodriguez Ospina, Debra S. Armendariz, April L. Darling, David Beaulieu‐Abdelahad, Laura J. Blair · 2022 · Scientific Reports
26. EFhd2 co-aggregates with monomeric and filamentous tau in vitro
    Ahlam S. Soliman, Andrew Umstead, Jared A. Lamp, Irving E. Vega · 2024 · Frontiers in Neuroscience
27. The Natural History of Alzheimer Disease Dissected Through Multiphoton Imaging of Transgenic Mice
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28. Toxic Tau Aggregation in AD
    Akihiko Takashima · 2014 · Advances in experimental medicine and biology
29. An automatic method for spine detection and spine tracking in in vivo images
    Jing Fan, Xiaobo Zhou, Jennifer Dy, Yong Zhang, Tara L. Spires‐Jones, Bradley T. Hyman, Stephen T. C. Wong · 2007 · IEEE/NIH Life Science Systems and Applications Workshop
30. Moderate Overexpression of Tau in Drosophila Exacerbates Amyloid-β-Induced Neuronal Phenotypes and Correlates with Tau Oligomerization
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31. Natural antioxidants in prevention and management of Alzheimer's disease
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32. The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic–ischemic near-term lamb
    Melinda Barkhuizen, Fleur J P van Dijck, Reint K. Jellema, Ruth Gussenhoven, Imke Engelbertink, Ralph J. S. van Mechelen, Jack P.M. Cleutjens, Matthias Seehase, Harry W.M. Steinbusch, Luc J. I. Zimmermann et al. · 2018 · Pediatric Research
33. Transgenic Animal Models of Proteinopathies
    Naruhiko Sahara, Heather L. Melrose, Simon D’Alton, Jada M. Lewis · 2011
34. Reducing Tau Ameliorates Behavioural and Transcriptional Deficits in a Novel Model of Alzheimer's Disease
    Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly M. Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Louise Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad et al. · 2018 · SSRN Electronic Journal
35. Targeting the Hsp90/Aha1 Complex for the Treatment of Tauopathies
    Lindsey B. Shelton · 2018 · Digital Commons - University of South Florida (University of South Florida)
36. Mitochondrial bioenergetics stimulates autophagy for pathological tau clearance in tauopathy neurons
    Nuo Jia, Dhasarathan Ganesan, Hongyuan Guan, Yu Young Jeong, Sinsuk Han, Marialaina Nissenbaum, Alexander W. Kusnecov, Qian Cai · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
37. A variant of the autophagic receptor NDP52 counteracts phospho-TAU accumulation and emerges as a protective factor for Alzheimer Disease
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38. Tau Oligomers in Alzheimer’s Disease: Modulation Effect of Osmolytes on Amplified Brain-Derived Tau Oligomers
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39. Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices
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40. Tau Oligomers as Potential Drug Target for Alzheimer Disease (AD) Treatment
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41. Molecular Mechanisms of Synaptic Plasticity and Memory and Their Dysfunction in Alzheimer's Disease ☆
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42. Traumatic Brain Injury Alters the Trajectory of Age-Related Mitochondrial Change
    Janna L. Harris, Xiaowan Wang, Sarah K. Christian, Lesya Novikova, Anuradha Kalani, Dongwei Hui, Sadie L. Ferren, Scott Barbay, Judit Perez Ortiz, Randolph J. Nudo et al. · 2024 · Journal of Alzheimer s Disease
43. Current and Future Therapies for Alzheimer Disease
    Paramita Chakrabarty, Pritam Das, Todd Eliot Golde · 2010 · Wiley eBooks
44. Evaluating the Therapeutic Effect of an Hsp90 Inhibitor in Mouse Models of Alzheimer’s Disease
    Bin Wang · 2016
45. Entrada de calcio inducida por los oligómeros del péptido amiloide en la Enfermedad de Alzheimer
    Erica Caballero Ortega · 2013
46. Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathy
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47. Age-associated increases in FKBP51 facilitate tau neurotoxicity
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48. Diet-Induced Ketosis and Calorie Restriction in Mouse Models of Alzheimer's Pathology
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49. Pseudophosphorylation of tau modulates its function and induces AD-like changes
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50. Mouse and stem cell models of frontotemporal dementia
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51. Multifaktorielle Genese des Synapsenuntergangs beim Morbus Alzheimer: Eine in vivo 2-Photonen Untersuchung an APP-Knockout und transgenen Alzheimer- Mausmodellen
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52. HISTOLOGICAL AND BEHAVIORAL CONSEQUENCES OF REPEATED MILD TRAUMATIC BRAIN INJURY IN MICE
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53. Pathophysiologyand animal models of frontotemporal dementia
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54. Tauopathy Mouse Models
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55. Attenuation of Spatial Memory Impairment in a Tau Mouse Model of Alzheimer's Disease with Riluzole
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56. Approach for Alzheimer's Disease
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58. Histological Evidence Of The Effect Of Oil Palm Phenolics In Atherogenic Diet Induced Rat Model Of Alzheimer’s Disease
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60. ERP-based Detection of Brain Pathology in Rat Models for Preclinical Alzheimer's Disease
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61. Engineering antibody therapeutics and cell culture models for neurodegenerative diseases
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62. THE ROLE OF HSF1 PROTEIN REGULATION ON NEURODEGENERATION
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64. Pathological Tau as a Cause, and Consequence, of Cellular Dysfunction
    Shelby E. Meier · 2019 · UKnowledge (University of Kentucky)
65. Modeling of Alzheimer’s Disease and Outlooks for its Therapy Using Induced Pluripotent Stem Cells
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66. Repetitive Mild Traumatic Brain Injury Increases APP and Phospho Tau within the Hippocampus of a Novel APP/Tau Mouse Model of Alzheimer’s Disease
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67. Quantitative analysis of the focused ultrasound-induced blood-brain barrier opening with applications in neurodegenerative disorders
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68. Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases
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69. Modulation of neuronal function by tau, alpha synuclein or carbon dioxide
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70. Faculty Opinions recommendation of Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue.
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71. Intensive protein synthesis in neurons and phosphorylation of beta-amyloid precursor protein and tau-protein are triggering factors of neuronal amyloidosis and Alzheimer’s disease
    Alexander V. Maltsev, Nikita V. Dovidchenko, Victor Konstantinovich Uteshev, Viktoriya V. Sokolik, O. M. Shtang, M. A. Yakushin, N. M. Sokolova, Alexey K. Surin, Oxana V. Galzitskaya · 2013 · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry
72. Mitochondrial complex I as a diagnostic and therapeutic target in a mouse model of tauopathy
    Jia Hui Wong, Anselm Salvatore Vincent, Shivashankar Khanapur, Tang Jun Rong, Boominathan Ramasamy, Siddesh V. Hartimath, Peter K.C. Cheng, Hideo Tsukada, Edward George Robins, Julian Goggi et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
73. Tau Transgenic Mouse Models in Therapeutic Development
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74. Creation of single App knock-in mouse models and of single MAPT knock-in models: Demonstration of Aβ-tau axis
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75. Alzheimer’s Disease
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76. Intracellular Trafficking SNARE Protein, Syntaxin-6, is a Modifier of Prion and Tau Pathogenesis in vivo and in Cellular Models
    Elizabeth Hill, Mitali Patel, Juan Manuel Ribes, Jacqueline M. Linehan, Fuquan Zhang, Michael Farmer, Tatiana Jakubcova, Shyma Hamdan, Andrew Tomlinson, Tiziana Ercolani et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
77. Soluble tau aggregates decrease the threshold for thalamic oscillations and increase the excitability of thalamic neurons
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79. Additional file 2 of Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy
    Haihan Jiao, Downie, Laura E., Xin Huang, Wu, Mengliang, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson, Holly Rose Chinnery · 2020 · Figshare
80. Additional file 1 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
    Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
81. Additional file 1 of Tau reduction in aged mice does not impact Microangiopathy
    Rachel E. Bennett, Miwei Hu, Analiese R. Fernandes, Perez-Rando, Marta, Robbins, Ashley, Tarun V. Kamath, Simon Dujardin, Bradley T. Hyman · 2020 · Figshare
82. Additional file 3 of Common mouse models of tauopathy reflect early but not late human disease
    Kathrin Wenger, Arthur Viodé, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony W. Bannon, Chang, Rui, Connors, Theresa R. et al. · 2023 · Figshare
83. Additional file 2 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
    Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
84. Additional file 6 of Common mouse models of tauopathy reflect early but not late human disease
    Kathrin Wenger, Arthur Viodé, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony W. Bannon, Chang, Rui, Connors, Theresa R. et al. · 2023 · Figshare
85. Additional file 4 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
    Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
86. Additional file 3 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
    Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
87. Additional file 1 of Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy
    Haihan Jiao, Downie, Laura E., Xin Huang, Wu, Mengliang, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson, Holly Rose Chinnery · 2020 · Figshare
88. Additional file 1 of Common mouse models of tauopathy reflect early but not late human disease
    Kathrin Wenger, Arthur Viodé, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony W. Bannon, Chang, Rui, Connors, Theresa R. et al. · 2023 · Figshare
89. Additional file 2 of Common mouse models of tauopathy reflect early but not late human disease
    Kathrin Wenger, Arthur Viodé, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony W. Bannon, Chang, Rui, Connors, Theresa R. et al. · 2023 · Figshare
90. Additional file 5 of Common mouse models of tauopathy reflect early but not late human disease
    Kathrin Wenger, Arthur Viodé, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony W. Bannon, Chang, Rui, Connors, Theresa R. et al. · 2023 · Figshare
91. Additional file 4 of Common mouse models of tauopathy reflect early but not late human disease
    Kathrin Wenger, Arthur Viodé, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony W. Bannon, Chang, Rui, Connors, Theresa R. et al. · 2023 · Figshare
92. Implications de la protéine DYRK1A dans la pathologie Alzheimer et développement de stratégies thérapeutiques
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93. Neurotoxicité précoce et mécanismes de neuroprotection dans des modèles poisson‐zèbre de tauopathies
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97. Differential accumulation of tau pathology between reciprocal F1 hybrids of rTg4510 mice.
    大治郎 柳沢, 育夫 遠山, Daijiro Yanagisawa, Hamizah Shahirah Binti HAMEZAH, Aslina Pahrudin Arrozi, Ikuo Tooyama · Institutional Repositories DataBase (IRDB)
98. Neurotoxic Tau Oligomers: Isolation, Preparation, and Characterization
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99. Investigating the role of EFhd2 protein in modulating tau pathology in a tauopathy mouse model
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