PreprintCited by 6Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and ApplicationsMetabolomics and Mass Spectrometry Studies

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Fragment correlation mass spectrometry: determining the structures of biopolymers in a complex mixture without isolating individual components

Open access
Li, Yangjie, Cavet, Guy L, Zare, Richard N, Driver, Taran·2024·Proceedings of the National Academy of Sciences

Preprint — published as 10.1073/pnas.2409676121 · Paper page

Abstract

Fragment correlation mass spectrometry correlates ion pairs generated from the same fragmentation pathway, achieved by covariance mapping of tandem mass spectra generated with an unmodified linear ion trap without pre-separation. We enable identification of different precursors at different charge states in a complex mixture from a large isolation window, empowering a new analytical approach for data-independent acquisition. The method resolves and matches isobaric fragments, internal ions, and disulfide bond fragments.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.26434/chemrxiv-2024-pl3t1

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Metadata

Authors
Li, Y., Cavet, G. L., Zare, R. N., & Driver, T.
Affiliations
  • Stanford University (US)
  • Flatiron Bio, LLC
  • SLAC National Accelerator Laboratory (US)
Corresponding author
  • Zare, Richard N
  • Driver, Taran
Venue
Proceedings of the National Academy of Sciences
Published
2024-05-13
Volume
121
Issue
32
Pages
e2409676121-e2409676121
ISSN
0027-8424 (ISSN-L)
OpenAlex
W4401071082
Cited by
6
References
1
Citations by year
2026: 2 · 2025: 2 · 2024: 2
FWCI
0.75
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion, cc-by-nc-nd)
  • ChemRxiv (acceptedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
Air Force Office of Scientific Research (AFOSR FA9550-21-1-0170)
Topics
  • Physical Sciences › Chemistry › Spectroscopy › Mass Spectrometry Techniques and Applications
  • Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
Keywords
tandem mass spectrometry, covariance mapping, linear ion trap, data-independent acquisition, complex mixtures, precursor identification, charge states

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review