Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease
Doi, Yukiko, Mizuno, Tetsuya, Maki, Yuki, Jin, Shijie, Mizoguchi, Hiroyuki, Ikeyama, Masayoshi, Doi, Minoru, Michikawa, Makoto +2 more·2009·The American Journal of Pathology
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- Embryonic Neocortical Microglia Express Toll-Like Receptor 9 and Respond to Plasmid DNA Injected into the Ventricle: Technical Considerations Regarding Microglial Distribution in Electroporated Brain WallsYuki Hattori, Takaki Miyata · 2018 · eNeuro
- Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of NeprilysinYukiko Doi, Hideyuki Takeuchi, Hiroyuki Mizoguchi, Kazuya Fukumoto, Hiroshi Horiuchi, Shijie Jin, Jun Kawanokuchi, Bijay Parajuli, Yoshifumi Sonobe, Tetsuya Mizuno et al. · 2014 · PLoS ONE
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- Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta ClearanceTarja Malm, Johanna M. Magga, Jari Koıstınaho · 2012 · Current Translational Geriatrics and Experimental Gerontology Reports
- Toll-Like Receptor Signaling in Alzheimer?s Disease ProgressionEric J. Downer · 2012 · Journal of Alzheimer’s Disease & Parkinsonism
- Oligomeric amyloid β facilitates microglial excitotoxicity by upregulating tumor necrosis factor‐α and downregulating excitatory amino acid transporter 2 in astrocytesHiroshi Horiuchi, Bijay Parajuli, Jun Kawanokuchi, Shijie Jin, Tetsuya Mizuno, Hideyuki Takeuchi, Akio Suzumura · 2015 · Clinical and Experimental Neuroimmunology
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- Capturing Amyloid-β Oligomers by Stirring with Microscaled Iron Oxide Stir Bars into Magnetic Plaques to Reduce Cytotoxicity toward Neuronal CellsYuan-Chung Tsai, Jing-Chian Luo, Te‐I Liu, I-Lin Lu, Ming‐Yin Shen, Chun‐Yu Chuang, Chorng‐Shyan Chern, Hsin‐Cheng Chiu · 2020 · Nanomaterials
- Toll‑Like receptor 4 promotes the phosphorylation of CRMP2 via the activation of Rho‑kinase in MCAO ratsXue‐Bo Li, Ming‐Xia Ding, Chun-Li Ding, Liang‐Liang Li, Jinzhou Feng, Xiaojun Yu · 2018 · Molecular Medicine Reports
- Innate Immunity Stimulation via Toll-Like Receptor 9 Ameliorates Vascular Amyloid Pathology in Tg-SwDI Mice with Associated Cognitive BenefitsHenrieta Scholtzova, Eileen Do, Shleshma Dhakal, Yanjie Sun, Shan Liu, Pankaj D Mehta, Thomas Wısnıewskı · 2017 · Journal of Neuroscience
- Innate Immune Mechanisms in the Central Nervous SystemAbhishek Shastri, Hadida Yasmin, Uday Kishore · 2025 · Advances in experimental medicine and biology
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- Mechanisms and Clinical Significance of Endosomal Toll-Like Receptors in Neurological DiseasesWeihua Kong, Xinglu Miao, Ruili Dang, Pei Jiang, Lei Feng · 2025 · Molecular Neurobiology
- New Insights into Microglia as Therapeutic Targets in Alzheimer’s DiseaseDeepa S. Mandlik, Satish K. Mandlik, Heena Bholaram Choudhary · 2023 · Current Drug Therapy
- The Role of Telomere Maintenance in Adult Mammalian Acute Central Nervous System Injury and Retinal Ganglion Cell ApoptosisMeghan D. Lysko · 2016 · TSpace (University of Toronto)
- Roles in Immune ResponsesRicha Hanamsagar, Sandra M. Cardona, Tammy Kielian, Astrid E. Cardona · 2014 · Springer eBooks
- Erratum to: Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta ClearanceTarja Malm, Johanna M. Magga, Jari Koıstınaho · 2012 · Current Translational Geriatrics and Experimental Gerontology Reports
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- ApoE-directed CpG nano-immunoadjuvant ameliorates Alzheimer's-like pathology in miceXin Huang, Yan-Yun Sun, Yi-Ren Qin, Hong Chen, Ting-Ting Pan, Songsong Zhao, Qian Cai, Xiaoshuo Zhang, Xiao-dong Nie, Lei Feng et al. · 2026 · Journal of Controlled Release
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- Preclinical gene therapy using recombinant AAV vectors in mouse models of two human diseasesYasemin Özgür Günes · 2022 · theses.fr (ABES)