Evidence of Placental Translation Inhibition and Endoplasmic Reticulum Stress in the Etiology of Human Intrauterine Growth Restriction
Yung, Hong-wa, Calabrese, Stefania, Hynx, Debby, Hemmings, Brian A., Cetin, Irene, Charnock-Jones, D. Stephen, Burton, Graham J.·2008·The American Journal of Pathology
Cited by (388)
Items 301–388 of 388
- Maternal and Fetal PI3K-p110α Deficiency Induces Sex-Specific Changes in Conceptus Growth and Placental Mitochondrial Bioenergetic Reserve in MiceDaniela Pereira‐Carvalho, Esteban Salazar‐Petres, Jorge López‐Tello, Amanda Nancy Sferruzzi-Perri · 2022 · Veterinary Sciences
- Cyclin G2 Is Involved in the Proliferation of Placental Trophoblast Cells and Their Interactions with Endothelial CellsManni Sun, Shenghuan Liu, Jinlan Gao, Tao Meng, Xuesha Xing, Chen Chen, Haiying Chen, Yang Luo · 2020 · Medical Science Monitor
- No evidence of the unfolded protein response in the placenta of two rodent models of preeclampsia and intrauterine growth restrictionBarbara Denkl, Nada Cordasic, Hanna Huebner, Carlos Menendez‐Castro, Marius Schmidt, Alexander Mocker, Joachim Woelfle, Andrea Hartner, Fabian B. Fahlbusch · 2021 · Biology of Reproduction
- Placental structure, function and mitochondrial phenotype relate to fetal size and sex in miceEsteban Salazar‐Petres, Daniela Pereira Carvalho, Jorge López‐Tello, Amanda Nancy Sferruzzi-Perri · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal developmentTian Yue, Yongbo Guo, Xuebin Qi, Wangshan Zheng, Hui Zhang, Bin Wang, Kai Liu, Bin Zhou, Xuerui Zeng, Ouzhuluobu et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal developmentTian Yue, Yongbo Guo, Xuebin Qi, Wangshan Zheng, Hui Zhang, Bin Wang, Kai Liu, Bin Zhou, Xuerui Zeng, Ouzhuluobu et al. · 2023 · eLife
- CRISPR/Cas9-mediated SLC2A1 gene knockout changes in energy metabolism and cellular behavior in human trophoblastsHahyun Park, Seung-Min Bae, Taeyeon Hong, Gwonhwa Song, Whasun Lim · 2026 · Reproduction
- Role of Cellular Senescence in IUGR: Impact on Fetal Morbidity and DevelopmentAliabbas Zia, Faezeh Sahebdel, Yosra Er‐Reguyeg, Michel Desjarlais, Jean-Clément Mars, Gregory Anton Lodygensky, Sylvain Chemtob · 2025 · Cells
- Basic Structure of a Placental VillusGraham J. Burton · 2021 · Springer eBooks
- Lentivirus-Mediated Trophoblast-Specific Deptor Knockdown Increases Transplacental System A and System L Amino Acid Transport and Fetal Growth in MiceAvery C. Kramer, Owen R. Vaughan, Kenneth Barentsen, Johann Urschitz, Theresa L. Powell, Thomas Jansson, Fredrick Joseph Rosario · 2025 · Function
- Placental Protein Citrullination Signatures Are Modified in Early- and Late-Onset Fetal Growth RestrictionOwen R. Vaughan, Kasia Maksym, Sara L. Hillman, Rebecca N. Spencer, Mariya Hristova, Anna Louise David, Sigrun Lange · 2025 · International Journal of Molecular Sciences
- The hypoxic fetus as a patient: adaptations to the intrauterine environmentIrene Cetin, Isabella Abati · 2025 · Philosophical Transactions of the Royal Society B Biological Sciences
- Placental Function in Intrauterine Growth RestrictionYi‐Yung Chen, Thomas Jansson · 2016 · Elsevier eBooks
- The Placental CirculationsDavid S. Jones, Eric R. M. Jauniaux, Graham J. Burton · 2021 · Springer eBooks
- Use of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of PreeclampsiaWanying Dai, Angela Pollinzi, Micheline Piquette‐Miller · 2023 · Drug Metabolism and Disposition
- Increase in the number of patients diagnosed using the new classification of hypertensive disorders of pregnancy in JapanMichinori Mayama, Mamoru Morikawa, Takeshi Umazume, Kinuko Nakagawa, Ami Hosokawa, Masahiro Yamaguchi, Kentaro Chiba, Satoshi Kawaguchi, Hidemichi Watari · 2019 · Journal of obstetrics and gynaecology research
- Intrauterine growth restrictionJohn C. Kingdom, Melissa G. Walker, Sascha Drewlo, Sarah J. Keating · 2012 · Cambridge University Press eBooks
- Expression of the IGF‑1Ea isoform in human placentas from third trimester normal and idiopathic intrauterine growth restriction singleton pregnancies: Correlations with clinical and histopathological parametersApostolos Fasoulopoulos, Michail N. Varras, Fani‐Niki Varra, Αnastassios Philippou, Despoina Myoteri, Viktoria‐Konstantina Varra, Evgenia Kouroglou, Alexandros Gryparis, Αrgyro Papadopetraki, Iakovos Vlachos et al. · 2025 · Molecular Medicine Reports
- Trophoblast‐specific Deptor knockdown enhances trophoblast nutrient transport and fetal growth in miceLance G. A. Nunes, Rodrigo Barbano Weingrill, Sam Blessen J. Fredrick, Ramón A. Lorca, Men‐Jean Lee, Shaikh Muhammad Atif, Adam J. Chicco, Fredrick Joseph Rosario, Johann Urschitz · 2025 · Acta Physiologica
- PiggyBac transposase-mediated inducible trophoblast-specific knockdown of Mtor decreases placental nutrient transport and fetal growthFredrick Joseph Rosario, Johann Urschitz, Haide Razavy, Marlee Elston, Theresa L. Powell, Thomas Jansson · 2025 · Clinical Science
- The uteroplacental circulation at high altitude: adaptation and maladaptationXiang‐Qun Hu, Chiranjib Dasgupta, Yu Gao, Isaac Kremsky, Eugenia Mata‐Greenwood, Li Zhang · 2025 · Philosophical Transactions of the Royal Society B Biological Sciences
- Alpha‐enolase 1 knockdown facilitates the proliferation and invasion of villous trophoblasts by upregulating COX ‐2Huaiyun Tang, Linqing Pan, Lisha Tang, Jiayin Liu · 2023 · Molecular Genetics & Genomic Medicine
- The Paraoxonase 1 Arylesterase Activity, Total Oxidative Stress, Nitric Oxide and Vitamin C Levels in Maternal Serum, and Their Relation to Birth Weight of NewbornMukund Ramchandra Mogarekar, Mahendra G. Dhabe, Chanchal C. Gujrathi · 2015 · The Journal of Obstetrics and Gynecology of India
- sFlt-1 (sVEGFR1) induces placental endoplasmic reticulum stress in trophoblast cell: implications for the complications in preeclampsia- an in vitro studySankat Mochan, Manoj Kumar Dhingra, Betsy Varghese, Sunil Gupta, Shobhit A. Saxena, Pallavi Arora, Neerja Rani, Arundhati Sharma, Kalpana Luthra, Sadanand N. Dwivedi et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal developmentTian Yue, Yongbo Guo, Xuebin Qi, Wangshan Zheng, Hui Zhang, Bin Wang, Kai Liu, Bin Zhou, Xuerui Zeng, Ouzhuluobu et al. · 2024 · eLife
- Novel role for PI3Kβ in placental function through regulation of system A amino acid transporter expression, associated with embryonic lethalitySarah E. Conduit, Cindy X. W. Zhang, Wayne P Pearce, Julie Guillermet‐Guibert, Amanda Nancy Sferruzzi-Perri, Bart Vanhaesebroeck · 2025 · Cellular and Molecular Life Sciences
- Metabolic imprinting in trophoblast barrier dysfunction: the role of glucolipotoxicity, endoplasmic reticulum stress, and amino acid transport imbalanceShuo Zhang, Zi Xuan Shen, Pin Cao, Sha Ni, Dan Wang · 2026 · Journal of Assisted Reproduction and Genetics
- Intrauterine growth restriction inhibits expression of eukaryotic elongation factor 2 kinase, a regulator of protein translationRobert A. McKnight, Christian C. Yost, Erin K. Zinkhan, Qi Fu, Christopher W. Callaway, Camille M. Fung · 2016 · Physiological Genomics
- Parallel Mechanisms between Placental Amyloidosis/Preeclampsia and Neurodegenerative DiseasesCleofina Bosco, Erik Díaz-Bautista · 2017 · Asian Journal of Biology
- Effect of levetiracetam on the gene expression of placental transporters in a murine modelRicardo Blanco‐Castañeda, Yessica Zapata‐Vázquez, Blanca Patricia Lazalde-Ramos, Daniel Enríquez‐Mendiola, Ismael Lares‐Asseff, Carlos Galavíz-Hernández, Gerardo Martínez, Martha Sosa‐Macías · 2022 · Epilepsia
- Placental Anatomy and PhysiologyGraham J. Burton, Colin Peter Sibley, Eric R. M. Jauniaux · 2017 · Elsevier eBooks
- Gene and Protein Expression of Placental Nutrient-Stress Sensor Proteins in Fetal Growth RestrictionElizabeth Morgan, Grace Chung, Seokwon Jo, Briana Clifton, Sarah A. Wernimont, Emilyn U. Alejandro · 2024 · Stresses
- Different regulation of IRE1α and eIF2α pathways by oxygen and insulin in ACH-3P trophoblast modelVeronika Tandl, Denise Hoch, Julia Bandres‐Meriz, Sanela Nikodijevic, Gernot Desoyé, Alejandro Majali‐Martinez · 2021 · Reproduction
- Villous MaldevelopmentKurt Benirschke, Graham J. Burton, Rebecca N. Baergen · 2012 · Springer eBooks
- PiggyBac Transposase Mediated Inducible Trophoblast-specific Knockdown of Mechanistic Target of Rapamycin in Mice Decreases Placental Nutrient Transport and Inhibits Fetal GrowthFredrick Joseph Rosario, Johann Urschitz, Haide Razavy, Marlee Elston, Theresa L. Powell, Thomas Jansson · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal developmentTian Yue, Yongbo Guo, Xuebin Qi, Wangshan Zheng, Hui Zhang, Bin Wang, Kai Liu, Bin Zhou, Xuerui Zeng, Ouzhuluobu et al. · 2024 · eLife
- Mechanistic target of rapamycin signaling activity in the human placenta across gestation and in maternal obesityKatie L Bidne, Kathryn Erickson, Theresa L. Powell, Thomas Jansson · 2025 · Biology of Reproduction
- Is Preeclampsia a Protein Misfolding and Aggregation Disease?Shi Bin Cheng · 2014 · Journal of Tropical Diseases
- Diffuse decidual leucocytoclastic necrosis and NK cell aggregates: two distinct features of miscarriageJoong Yeup Lee, Eun Na Kim, Joon‐Seok Hong, Jae‐Yoon Shim, Doyeong Hwang, Ki Chul Kim, Jung-Bok Lee, Chong Jai Kim · 2014 · Journal of Clinical Pathology
- Hematological and Biochemical Findings in Fetal Growth Restriction and Relationship to HypoxiaIrene Cetin, Chiara Mandò · 2018 · Cambridge University Press eBooks
- Fetal Growth Restriction: Placental Basis and Implications for Clinical PracticeJohn C. Kingdom, Melissa G. Walker, Sascha Drewlo, Sarah J. Keating · 2019 · Cambridge University Press eBooks
- Some Aspects of the Physiology of the PlacentaLawrence D. Longo · 2018 · Springer eBooks
- Heterogeneity of mesenchymal cells in human amniotic membrane at term.S Cortés Sandoval, Vicente Seco‐Rovira, Ester Beltrán‐Frutos, María Isabel Serrano-Sánchez, Jesús Martínez‐Hernández, Concepción Ferrer, Juan Luis Delgado⋈, Carmen L. Insausti, Miguel Blanquer, Luis Miguel Pastor · 2024 · PubMed
- Sleep duration, napping behaviors and restless legs syndrome during pregnancy and the trajectories of ultrasonographic measures of fetal growth: Findings from the NICHD Fetal Growth Studies–SingletonsMuzi Na, Samidha Shetty, Xiaoyue Maggie Niu, Stefanie N. Hinkle, Cuilin Zhang, Xiang Gao · 2024 · Sleep Health
- Krüppel-like factor 6 involvement in the endoplasmic reticulum homeostasis of extravillous trophoblastsLucille Tihomirova Kourdova, Andrea Lis Miranda, Milagros Ovejero, Agustín Anastasía, Susana Genti‐Raimondi, Ana Cristina Racca, Graciela María Panzetta-Dutari · 2024 · Placenta
- Altered expression of AKT1 and P38A in the colons of patients with Hirschsprung’s diseaseLihua Wu, Ping Xiao, Qi Li, Zhen Zhang, Hui Wang, Qian Jiang, Long Li · 2020 · Pediatric Surgery International
- Characterization of the nicotine-induced endoplasmic reticulum stress response in the rat placenta in vivo and in vitroMichael K. Wong · 2015 · Scholarship@Western (Western University)
- The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human PlacentaSara Roos · 2008 · Gothenburg University Publications Electronic Archive (Gothenburg University)
- The effect of lifelong maternal obesity on pregnancy outcomes and placental developmentEmily K. Hayes · 2012 · MacSphere (McMaster University)
- Investigating the role of ion channels across the fetomaternal interface of the human placentaTayyba Ali · 2012 · Nottingham ePrints (University of Nottingham)
- Oxidative Stress in PathogenesisMohinder Bansal, Naveen Kaushal · 2014 · Springer eBooks
- Positive contribution of IRE1α–XBP1 pathway to the expression of placental cathepsinsDaisuke Oikawa, Takao Iwawaki · 2013 · Biochemical and Biophysical Research Communications
- A Comparative Pathophysiological Study of Normal and Growth Retarded Human Placental TissueAdam Moyosore Afodun, Khadijah Kofoworola Quadri, Mustapha Akajewole Masud, Oluseyi Abimbola Ogunsola, Abdurrasheed Ola Muhammad, Rafiu Abioye Ajiboye, Eziekel Ademola Caxton-Martins · 2014 · Physiology Journal
- Molecular Mechanisms Underlying the Early Life Programming of the LiverGurjeev Sohi · 2013 · Scholarship@Western (Western University)
- THE ROLE OF ABNORMAL MATERNAL INFLAMMATION IN THE PATHOGENESIS OF PREGNANCY COMPLICATIONSTiziana Cotechini · 2014 · QSpace (Queen's University Library)
- Insulin stimulation of Akt/PKB phosphorylation in the placenta of preeclampsia patients=Estimulação com insulina da fosforilação da Akt/PKB em placenta de pacientes com pré-eclâmpsiaGustavo Dias Ferreira, Rafael Bueno Orcy, Sérgio Hofmeister de Almeida Martins Costa, José Geraldo Lopes Ramos, Ilma Simoni Brum, Helena von Eye Corleta, Edison Capp · 2011 · Americanae (AECID Library)
- Some Aspects of the Physiology of the PlacentaLawrence D. Longo · 2013 · Springer eBooks
- The Role of PPAR-γ in Trophoblast Layer Dynamics Based on a Cell Model of Trophoblast DifferentiationKhrystyna Levytska · 2013 · TSpace (University of Toronto)
- Variations in Inflammatory and Cell Cycle Genes and Preterm Birth, Small for Gestational Age and Hypertensive Disorders of PregnancyQuaker E. Harmon · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
- Volumetric Blood Flow and Assessment of the Metabolic Profile of the Developing Brain in Growth Restricted Fetuses: An Ultrasound and Proton Magnetic Resonance Spectroscopy StudyLisa Story · 2011
- Trimester-specific Zika virus infection affects placental responses in womenFok‐Moon Lum, Vipin Narang, Susan Swee‐Shan Hue, Jie Chen, Naomi N. McGovern, Ravisankar Rajarethinam, Jeslin J. L. Tan, Siti Naqiah Amrun, Yi‐Hao Chan, Cheryl Yi‐Pin Lee et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- THE ROLE OF OXIDATIVE STRESS ON PERINATAL PATHOLOGYȘadiye-Ioana Scripcariu, Andreea Luciana Avasiloaiei, Maria Stamatin · 2019 · The Medical-Surgical Journal
- Embryonic heart rate correlates with maternal temperature and developmental stage in viviparous snakesKelly E. Evans, Lilly J. Brummett, Lucia L Combrink, Kaitlyn G. Holden, Giacomo Catalina, Sierra Farrar, Caleb Rodriguez, Amanda M. Sparkman · 2020 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
- Upregulation of ENDOU in cytotrophoblasts from placenta complicated with preeclampsia and fetal growth restrictionMasataka Nomoto, Tomomi Kotani, Rika Miki, Takafumi Ushida, Kenji Imai, Yukako Iitani, Sho Tano, Jingwen Wang, Yoshinori Moriyama, Tomoko Kobayashi et al. · 2021 · Journal of Clinical Biochemistry and Nutrition
- Characteristics of Fetal Growth RestrictionChristoph C. Lees, Gerard H.A. Visser, Kurt Hecher · 2018
- Environmental Pollution and Health ConsequencesPavel Rössner, Radim J. Šrám · 2014 · Oxidative stress in applied basic research and clinical practice
- Cellular Functions of ER Chaperones in Regulating Protein Misfolding and Aggregation: An Emerging Therapeutic Approach for PreeclampsiaJanaranjani Murugesan, Ajithkumar Balakrishnan, Kumpati Premkumar, Hemamalini Vedagiri · 2022 · IntechOpen eBooks
- Placentation and Placental Function in Normal and Preeclamptic PregnanciesGraham J. Burton, Tereza Cindrová‐Davies, Hong Wa Yung, Robert N. Taylor · 2022 · Elsevier eBooks
- Metals Mixtures Modeling Identifies Birth Weight-Associated Gene Networks in the Placentas of Children Born Extremely PretermLauren A. Eaves, Catherine M. Bulka, Julia E. Rager, Aubrey L. Galusha, Patrick J. Parsons, Thomas Michael O’Shea, Rebecca C. Fry · 2022 · SSRN Electronic Journal
- Efeito do soro de gestantes com pré-eclâmpsia sobre a via de estresse de retículo endoplasmático em células trofoblásticas.Karla Ribeiro de Castro · 2020 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal developmentTian Yue, Yongbo Guo, Xuebin Qi, Wangshan Zheng, Hui Zhang, Bin Wang, Kai Liu, Bin Zhou, Xuerui Zeng, Ouzhuluobu et al. · 2023 · eLife
- Pré-eclâmpsiaJosé Paulo de Siqueira Guida · 2021
- Avaliação dos efeitos da suplementação nutricional com leucina sobre a atividade placentárias de ratas portadoras de tumor de Walker 256 ao longo da prenhezCarla de Moraes Salgado · 2021
- Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal developmentTian Yue, Yongbo Guo, Xuebin Qi, Wangshan Zheng, Hui Zhang, Bin Wang, Kai Liu, Bin Zhou, Xuerui Zeng, Ouzhuluobu et al. · 2024 · eLife
- Interplay of stromal cell–derived factor 2 and endoplasmic reticulum stress in the placenta: A reviewEstela Maris Andrade Forell Bevilacqua, CRR Rocha, Hong Wa Yung, Graham J. Burton, Aline R. Lorenzon · 2025 · Placenta
- Parasympathetic and Sympathetic Nervous System Dysfunction and MonitoringNicholas L. DePace, Stephen Soloway, Michael F. Yayac, Joe Colombo · 2025 · Springer eBooks
- Inducible trophoblast-specific knockdown of mechanistic target of rapamycin impairs placental folate transport in miceHiroshi Shimada, Johann Urschitz, Theresa L. Powell, Thomas Jansson, Fredrick Joseph Rosario · 2025 · The Journal of Nutritional Biochemistry
- Additional file 1 of CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newbornsEmma Barroso, Marta Díaz, Reguera, Ana Cristina, Mona Peyman, Jesús Balsinde, Javier Jurado-Aguilar, Meijian Zhang, Adel Rostami, Xavier Palomer, Lourdes Ibáñez et al. · 2024 · Figshare
- Isolation Strategy Matters: How Tissue Processing Shapes the Composition of Placental Extracellular VesiclesParinaz Kazemi, Elaine Lee, Daniel Dufort · 2025 · Journal of Extracellular Biology
- The placenta at term: insights from the Loke Centre for Trophoblast Research 18th Annual Meeting, 2025Noa Hasky · 2026 · Biology Open
- Endoplasmic Reticulum Stress‐Induced Membrane Exposure of Calreticulin Serves as a Guide for Phagocytic Removal of Stressed‐But‐Viable CytotrophoblastsMidori Ikezaki, Kaho Nishioka, Kazuchika Nishitsuji, Megumi Fujino, Noa Mori, Kenji Uchimura, Kazuhiko Ino, Naoyuki Iwahashi, Yoshito Ihara · 2026 · Journal of obstetrics and gynaecology research
- Targeted Intracellular Delivery of Amino Acids to Trophoblast Cells Reveals Proteomic Signatures of Cellular UtilisationEmily Mazey, Sarah Flannery, Román Fischer, Neva Kandžija, Wei Zhang, Yuma Yamada, Manabu Tokeshi, Errin Johnson, Naveed Akbar, James M. Bancroft et al. · 2026 · Biomolecules
- RNF126 mediates fetal growth restriction via ubiquitination-dependent degradation of the MYH9/MYH10 complexLilin Lu, Xiaomei Ye, Jiawen Lan, Shuxiu Xu, Manyu Cheng, Chenlin Lv, Jun Zhou, Jing Li · 2026 · iScience
- Sexual Dimorphism in Placental mTORC1 Signaling, Amino Acid Transport, and Mitochondrial Respiration at TermHiroshi Shimada, Toshihide Sakuragi, Vincent Zaegel, Anita W. Kramer, Kristen E. Boyle, Theresa L. Powell, Thomas Jansson, Fredrick Joseph Rosario · 2026 · Antioxidants
- Maternal lifestyle risk factors and human embryonic morphologic development using 3D ultrasound: a population-based prospective cohort studyNaomi Graafland, Anke G. Posthumus, Annemarie G. M. G. J. Mulders, Romy Gaillard, Anton H. J. Koning, Vincent W. V. Jaddoe, Eric A.P. Steegers, Melek Rousian · 2026 · Human Reproduction
- The maternal–placental–fetal liver axis: A mechanistic framework for understanding benzene developmental hematotoxicityPerri M. Grant, Megan E Cull, Holly Mackay, Caitlyn I. Kirkpatrick, Louise M. Winn · 2026 · Reproductive Toxicology
- The role of p53 modulation in correcting aberrant placental apoptosis in pre-eclampsia and IUGRAndrew Sharp · 2011 · Research Explorer (The University of Manchester)
- Intergenerational effects of early life programming: The role of glucocorticoids and maternal obesityLincoln Liu · 2011 · ERA