Parthanatos, a messenger of death

David, Karen Kate·2009·Frontiers in Bioscience

Cited by (451)

Items 301–400 of 451

  1. Impact of Parthanatos on the Increased Risk of Onset and Mortality in Male Patients With Pulmonary Hypertension
    Zhen-Chun Lv, Fei Li, Lan Wang, Qin-Hua Zhao, Gong-Su Gang, Yue Wu, Yuqing Miao, Ping Yuan · 2021 · American Journal of Men s Health
  2. The Role of Regulatory Cell Death in Vitiligo
    Lyu-Ye Liu, Sijia He, Chen Zhao, Man Ge, Chunyi Lyu, Dandan Gao, Ji-Peng Yu, Menghan Cai, Jinxiang Yuan, Junling Zhang · 2023 · DNA and Cell Biology
  3. Inactivation of necroptosis-promoting protein MLKL creates a therapeutic vulnerability in colorectal cancer cells
    Peijia Jiang, Sandhya Chipurupalli, Byong Hoon Yoo, Xiaoyang Liu, Kirill V. Rosen · 2025 · Cell Death and Disease
  4. Comprehensive analysis of regulated cell death pathways: intrinsic disorder, protein–protein interactions, and cross-pathway communication
    Oleksandr Sorokin, Frank Hause, Alice Wedler, Tala Alakhras, Theresa Bauchspiess, Anne Dietrich, Wiebke F. Günther, Coninika Guha, Kingsley Benjamin Obika, Joshua Kraft et al. · 2025 · APOPTOSIS
  5. iPCD: A Comprehensive Data Resource of Regulatory Proteins in Programmed Cell Death
    Dachao Tang, Cheng Han, Shaofeng Lin, Xiaodan Tan, Weizhi Zhang, Di Peng, Chenwei Wang, Yu Xue · 2022 · Cells
  6. 4′-O-methylbavachalcone alleviates ischemic stroke injury by inhibiting parthanatos and promoting SIRT3
    Hong-qing Chen, Q G Zhang, Xin-yuan Zhang, Xiang-bing Zeng, Jin‐Wen Xu, Shuang Ling · 2024 · European Journal of Pharmacology
  7. PARP-1 dependent cell death pathway (Parthanatos) mediates early brain injury after subarachnoid hemorrhage
    Yuwei Han, Chenchen Wang, Xiaoming Li, Guobiao Liang · 2024 · European Journal of Pharmacology
  8. Apoptosis and Autophagy
    Francesco Merolla · 2013 · Springer eBooks
  9. Ethanol-induced changes in poly (ADP ribose) polymerase and neuronal developmental gene expression
    David P. Gavin, Handojo Kusumo, Rajiv P. Sharma, Marina Guizzetti · 2016 · Neuropharmacology
  10. The effects of nicotinamide on reinstatement to cocaine seeking in male and female Sprague Dawley rats
    Emily A. Witt, Kathryn J. Reissner · 2019 · Psychopharmacology
  11. Evaluation of ABT-888 in the amelioration of α-synuclein fibril-induced neurodegeneration
    Lyndsay Hastings, Arpine Sokratian, Daniel J. Apicco, Christina M. Stanhope, Lindsey Smith, Warren D. Hirst, Andrew B. West, Kaela Kelly · 2022 · Brain Communications
  12. Causes and consequences of DNA double-stranded breaks in cardiovascular disease
    Ali J. Marian · 2024 · Molecular and Cellular Biochemistry
  13. Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy
    Saki Sakakura, Emi Inagaki, Tomoko Sayano, Risa Yamazaki, Noemi Fusaki, Shin Hatou, Masatoshi Hirayama, Kazuo Tsubota, Kazuno Negishi, Hideyuki Okano et al. · 2023 · Regenerative Therapy
  14. Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells
    Faiza Tahia, Sandip Kumar Basu, Amanda Prislovsky, Koushik Mondal, Dejian Ma, Harry Kochat, Kennard Brown, Daniel Stephenson, Charles Edward Chalfant, Nawajes A. Mandal · 2024 · Experimental Eye Research
  15. Parthanatos‐associated proteins are stimulated intraocularly during development of experimental murine cytomegalovirus retinitis in mice with retrovirus‐induced immunosuppression
    Jay J. Oh, Jessica J. Carter, J.G. Nemeno, Richard D. Dix · 2019 · Journal of Medical Virology
  16. Helicobacter pyloriactivation of PARP-1
    Carlos Wolfgang Nossa, Steven R. Blanke · 2010 · Gut Microbes
  17. The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells
    Benigno C. Valdez, Li Yang, David L. Murray, Yan Liu, Yago L. Nieto, Richard E. Champlin, Börje S. Andersson · 2017 · Leukemia & lymphoma/Leukemia and lymphoma
  18. Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying Diseases
    Jean‐Marie Ravel, Luis Cristóbal Monraz Gómez, Nicolas Sompairac, Laurence Calzone, Boris Zhivotovsky, Guido Kroemer, Emmanuel Barillot, Andrei Y. Zinovyev, Inna Kuperstein · 2020 · Cancers
  19. Alzheimer’s disease: a jigsaw puzzle comprised of different types of programmed cell death pieces
    Yu Wang, Dan Mu, Ying Li, Chang Liu, Jianan Feng, Yong Lai, Guanhua Lou · 2025 · Brain Research
  20. Unraveling the intriguing interplay: Exploring the role of lncRNAs in caspase‐independent cell death
    Yusuf Cem Çiftçi, İpek Erdoğan, Bünyamin Akgül · 2024 · Wiley Interdisciplinary Reviews - RNA
  21. Ozone therapy mitigates parthanatos after ischemic stroke
    Jiahui Li, Xiaolei Liu, Zengze Wang, Pengyun Xie, Min Zhu, Hanhui Zhong, Sirui Luo, Jing Yi Tang, Guixi Mo · 2024 · Biological Research
  22. Insight into the machinery that oils chromatin dynamics
    Roni H. G. Wright, Narcís Fernández‐Fuentes, Baldomero Oliva, Miguel Beato · 2016 · Nucleus
  23. Etiology and pathogenesis of Parkinson disease
    Joseph J. Jankovic, Mark Hallett, Michael S. Okun, Cynthia Comella, Stanley Fahn, Jennifer G. Goldman · 2021 · Elsevier eBooks
  24. Chronic NOD2 stimulation by MDP confers protection against parthanatos through M2b macrophage polarization in RAW264.7 cells
    Florencia Celeste Mansilla, María Cruz Miraglia, Silvina Soledad Maidana, Cecilia P. Randazzo, Alejandra Victoria Capozzo · 2024 · Immunobiology
  25. Mono‐ADP‐Ribosylation of Peptides: An Overview of Synthetic and Chemoenzymatic Methodologies
    Hugo Minnee, Jeroen D. C. Codée, Dmitri V. Filippov · 2024 · ChemBioChem
  26. Inhibiting De Novo Biosynthesis of Ceramide by L-Cycloserine Can Prevent Light-Induced Retinal Degeneration in Albino BALB/c Mice
    Faiza Tahia, Dejian Ma, Daniel Stephenson, Sandip Kumar Basu, Nobel A. Del Mar, Nataliya I. Lenchik, Harry Kochat, Kennard Brown, Charles Edward Chalfant, Nawajes A. Mandal · 2024 · International Journal of Molecular Sciences
  27. Poly (ADP‐Ribose) Glycohydrolase‐Dependent dePARylation of PCNA Is Essential for DNA Replication
    Zhenzhen Yan, Qianxi Feng, Xiuhuan Jiang, Xiaoru Han, Zichang Qiao, Yaguang Wang, Xiaoyun Yang, Xiuhua Liu, Xinying Cheng, Shuai Guo et al. · 2025 · The FASEB Journal
  28. Chaperone‐mediated autophagy attenuates H2O2‐induced cardiomyocyte apoptosis by targeting poly (ADP‐ribose) polymerase 1 (PARP1) for lysosomal degradation
    Dandan Zhang, Lai Wei, Yang Liu, Rong Wan, Yang Shen · 2022 · Cell Biology International
  29. Recent Progress in Small-Molecule Inhibitors for Critical Therapeutic Targets of Necroptosis
    Zhennan Fang, Huiqiang Wei, Wenfeng Gou, Leyuan Chen, Changfen Bi, Wenbin Hou, Yiliang Li · 2021 · Future Medicinal Chemistry
  30. Necrosis, Apoptosis, and Autophagy: Mechanisms of Neuronal and Glial Cell Death
    Michael Fricker, Aviva M. Tolkovsky · 2011 · Neuromethods
  31. The role and regulation of cell death in cancer
    Minh Trong Quang, Minh Nam Nguyen, Van Thai Than · 2025 · Progress in molecular biology and translational science
  32. PARP enzyme synthesis of protein-free poly(ADP-ribose): Implications for DNA damage signaling and repair
    Marie-France Langelier, John M. Pascal · 2025 · DNA repair
  33. PARP inhibitors as radiosensitizers: a comprehensive review of preclinical evidence and clinical applications
    Xiaodong Luo, Shuo Gao, Kaiyang Sun, Zhiqiang Dong, Shude Yang · 2025 · Frontiers in Oncology
  34. Unveiling the therapeutic potential of natural-based anticancer compounds inducing non-canonical cell death mechanisms
    Esra Bozgeyi̇k, İbrahim Bozgeyik · 2023 · Pathology - Research and Practice
  35. Creation of signatures and identification of molecular subtypes of glioblastoma based on disulfidptosis-related genes for predicting patient prognosis and immunological activity
    Dongjun Li, Xiaodong Li, Jianfeng Lv, Shaoyi Li · 2024 · Asian Journal of Surgery
  36. CHD1L Regulates Cell Survival in Breast Cancer and Its Inhibition by OTI-611 Impedes the DNA Damage Response and Induces PARthanatos
    Rita Sala, Hector Esquer, Timothy Kellett, Jeffrey T. Kearns, Paul Awolade, Qiong Zhou, Daniel V. LaBarbera · 2024 · International Journal of Molecular Sciences
  37. Karyoptosis as a novel type of UVB-induced regulated cell death
    Weidong Chen, Jiin Byun, Han Chang Kang, Hye Suk Lee, Joo Young Lee, Young Jik Kwon, Yong‐Yeon Cho · 2024 · Free Radical Research
  38. Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivo
    Hidemitsu Nakajima, Masanori Itakura, Keishi Sato, Sunao Nakamura, Yasu‐Taka Azuma, Tadayoshi Takeuchi · 2017 · Biochemical and Biophysical Research Communications
  39. Increased nucleotide metabolism alleviates Alzheimer’s disease pathology
    Yizhou Yu, Michael B. Miller, August Yue Huang, Bryan Wei Zhi Tan, Ivana Celardo, Nuno Santos Leal, Samantha H. Y. Loh, L. Miguel Martins · 2025 · Cell Death and Disease
  40. Programming regulated cell death to engineer whole-tumor-cell vaccines for cancer immunotherapy
    Yingchao Guan, Die Bai, Na Bu, Wenhui Hao, Yasen Maimaitiyiming · 2026 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  41. CHD1L Inhibitor OTI-611 Synergizes with Chemotherapy to Enhance Antitumor Efficacy and Prolong Survival in Colorectal Cancer Mouse Models
    Rita Sala, Hector Esquer, Timothy Kellett, Sophia Clune, Paul Awolade, L. Pike, Qiong Zhou, W. Messersmith, Daniel V. LaBarbera · 2024 · International Journal of Molecular Sciences
  42. Transient Global Cerebral Ischemia Produces Morphologically Necrotic, Not Apoptotic Neurons
    F. Colbourne, R. Auer · 2010 · Springer eBooks
  43. Improved antitumor activity through a tyramidyl maslinic acid derivative. Design and validation as drug-loaded electrospun polymeric nanofibers
    Cristina Luque, María de la Cabeza Fernández, David Fuentes‐Ríos, Ana Luisa Cepero, Rafael Contreras‐Cáceres, Manuel Doña, Gloria Perazzoli, Laura Lozano Chamizo, Marco Filice, Marzia Marciello et al. · 2023 · European Journal of Pharmaceutics and Biopharmaceutics
  44. The assessment of an in-vitro model for evaluating the role of PARP in ethanol-mediated hepatotoxicity
    Richard Harbison, JaymeP Coyle, Amora Mayo-PEREZ, M Bourgeois, G Johnson, S Morris · 2015 · International Journal of Critical Illness and Injury Science
  45. Poly (ADP-ribose) induces α-synuclein aggregation in neuronal-like cells and interacts with phosphorylated α-synuclein in post mortem PD samples
    Laura N. Puentes, Zsofia Lengyel‐Zhand, Ji Youn Lee, Chia‐Ju Hsieh, Mark E. Schneider, Kimberly J. Edwards, Kelvin C. Luk, Virginia M.‐Y. Lee, John Q. Trojanowski, Robert H. Mach · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  46. Host regulator PARP1 contributes to sex differences and immune responses in a mouse model of tuberculosis
    Stefanie Krug, Alvaro A. Ordoñez, Mariah H. Klunk, Bong Gu Kang, Sanjay Kumar Jain, Ted M. Dawson, Valina Lynn Dawson, William R. Bishai · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  47. CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential
    Sophia Clune, Paul Awolade, Hector Esquer, Qiong Zhou, Daniel V. LaBarbera · 2025 · Journal of Experimental & Clinical Cancer Research
  48. Dysregulated Intracellular Signaling in the Pathogenesis of Vitiligo: An Update on Emerging Therapeutic Strategies
    Ramona Marrapodi, Alberto Marini, Barbara Bellei · 2025 · Biomedicines
  49. SARM1 executes neuronal parthanatos and promotes excitotoxic cell death
    Tong Wu, Liya Yuan, Yo Sasaki, Si Jia Chen, William Buchser, A. Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt · 2026 · Neuron
  50. Programmed cell death in lung cancer: mechanisms, immune responses, and therapeutics
    Yang Liu, Qingxin Chen, Jiayu Xu, Hao Chi · 2026 · APOPTOSIS
  51. Targeting PARP1-dependent parthanatos in Alzheimer's disease: Mechanisms and therapeutic opportunities
    Ayman Ali Mohammed Alameen, Hayder Mutter Al-Kuraishy, Ahmed M Abdelaziz, Ali Ismail Al-Gareeb, Ali K. Albuhadily, Gaber El‐Saber Batiha · 2026 · Life Sciences
  52. Synthesis and Preliminary Biological Evaluation of New Phthalazinone Derivatives with PARP-1 and Cholinesterase Inhibitory Activities
    Zhen-Li Min, Lin Yu, Chengzhi Gao, Zhuyong Wang, Ruifeng Zhang, Yajun Chen · 2022 · Letters in Drug Design & Discovery
  53. Elucidating the impact of parthanatos-related microRNAs on the tumoral immune microenvironment and clinical outcome in low-grade gliomas
    Penglei Zhu, Hao Wu, Buyi Zheng, Hua Wang, Yi Zou · 2024 · Discover Oncology
  54. A novel signature based on twelve programmed cell death patterns to predict the prognosis of lung adenocarcinoma
    Shao-Kun Yu · 2024 · American Journal of Translational Research
  55. Plant programmed cell death in the context of diversity and evolution of PCD
    Tatiana V. Doronina, Elena Michailovna Lazareva · 2025 · PROTOPLASMA
  56. Cell Injury and Necrosis
    Joana C. d’Avila, Stuart Levin, Z.A. Radi · 2017 · Elsevier eBooks
  57. Regulated Cell Death
    Walter Gottlieb Land · 2018 · Springer eBooks
  58. PARP in the neuropathogenesis of cytomegalovirus infection – Possible role and therapeutic perspective
    Sathish Sankar, Vasanth Dhakshinamoorthy, Govindasamy Rajakumar · 2023 · Microbial Pathogenesis
  59. Analysis from the perspective of cilia: the protective effect of PARP inhibitors on visual function during light-induced damage
    Lin Che, Jingyao Song, Yan Lou, Guangyu Li · 2019 · International Ophthalmology
  60. Mechanisms of Pancreatic β-Cell Apoptosis in Diabetes and Its Therapies
    James D. Johnson, Yu Hsuan Carol Yang, Dan S. Luciani · 2014 · Springer eBooks
  61. Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV
    Rahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death
  62. Parthanatos: Poly ADP Ribose Polymerase ( PARP )‐Mediated Cell Death
    Amos A. Fatokun · 2018
  63. Cancer Prognosis According to Parthanatos Features
    Alessandra Messikommer, Bruktawit Maru, Katja Seipel, Peter J.M. Valk, Alexandre P. A. Theocharides, Thomas Pabst, Maureen McKeague, Nathan W. Luedtke · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Poly(ADP-ribose) Polymerase 1 Deficiency Attenuates Amyloid Pathology, Neurodegeneration, and Cognitive Decline in a Familial Alzheimer’s Disease Model
    Aanishaa Jhaldiyal, Manisha Kumari, Trupti Tripathi, Rizwan Hasan Khan, Justin L. Wang, Lauren C. Guttman, Devanik Biswas, Abhishek Pasupuleti, Akansha Aggarwal, Shraddha Pandya et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  65. Crosstalk between BER and NHEJ in XRCC4-Deficient Cells Depending on hTERT Overexpression
    Svetlana V. Sergeeva, Polina S Loshchenova, Dmitry Y. Oshchepkov, Кonstantin E. Orishchenko · 2024 · International Journal of Molecular Sciences
  66. Preprotective Effects of Cardamomin From Amomum villosum Lour. on H 2 O 2 ‐Induced Oxidative Damage In Vitro and Cerebral Ischemic Stroke In Vivo
    Man Lu Zhu, Dejuan Sun, Hui Wang, Yuxia Li, Hua Li, Lixia Chen · 2025 · Phytotherapy Research
  67. Identification of mono-ADP-ribose readers using well-defined photoaffinity-based probes
    Femke L. A. M. van der Heijden, Suzanne A. Weijers, Spyridoula Kondyli, Onno B. Bleijerveld, Michiel Vermeulen, Dmitri V. Filippov · 2025 · RSC Chemical Biology
  68. Targeting non-apoptotic regulated cell death (RCD) to treat neurodegenerative diseases
    Wenzhe Zhao, Yue Lai, Zhijia Li, Ziyue Yuan, Zhifeng Wen, Lan Zhang · 2026 · Acta Pharmaceutica Sinica B
  69. PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease model
    Aanishaa Jhaldiyal, Manisha Kumari, Lauren C. Guttman, Trupti Tripathi, Mohammed Repon Khan, Justin Wang, Devanik Biswas, Abhishek Pasupuleti, Akansha Aggarwal, Shraddha Pandya et al. · 2026 · Proceedings of the National Academy of Sciences
  70. An ADPRS variant disrupts ARH3 stability and subcellular localization in children with neurodegeneration and respiratory failure
    Maxwell Henry Bannister, Sarah Bray, Anjali Aggarwal, Charles John Billington, Hai Dang Nguyen · 2024 · Human Genetics and Genomics Advances
  71. The degree of caspase-3 aggregation determines the selectivity of arsenic-induced cell death
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  72. WHICH WAY DO YOU PREFER TO DEATH ? Cell Death and Beyond
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  73. [Effect of hot water extract of Korean ginseng on neuroblastoma cell parthanatos].
    Yuanbo Guo, Dengwen Zhang, Ruichun Long, Songgui Shan, Qiang Sun, Bin Cai, Sheng Wang · 2020 · PubMed Central
  74. Cerebro-Cardiovascular Diseases
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  75. usEP Induce Regulated Cell Death Mechanisms
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  76. Role of Nuclear NAD+ in Retinal Homeostasis
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  77. Effects of Normobaric Hypoxia and Adrenergic Blockade over 72 h on Cardiac Function in Rats
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  78. Pervasive loss of regulated necrotic cell death genes in elephants, hyraxes, and sea cows ( Paenungualta )
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  79. Unveiling the vital role of OGG1 in inflammation, vascular endothelial damage, and cell death in obstetric and gynecological diseases
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  80. Evolving methodologies for identification and differentiation of regulated cell death modalities
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  81. AMPK Limits MNNG-Induced Parthanatos by Inhibiting BH3-Only Protein Bim
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  82. The Role of PARPs in DNA Strand Break Repair
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  83. Cell Death: Many Causes and Many Effects
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  84. Mechanisms of Pancreatic β-Cell Apoptosis in Diabetes and Its Therapies
    James D. Johnson, Yu H. C. Yang, Dan S. Luciani · 2014 · Springer eBooks
  85. Arsenite-induced cytotoxicity is regulated by poly-ADP ribose polymerase 1 activation and parthanatos in p53-deficient H1299 cells: The roles of autophagy and p53
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  86. PARP-1 negatively regulates nucleolar protein pool and mitochondrial activity: a cell protective mechanism
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  87. Leveraging programmed cell death patterns to predict prognosis and therapeutic sensitivity in OSCC
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  88. Programmed cell death in human respiratory syncytial virus infection
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  89. usEPs in Pre-clinical Cancer Treatment
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  91. A Multi-component Bioinformatics Study on the Construction of a Prognostic Signature of Genes Associated with Diverse Programmed Cell Death in Acute Leukemia and a Multi-perspective Mechanism Exploration
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  92. A novel variant in ADPRS disrupts ARH3 stability and subcellular localization in children with neurodegeneration and respiratory failure
    Maxwell Henry Bannister, Sarah Bray, Anjali Aggarwal, Charles John Billington, Hai Dang Nguyen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Recognition of mono-ADP ribosylated ARTD10 substrates by ARTD8 macrodomains and acetylation of ARTD10
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  94. Design, Development, and Evaluation of Tools to Study Cellular ADP-ribose Polymer Metabolism
    Jamin D. Steffen · 2011 · UA Campus Repository (The University of Arizona)
  95. “Synthetic Lethality”: Molecular Co-targeting to Restore the DNA Repair Mechanisms in Prostate Cancer Cells
    Gennaro Ilardi, Stefania Staibano · 2013 · Springer eBooks
  96. On the role of innate cell interactions in inflammation and leukemia
    Rebecca E. Riise · 2015 · Gothenburg University Publications Electronic Archive (Gothenburg University)
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  100. Role of cardiac FoxO1 in conditions of insulin resistance, nutrient excess, and diabetes
    Prasanth Puthanveetil · 2012 · cIRcle (University of British Columbia)