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Cited by 127Neuroendocrine Tumor Research AdvancesRadiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and Applications

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

First-in-Humans Study of the SSTR Antagonist 177Lu-DOTA-LM3 for Peptide Receptor Radionuclide Therapy in Patients with Metastatic Neuroendocrine Neoplasms: Dosimetry, Safety, and Efficacy

Open access
Baum, Richard P., Zhang, Jingjing, Schuchardt, Christiane, Müller, Dirk, Mäcke, Helmut·2021·Journal of Nuclear Medicine
DOI 10.2967/jnumed.120.258889PMC PMC8612334
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Abstract

Educational Aims To illustrate the common mechanisms limiting exercise tolerance in patients with chronic lung and heart disease To highlight the impact of lung and heart disease on daily physical activity levels To outline the effects of cardiopulmonary rehabilitation on functional capacity in patients with chronic lung and heart disease To discuss an innovative tele-rehabilitation intervention using information and communications technologies to improve functional capacity in patients with chronic lung and heart disease Summary Shortness of breath associated with cardiorespiratory abnormalities and peripheral muscle discomfort are the major factors that limit exercise capacity in patients with chronic obstructive pulmonary disease (COPD) and those with congestive heart failure (CHF). Both of these symptoms negatively impact on patients’ daily physical activity levels. In turn, poor daily physical activity is commonly associated with increased rates of morbidity and mortality. Cardiopulmonary rehabilitation programmes partially reverse muscle weakness and dysfunction and increase functional capacity in both COPD and CHF. However, benefits gained from participation in cardiopulmonary rehabilitation programmes are regressing soon after the completion of these programmes. Moreover, several barriers limit access and uptake of cardiopulmonary rehabilitation programmes by eligible patients. A potential solution to the underutilisation of cardiopulmonary rehabilitation is the implementation of tele-rehabilitation interventions at home using information and communications technologies. Thus, tele-rehabilitation may be useful to encourage and educate patients with COPD or CHF on how best to maintain and/or further enhance daily physical activity levels.

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Metadata

Authors
Baum, R. P., Zhang, J., Schuchardt, C., Müller, D., & Mäcke, H.
Affiliations
  • Zentralklinik Bad Berka (DE)
  • National University of Singapore (SG)
  • University Medical Center Freiburg (DE)
ORCID
Venue
Journal of Nuclear Medicine
Publisher
Society of Nuclear Medicine
Published
2021-03-05
Volume
62
Issue
11
Pages
1571-1581
ISSN
  • 0161-5505 (ISSN-L)
  • 2159-662X
DOI
10.2967/jnumed.120.258889
PMC
PMC8612334
OpenAlex
W3133553083
Cited by
127
References
38
Citations by year
2026: 35 · 2025: 32 · 2024: 18 · 2023: 19 · 2022: 15 · 2021: 8
FWCI
10.80
Type
journal article
Language
en
Open access
Locations
  • Journal of Nuclear Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Neuroendocrine Tumor Research Advances
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiopharmaceutical Chemistry and Applications
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
Keywords
somatostatin receptor antagonists, peptide receptor radionuclide therapy, metastatic neuroendocrine tumors, dosimetry, treatment safety, treatment efficacy
MeSH terms
Adult, Aged, Female, Humans, Lutetium, Male, Middle Aged, Neoplasm Metastasis, Organometallic Compounds, Radioisotopes, Radiometry, Safety, Octreotide, Treatment Outcome, Receptors, Somatostatin, Neuroendocrine Tumors

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