The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Massage Therapy is Associated with Enhancement of the Immune System's Cytotoxic Capacity
Abstract
Twenty-nine gay men (20 HIV+, 9 HIV-) received daily massages for one month. A subset of 11 of the HIV+ subjects served as a within subject control group (one month with and without massages). Major immune findings for the effects of the month of massage included a significant increase in Natural Killer Cell number, Natural Killer Cell Cytotoxicity, soluble CD8, and the cytotoxic subset of CD8 cells. There were no changes in HIV disease progression markers (CD4, CD4/CD8 ratio, Beta-2 microglobulin, neopterin). Major neuroendocrine findings, measured via 24 hour urines included a significant decrease in cortisol, and nonsignificant trends toward decrease of catecholamines. There were also significant decreases in anxiety and increases in relaxation which were significantly correlated with increases in NK cell number. Thus, there appears to be an increase in cytotoxic capacity associated with massage. Implications for HIV+ men as those with other illnesses, particularly cancer, are discussed.
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Cites
Unconventional medicine in the United States-Prevalence, costs, and patterns of use
Eisenberg, D. M., Kessler, R. C., Foster, C., Norlock, F. E., Calkins, D. R., & Delbanco, T. L. (1993) · New England Journal of Medicine · doi:10.1056/nejm199301283280406 · Cited by 4,177
Cited by
Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight.
Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A. R., & Updegraff, J. A. (2000) · Psychological Review · doi:10.1037/0033-295x.107.3.411 · Cited by 3,308
A Meta-Analysis of Massage Therapy Research.
Moyer, C. A., Rounds, J., & Hannum, J. W. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.1.3 · Cited by 665
Cortisol decreases and serotonin and dopamine increase following massage therapy
FIELD, T., HERNANDEZ-REIF, M., DIEGO, M., SCHANBERG, S., & KUHN, C. (2005) · International Journal of Neuroscience · doi:10.1080/00207450590956459 · Cited by 574
Self-citationMassage increases oxytocin and reduces adrenocorticotropin hormone in humans.
(2012) · PubMed · Cited by 215
Stress Management and Psychoneuroimmunology in HIV Infection
Antoni, M. H. (2003) · CNS Spectrums · doi:10.1017/s1092852900023440 · Cited by 57
Metadata
- Authors
- Ironson, G., Field, T., Scafidi, F., Hashimoto, M., Kumar, M., Kumar, A., Price, A., Goncalves, A., Burman, I., Tetenman, C., Patarca, R., & Fletcher, M. A.
- Venue
- International Journal of Neuroscience
- Publisher
- Informa UK Limited
- Published
- 1996-01
- Volume
- 84
- Issue
- 1-4
- Pages
- 205-217
- ISSN
- 0020-7454 (ISSN-L)
- 1543-5245
- OpenAlex
- W2035279900
- Cited by
- 294
- References
- 1
- FWCI
- 3.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Massage Therapy is Associated with Enhancement of the Immune System's Cytotoxic Capacity. https://app.cochat.ai/papers/10.3109/00207459608987266
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- Ironson, G., Field, T., Scafidi, F., Hashimoto, M., Kumar, M., Kumar, A., Price, A., Goncalves, A., Burman, I., Tetenman, C., Patarca, R., & Fletcher, M. A. (1996). Massage Therapy is Associated with Enhancement of the Immune System's Cytotoxic Capacity. International Journal of Neuroscience. https://doi.org/10.3109/00207459608987266
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
