The potential therapeutic applications and mechanisms of action of Cryptomphalus aspersa (snail) extracts in dermatology and wound healing

Abstract

Cryptomphalus aspersa, commonly known as the garden snail, has emerged as a promising therapeutic agent in the fields of dermatology and wound healing. This review explores the diverse therapeutic applications and underlying mechanisms of action of Cryptomphalus aspersa extracts. With a rich history in traditional medicine and growing scientific evidence supporting their efficacy, snail extracts offer multifaceted benefits including anti-inflammatory, antioxidant, collagen-stimulating, and immunomodulatory activities. In dermatology, snail extracts have shown promise in managing conditions such as acne vulgaris, atopic dermatitis, photoaging, and hyperpigmentation, while also demonstrating efficacy in promoting wound healing in various types of wounds, including full-thickness and chronic wounds. Mechanistically, snail extracts modulate inflammatory pathways, neutralize oxidative stress, stimulate collagen synthesis, and regulate immune responses, contributing to their therapeutic effects. While the potential of Cryptomphalus aspersa extracts is vast, further research and clinical trials are warranted to establish their efficacy and safety profiles for specific dermatological conditions and wound types. Overall, Cryptomphalus aspersa extracts represent a novel and promising approach in dermatology and wound healing, offering a natural and multifaceted solution for improving skin health and promoting tissue repair.