Parthanatos, a messenger of death
David, Karen Kate·2009·Frontiers in Bioscience
DOI 10.2741/3297
Cited by (451)
Items 301–400 of 451
- Impact of Parthanatos on the Increased Risk of Onset and Mortality in Male Patients With Pulmonary HypertensionZhen-Chun Lv, Fei Li, Lan Wang, Qin-Hua Zhao, Gong-Su Gang, Yue Wu, Yuqing Miao, Ping Yuan · 2021 · American Journal of Men s Health
- The Role of Regulatory Cell Death in VitiligoLyu-Ye Liu, Sijia He, Chen Zhao, Man Ge, Chunyi Lyu, Dandan Gao, Ji-Peng Yu, Menghan Cai, Jinxiang Yuan, Junling Zhang · 2023 · DNA and Cell Biology
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- Comprehensive analysis of regulated cell death pathways: intrinsic disorder, protein–protein interactions, and cross-pathway communicationOleksandr Sorokin, Frank Hause, Alice Wedler, Tala Alakhras, Theresa Bauchspiess, Anne Dietrich, Wiebke F. Günther, Coninika Guha, Kingsley Benjamin Obika, Joshua Kraft et al. · 2025 · APOPTOSIS
- iPCD: A Comprehensive Data Resource of Regulatory Proteins in Programmed Cell DeathDachao Tang, Cheng Han, Shaofeng Lin, Xiaodan Tan, Weizhi Zhang, Di Peng, Chenwei Wang, Yu Xue · 2022 · Cells
- 4′-O-methylbavachalcone alleviates ischemic stroke injury by inhibiting parthanatos and promoting SIRT3Hong-qing Chen, Q G Zhang, Xin-yuan Zhang, Xiang-bing Zeng, Jin‐Wen Xu, Shuang Ling · 2024 · European Journal of Pharmacology
- PARP-1 dependent cell death pathway (Parthanatos) mediates early brain injury after subarachnoid hemorrhageYuwei Han, Chenchen Wang, Xiaoming Li, Guobiao Liang · 2024 · European Journal of Pharmacology
- Apoptosis and AutophagyFrancesco Merolla · 2013 · Springer eBooks
- Ethanol-induced changes in poly (ADP ribose) polymerase and neuronal developmental gene expressionDavid P. Gavin, Handojo Kusumo, Rajiv P. Sharma, Marina Guizzetti · 2016 · Neuropharmacology
- The effects of nicotinamide on reinstatement to cocaine seeking in male and female Sprague Dawley ratsEmily A. Witt, Kathryn J. Reissner · 2019 · Psychopharmacology
- Evaluation of ABT-888 in the amelioration of α-synuclein fibril-induced neurodegenerationLyndsay Hastings, Arpine Sokratian, Daniel J. Apicco, Christina M. Stanhope, Lindsey Smith, Warren D. Hirst, Andrew B. West, Kaela Kelly · 2022 · Brain Communications
- Causes and consequences of DNA double-stranded breaks in cardiovascular diseaseAli J. Marian · 2024 · Molecular and Cellular Biochemistry
- Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophySaki Sakakura, Emi Inagaki, Tomoko Sayano, Risa Yamazaki, Noemi Fusaki, Shin Hatou, Masatoshi Hirayama, Kazuo Tsubota, Kazuno Negishi, Hideyuki Okano et al. · 2023 · Regenerative Therapy
- Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cellsFaiza Tahia, Sandip Kumar Basu, Amanda Prislovsky, Koushik Mondal, Dejian Ma, Harry Kochat, Kennard Brown, Daniel Stephenson, Charles Edward Chalfant, Nawajes A. Mandal · 2024 · Experimental Eye Research
- Parthanatos‐associated proteins are stimulated intraocularly during development of experimental murine cytomegalovirus retinitis in mice with retrovirus‐induced immunosuppressionJay J. Oh, Jessica J. Carter, J.G. Nemeno, Richard D. Dix · 2019 · Journal of Medical Virology
- Helicobacter pyloriactivation of PARP-1Carlos Wolfgang Nossa, Steven R. Blanke · 2010 · Gut Microbes
- The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cellsBenigno C. Valdez, Li Yang, David L. Murray, Yan Liu, Yago L. Nieto, Richard E. Champlin, Börje S. Andersson · 2017 · Leukemia & lymphoma/Leukemia and lymphoma
- Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying DiseasesJean‐Marie Ravel, Luis Cristóbal Monraz Gómez, Nicolas Sompairac, Laurence Calzone, Boris Zhivotovsky, Guido Kroemer, Emmanuel Barillot, Andrei Y. Zinovyev, Inna Kuperstein · 2020 · Cancers
- Alzheimer’s disease: a jigsaw puzzle comprised of different types of programmed cell death piecesYu Wang, Dan Mu, Ying Li, Chang Liu, Jianan Feng, Yong Lai, Guanhua Lou · 2025 · Brain Research
- Unraveling the intriguing interplay: Exploring the role of lncRNAs in caspase‐independent cell deathYusuf Cem Çiftçi, İpek Erdoğan, Bünyamin Akgül · 2024 · Wiley Interdisciplinary Reviews - RNA
- Ozone therapy mitigates parthanatos after ischemic strokeJiahui Li, Xiaolei Liu, Zengze Wang, Pengyun Xie, Min Zhu, Hanhui Zhong, Sirui Luo, Jing Yi Tang, Guixi Mo · 2024 · Biological Research
- Insight into the machinery that oils chromatin dynamicsRoni H. G. Wright, Narcís Fernández‐Fuentes, Baldomero Oliva, Miguel Beato · 2016 · Nucleus
- Etiology and pathogenesis of Parkinson diseaseJoseph J. Jankovic, Mark Hallett, Michael S. Okun, Cynthia Comella, Stanley Fahn, Jennifer G. Goldman · 2021 · Elsevier eBooks
- Chronic NOD2 stimulation by MDP confers protection against parthanatos through M2b macrophage polarization in RAW264.7 cellsFlorencia Celeste Mansilla, María Cruz Miraglia, Silvina Soledad Maidana, Cecilia P. Randazzo, Alejandra Victoria Capozzo · 2024 · Immunobiology
- Mono‐ADP‐Ribosylation of Peptides: An Overview of Synthetic and Chemoenzymatic MethodologiesHugo Minnee, Jeroen D. C. Codée, Dmitri V. Filippov · 2024 · ChemBioChem
- Inhibiting De Novo Biosynthesis of Ceramide by L-Cycloserine Can Prevent Light-Induced Retinal Degeneration in Albino BALB/c MiceFaiza Tahia, Dejian Ma, Daniel Stephenson, Sandip Kumar Basu, Nobel A. Del Mar, Nataliya I. Lenchik, Harry Kochat, Kennard Brown, Charles Edward Chalfant, Nawajes A. Mandal · 2024 · International Journal of Molecular Sciences
- Poly (ADP‐Ribose) Glycohydrolase‐Dependent dePARylation of PCNA Is Essential for DNA ReplicationZhenzhen Yan, Qianxi Feng, Xiuhuan Jiang, Xiaoru Han, Zichang Qiao, Yaguang Wang, Xiaoyun Yang, Xiuhua Liu, Xinying Cheng, Shuai Guo et al. · 2025 · The FASEB Journal
- Chaperone‐mediated autophagy attenuates H2O2‐induced cardiomyocyte apoptosis by targeting poly (ADP‐ribose) polymerase 1 (PARP1) for lysosomal degradationDandan Zhang, Lai Wei, Yang Liu, Rong Wan, Yang Shen · 2022 · Cell Biology International
- Recent Progress in Small-Molecule Inhibitors for Critical Therapeutic Targets of NecroptosisZhennan Fang, Huiqiang Wei, Wenfeng Gou, Leyuan Chen, Changfen Bi, Wenbin Hou, Yiliang Li · 2021 · Future Medicinal Chemistry
- Necrosis, Apoptosis, and Autophagy: Mechanisms of Neuronal and Glial Cell DeathMichael Fricker, Aviva M. Tolkovsky · 2011 · Neuromethods
- The role and regulation of cell death in cancerMinh Trong Quang, Minh Nam Nguyen, Van Thai Than · 2025 · Progress in molecular biology and translational science
- PARP enzyme synthesis of protein-free poly(ADP-ribose): Implications for DNA damage signaling and repairMarie-France Langelier, John M. Pascal · 2025 · DNA repair
- PARP inhibitors as radiosensitizers: a comprehensive review of preclinical evidence and clinical applicationsXiaodong Luo, Shuo Gao, Kaiyang Sun, Zhiqiang Dong, Shude Yang · 2025 · Frontiers in Oncology
- Unveiling the therapeutic potential of natural-based anticancer compounds inducing non-canonical cell death mechanismsEsra Bozgeyi̇k, İbrahim Bozgeyik · 2023 · Pathology - Research and Practice
- Creation of signatures and identification of molecular subtypes of glioblastoma based on disulfidptosis-related genes for predicting patient prognosis and immunological activityDongjun Li, Xiaodong Li, Jianfeng Lv, Shaoyi Li · 2024 · Asian Journal of Surgery
- CHD1L Regulates Cell Survival in Breast Cancer and Its Inhibition by OTI-611 Impedes the DNA Damage Response and Induces PARthanatosRita Sala, Hector Esquer, Timothy Kellett, Jeffrey T. Kearns, Paul Awolade, Qiong Zhou, Daniel V. LaBarbera · 2024 · International Journal of Molecular Sciences
- Karyoptosis as a novel type of UVB-induced regulated cell deathWeidong Chen, Jiin Byun, Han Chang Kang, Hye Suk Lee, Joo Young Lee, Young Jik Kwon, Yong‐Yeon Cho · 2024 · Free Radical Research
- Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivoHidemitsu Nakajima, Masanori Itakura, Keishi Sato, Sunao Nakamura, Yasu‐Taka Azuma, Tadayoshi Takeuchi · 2017 · Biochemical and Biophysical Research Communications
- Increased nucleotide metabolism alleviates Alzheimer’s disease pathologyYizhou Yu, Michael B. Miller, August Yue Huang, Bryan Wei Zhi Tan, Ivana Celardo, Nuno Santos Leal, Samantha H. Y. Loh, L. Miguel Martins · 2025 · Cell Death and Disease
- Programming regulated cell death to engineer whole-tumor-cell vaccines for cancer immunotherapyYingchao Guan, Die Bai, Na Bu, Wenhui Hao, Yasen Maimaitiyiming · 2026 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- CHD1L Inhibitor OTI-611 Synergizes with Chemotherapy to Enhance Antitumor Efficacy and Prolong Survival in Colorectal Cancer Mouse ModelsRita Sala, Hector Esquer, Timothy Kellett, Sophia Clune, Paul Awolade, L. Pike, Qiong Zhou, W. Messersmith, Daniel V. LaBarbera · 2024 · International Journal of Molecular Sciences
- Transient Global Cerebral Ischemia Produces Morphologically Necrotic, Not Apoptotic NeuronsF. Colbourne, R. Auer · 2010 · Springer eBooks
- Improved antitumor activity through a tyramidyl maslinic acid derivative. Design and validation as drug-loaded electrospun polymeric nanofibersCristina Luque, María de la Cabeza Fernández, David Fuentes‐Ríos, Ana Luisa Cepero, Rafael Contreras‐Cáceres, Manuel Doña, Gloria Perazzoli, Laura Lozano Chamizo, Marco Filice, Marzia Marciello et al. · 2023 · European Journal of Pharmaceutics and Biopharmaceutics
- The assessment of an in-vitro model for evaluating the role of PARP in ethanol-mediated hepatotoxicityRichard Harbison, JaymeP Coyle, Amora Mayo-PEREZ, M Bourgeois, G Johnson, S Morris · 2015 · International Journal of Critical Illness and Injury Science
- Poly (ADP-ribose) induces α-synuclein aggregation in neuronal-like cells and interacts with phosphorylated α-synuclein in post mortem PD samplesLaura N. Puentes, Zsofia Lengyel‐Zhand, Ji Youn Lee, Chia‐Ju Hsieh, Mark E. Schneider, Kimberly J. Edwards, Kelvin C. Luk, Virginia M.‐Y. Lee, John Q. Trojanowski, Robert H. Mach · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Host regulator PARP1 contributes to sex differences and immune responses in a mouse model of tuberculosisStefanie Krug, Alvaro A. Ordoñez, Mariah H. Klunk, Bong Gu Kang, Sanjay Kumar Jain, Ted M. Dawson, Valina Lynn Dawson, William R. Bishai · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potentialSophia Clune, Paul Awolade, Hector Esquer, Qiong Zhou, Daniel V. LaBarbera · 2025 · Journal of Experimental & Clinical Cancer Research
- Dysregulated Intracellular Signaling in the Pathogenesis of Vitiligo: An Update on Emerging Therapeutic StrategiesRamona Marrapodi, Alberto Marini, Barbara Bellei · 2025 · Biomedicines
- SARM1 executes neuronal parthanatos and promotes excitotoxic cell deathTong Wu, Liya Yuan, Yo Sasaki, Si Jia Chen, William Buchser, A. Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt · 2026 · Neuron
- Programmed cell death in lung cancer: mechanisms, immune responses, and therapeuticsYang Liu, Qingxin Chen, Jiayu Xu, Hao Chi · 2026 · APOPTOSIS
- Targeting PARP1-dependent parthanatos in Alzheimer's disease: Mechanisms and therapeutic opportunitiesAyman Ali Mohammed Alameen, Hayder Mutter Al-Kuraishy, Ahmed M Abdelaziz, Ali Ismail Al-Gareeb, Ali K. Albuhadily, Gaber El‐Saber Batiha · 2026 · Life Sciences
- Synthesis and Preliminary Biological Evaluation of New Phthalazinone Derivatives with PARP-1 and Cholinesterase Inhibitory ActivitiesZhen-Li Min, Lin Yu, Chengzhi Gao, Zhuyong Wang, Ruifeng Zhang, Yajun Chen · 2022 · Letters in Drug Design & Discovery
- Elucidating the impact of parthanatos-related microRNAs on the tumoral immune microenvironment and clinical outcome in low-grade gliomasPenglei Zhu, Hao Wu, Buyi Zheng, Hua Wang, Yi Zou · 2024 · Discover Oncology
- A novel signature based on twelve programmed cell death patterns to predict the prognosis of lung adenocarcinomaShao-Kun Yu · 2024 · American Journal of Translational Research
- Plant programmed cell death in the context of diversity and evolution of PCDTatiana V. Doronina, Elena Michailovna Lazareva · 2025 · PROTOPLASMA
- Cell Injury and NecrosisJoana C. d’Avila, Stuart Levin, Z.A. Radi · 2017 · Elsevier eBooks
- Regulated Cell DeathWalter Gottlieb Land · 2018 · Springer eBooks
- PARP in the neuropathogenesis of cytomegalovirus infection – Possible role and therapeutic perspectiveSathish Sankar, Vasanth Dhakshinamoorthy, Govindasamy Rajakumar · 2023 · Microbial Pathogenesis
- Analysis from the perspective of cilia: the protective effect of PARP inhibitors on visual function during light-induced damageLin Che, Jingyao Song, Yan Lou, Guangyu Li · 2019 · International Ophthalmology
- Mechanisms of Pancreatic β-Cell Apoptosis in Diabetes and Its TherapiesJames D. Johnson, Yu Hsuan Carol Yang, Dan S. Luciani · 2014 · Springer eBooks
- Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIVRahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death
- Parthanatos: Poly ADP Ribose Polymerase ( PARP )‐Mediated Cell DeathAmos A. Fatokun · 2018
- Cancer Prognosis According to Parthanatos FeaturesAlessandra Messikommer, Bruktawit Maru, Katja Seipel, Peter J.M. Valk, Alexandre P. A. Theocharides, Thomas Pabst, Maureen McKeague, Nathan W. Luedtke · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Poly(ADP-ribose) Polymerase 1 Deficiency Attenuates Amyloid Pathology, Neurodegeneration, and Cognitive Decline in a Familial Alzheimer’s Disease ModelAanishaa Jhaldiyal, Manisha Kumari, Trupti Tripathi, Rizwan Hasan Khan, Justin L. Wang, Lauren C. Guttman, Devanik Biswas, Abhishek Pasupuleti, Akansha Aggarwal, Shraddha Pandya et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Crosstalk between BER and NHEJ in XRCC4-Deficient Cells Depending on hTERT OverexpressionSvetlana V. Sergeeva, Polina S Loshchenova, Dmitry Y. Oshchepkov, Кonstantin E. Orishchenko · 2024 · International Journal of Molecular Sciences
- Preprotective Effects of Cardamomin From Amomum villosum Lour. on H 2 O 2 ‐Induced Oxidative Damage In Vitro and Cerebral Ischemic Stroke In VivoMan Lu Zhu, Dejuan Sun, Hui Wang, Yuxia Li, Hua Li, Lixia Chen · 2025 · Phytotherapy Research
- Identification of mono-ADP-ribose readers using well-defined photoaffinity-based probesFemke L. A. M. van der Heijden, Suzanne A. Weijers, Spyridoula Kondyli, Onno B. Bleijerveld, Michiel Vermeulen, Dmitri V. Filippov · 2025 · RSC Chemical Biology
- Targeting non-apoptotic regulated cell death (RCD) to treat neurodegenerative diseasesWenzhe Zhao, Yue Lai, Zhijia Li, Ziyue Yuan, Zhifeng Wen, Lan Zhang · 2026 · Acta Pharmaceutica Sinica B
- PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease modelAanishaa Jhaldiyal, Manisha Kumari, Lauren C. Guttman, Trupti Tripathi, Mohammed Repon Khan, Justin Wang, Devanik Biswas, Abhishek Pasupuleti, Akansha Aggarwal, Shraddha Pandya et al. · 2026 · Proceedings of the National Academy of Sciences
- An ADPRS variant disrupts ARH3 stability and subcellular localization in children with neurodegeneration and respiratory failureMaxwell Henry Bannister, Sarah Bray, Anjali Aggarwal, Charles John Billington, Hai Dang Nguyen · 2024 · Human Genetics and Genomics Advances
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- WHICH WAY DO YOU PREFER TO DEATH ? Cell Death and Beyond2016 · OMICS International eBooks
- [Effect of hot water extract of Korean ginseng on neuroblastoma cell parthanatos].Yuanbo Guo, Dengwen Zhang, Ruichun Long, Songgui Shan, Qiang Sun, Bin Cai, Sheng Wang · 2020 · PubMed Central
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- Role of Nuclear NAD+ in Retinal HomeostasisEmily E. Brown, Michael J. Scandura, Eric A. Pierce · 2023 · Advances in experimental medicine and biology
- Effects of Normobaric Hypoxia and Adrenergic Blockade over 72 h on Cardiac Function in RatsElias Neubert, Beate Raßler, Annekathrin Hoschke, Coralie Raffort, Aida Salameh · 2023 · International Journal of Molecular Sciences
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- AMPK Limits MNNG-Induced Parthanatos by Inhibiting BH3-Only Protein BimShuhei Hamano, Tomoe Maruyama, Midori Suzuki, Maki Mitsuya, Takumi Yokosawa, Yusuke Hirata, Atsushi Matsuzawa, Takuya Noguchi · 2025 · International Journal of Molecular Sciences
- The Role of PARPs in DNA Strand Break RepairStuart L. Rulten, Françoise Dantzer, Keith W. Caldecott · 2015 · Cancer drug discovery and develogment/Cancer drug discovery and development
- Cell Death: Many Causes and Many EffectsDennis V. Cokkinos · 2019 · Springer eBooks
- Mechanisms of Pancreatic β-Cell Apoptosis in Diabetes and Its TherapiesJames D. Johnson, Yu H. C. Yang, Dan S. Luciani · 2014 · Springer eBooks
- Arsenite-induced cytotoxicity is regulated by poly-ADP ribose polymerase 1 activation and parthanatos in p53-deficient H1299 cells: The roles of autophagy and p53Keum-Young So, Seon‐Hee Oh · 2023 · Biochemical and Biophysical Research Communications
- PARP-1 negatively regulates nucleolar protein pool and mitochondrial activity: a cell protective mechanismAtanu Ghorai, Soumajit Saha, Basuthkar Jagadeeshwar Rao · 2024 · Genes and Environment
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- usEPs in Pre-clinical Cancer TreatmentStephen J. Beebe · 2021 · Series in bioengineering
- Abscopal effects induced by localized interventions in oncological patients.E. Ventura, A. Costa, R.B. Dominguez, Gaetano Romano · 2021 · Annals of Research in Oncology
- A Multi-component Bioinformatics Study on the Construction of a Prognostic Signature of Genes Associated with Diverse Programmed Cell Death in Acute Leukemia and a Multi-perspective Mechanism ExplorationXuewu Tang, Zhiteng Yan · 2023 · Research Square
- A novel variant in ADPRS disrupts ARH3 stability and subcellular localization in children with neurodegeneration and respiratory failureMaxwell Henry Bannister, Sarah Bray, Anjali Aggarwal, Charles John Billington, Hai Dang Nguyen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Recognition of mono-ADP ribosylated ARTD10 substrates by ARTD8 macrodomains and acetylation of ARTD10Alexandra H Forst, Bernhard Lüscher · 2014 · RWTH Publications (RWTH Aachen)
- Design, Development, and Evaluation of Tools to Study Cellular ADP-ribose Polymer MetabolismJamin D. Steffen · 2011 · UA Campus Repository (The University of Arizona)
- “Synthetic Lethality”: Molecular Co-targeting to Restore the DNA Repair Mechanisms in Prostate Cancer CellsGennaro Ilardi, Stefania Staibano · 2013 · Springer eBooks
- On the role of innate cell interactions in inflammation and leukemiaRebecca E. Riise · 2015 · Gothenburg University Publications Electronic Archive (Gothenburg University)
- Immune escape in chronic leukemiaOlle Werlenius · 2015 · Gothenburg University Publications Electronic Archive (Gothenburg University)
- The in vitro effects of Herpes simplex virus and Rubella virus on autophagyKata Pásztor · 2014
- Heterologous production and DNA binding activity of Trypanosoma cruzi poly(ADP ribose) polymeraseSaman Nosheen · 2013
- Role of cardiac FoxO1 in conditions of insulin resistance, nutrient excess, and diabetesPrasanth Puthanveetil · 2012 · cIRcle (University of British Columbia)