Intestinal Infarction in COVID-19 Pandemic: A Case Series
Open accessAbstract
Novel coronavirus disease 2019 (COVID-19) as a potential health risk factor continues to spread worldwide. Although common symptoms include headache and respiratory symptoms, some studies have suggested that COVID-19 may cause coagulation disorders and thrombolytic events, disrupt blood flow to the visceral organs, and cause some complications such as mesenteric ischemia. The authors reported four cases of acute mesenteric ischemia associated with COVID-19 confirmed in patients hospitalized in Imam Reza Hospital (a COVID-19 referral center in Mashhad University of Medical Sciences, Mashhad, Iran). The authors described the pathological findings that may be associated with this infection. The authors collected clinical data, imaging, microscopic, and operative findings of four patients with severe COVID-19 infection and evidence of intestinal necrosis. These four cases of severe COVID-19 pneumonia simultaneously showed intestinal necrosis during the infection process, indicating a relationship between coronavirus and mesenteric vascular events. Physicians should be aware of thrombosis symptoms in the digestive system in patients with severe COVID-19.
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The typical presentation in patients with acute mesenteric ischemia is severe abdominal pain out of proportion to physical signs along with bowel emptying, nausea, vomiting and diarrhea that might progress into peritonitis and bowel perforation.
“The typical presentation in patients with acute mesenteric ischemia is severe abdominal pain that is out of proportion of physical signs along with bowel emptying, nausea, vomitimg and Diarrhea that might progress into peritonitis and bowel perforation [1, 2, 4, 5].”
From Outcome of Acute Mesenteric Ischemia in Patients with COVID 19 Infection Our Experience at Royal Medical Services (2022) · cites this paper as [2]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredThromboembolic complications have been reported increasingly during the COVID-19 pandemic, including acute mesenteric ischemia, which is a challenging and life-threatening condition accompanied by high rates of mortality and morbidity.
“However, Thromboembolic complications has been reported inceasingly during the corona virus pandemic, including acute mesenteric ischemia (AMI) which is a challenging and life threatening condition that is accompanied by high rates of mortality and morbidity [1, 2].”
From Outcome of Acute Mesenteric Ischemia in Patients with COVID 19 Infection Our Experience at Royal Medical Services (2022) · cites this paper as [2]
The Abstract and Discussion (page numbers unavailable) report COVID-19-associated thromboembolic disease and four cases of acute mesenteric ischemia. The Introduction calls the resulting intestinal necrosis severe and deadly, and all four patients died. The paper does not establish that thromboembolic complications were reported increasingly during the pandemic or document high morbidity rates. (LLM, conf=0.85)
Experimental — accuracy not yet measuredThromboembolic complications in association with severe COVID-19 pneumonic infection have been recognized more frequently, with acute mesenteric ischemia being one of the most devastating, accompanied by high morbidity with mortality rates reaching 60% to 80%.
“Thromboembolic complications, in association with severe COVID 19 pneumonic infection, has been recognized more frequenctly with acute mesenteric ischemia being one of the most devastating, accompanied by high morbidity with mortality rates reaching up to 60% to 80% among these patients [1-3].”
From Outcome of Acute Mesenteric Ischemia in Patients with COVID 19 Infection Our Experience at Royal Medical Services (2022) · cites this paper as [2]
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Cites
Clair, D. G., & Beach, J. M. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1503884 · Cited by 589 · see citing works
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Research works printed but not linked: 12
- [2]Merad M Martin JC Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages Nature reviews immunology. 2020 20 6 355 62 PMC7201395 32376901
- [3]Lippi G Plebani M Henry BM Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis Clin Chim Acta. 2020 506 145 8 32178975 PMC7102663
- [4]Fabre O Rebet O Carjaliu I Radutoiu M Gautier L Hysi I Severe Acute Proximal Pulmonary Embolism and COVID-19: A Word of Caution Ann Thorac Surg. 2020 110 5 e409 e11 32305287 PMC7162739
- [6]Zhou B She J Wang Y Ma X Venous thrombosis and arteriosclerosis obliterans of lower extremities in a very severe patient with 2019 novel coronavirus disease: a case report J Thromb Thrombolysis. 2020 50 1 229 32 32306290 PMC7165253
- [7]Cui S Chen S Li X Liu S Wang F Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia J Thromb Haemost. 2020 18 6 1421 4 32271988 PMC7262324
- [8]Iba T Levy JH Derangement of the endothelial glycocalyx in sepsis J Thromb Haemost. 2019 17 2 283 94 30582882
- [9]Varga Z Flammer AJ Steiger P Haberecker M Andermatt R Zinkernagel AS Endothelial cell infection and endotheliitis in COVID-19 Lancet. 2020 395 10234 1417 8 32325026 PMC7172722
- [10]Smith SA Mutch NJ Baskar D Rohloff P Docampo R Morrissey JH Polyphosphate modulates blood coagulation and fibrinolysis Proc Natl Acad Sci U S A. 2006 103 4 903 8 16410357 PMC1347979
- [11]Ignat M Philouze G Aussenac-Belle L Faucher V Collange O Mutter D Small bowel ischemia and SARS-CoV-2 infection: an underdiagnosed distinct clinical entity Surgery. 2020 168 1 14 6 32473831 PMC7198136
- [12]Bussani R Schneider E Zentilin L Collesi C Ali H Braga L Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology EBioMedicine. 2020 61 103104 33158808 PMC7677597
- [13]Buja LM Wolf DA Zhao B Akkanti B McDonald M Lelenwa L The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): Report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities Cardiovasc Pathol. 2020 48 107233 32434133 PMC7204762
- [14]Emert R Shah P Zampella JG COVID-19 and hypercoagulability in the outpatient setting Thromb Res. 2020 192 122 3 32473495 PMC7245205
Cited by
Sorted by citations
COVID-19 and intestinal ischemia: a multicenter case series
Sarkardeh, M., Meftah, E., Mohammadzadeh, N., Koushki, J., & Sadrzadeh, Z. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.879996 · Cited by 13 · see citing works
Self-citationAlmasafeh, E. S., Samarneh, T. H. A., Alkhawaldeh, H. I., & Khamis, F. I. (2022) · Scholars Journal of Applied Medical Sciences · doi:10.36347/sjams.2022.v10i08.019
- Authors
- Sarkardeh, M., Dalili, A., Tayyebi Meibodi, N., Izanlu, M., Davari-Sani, S. J., Moghaddamzade, S., Jamalinik, M., Hosseini, S. J., Koushki, J., & Abedia, A.
- Affiliations
- Mashhad University of Medical Sciences (IR)
- Sabzevar University of Medical Sciences (IR)
- Islamic Azad University, Tehran (IR)
- Corresponding author
- Izanlu, Mostafa
- Venue
- Iranian Journal of Pathology
- Publisher
- Farname, Inc.
- Published
- 2022-01-01
- Volume
- 17
- Issue
- 1
- Pages
- 85-90
- ISSN
- 1735-5303 (ISSN-L)
- 2345-3656
- PMC
- PMC8794570
- OpenAlex
- W4206641509
- Cited by
- 10
- References
- 1
- Citations by year
- 2025: 1 · 2023: 3 · 2022: 6
- FWCI
- 2.39
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Iranian journal of pathology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Mashhad University of Medical Sciences
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Ophthalmology › Retinal and Optic Conditions
- Keywords
- COVID-19 pandemic, intestinal infarction, mesenteric ischemia, intestinal necrosis, thrombosis, coagulopathy, mesenteric vascular occlusion, severe COVID-19 pneumonia, gastrointestinal complications
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