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Results of Screening, Rescreening, and Follow-up in a Prospective Randomized Study for Detection of Colorectal Cancer by Fecal Occult Blood Testing: Results for 68,308 Subjects
Abstract
All 68,308 inhabitants of Göteborg born between 1918 and 1931 were randomly divided into a test and a control group. The subjects in the test group were invited to perform Hemoccult II fecal occult blood testing on 3 days and to repeat the test after 16 to 24 months. In the prevalence screening 21,347 (63%) performed the test, and in the rescreening 19,991 (60%). Investigation of the 942 (4.4%) with positive tests in the prevalence screening showed 47 cancers and 129 subjects with adenomas > or = 1.0 cm. In the rescreening 5.1% had a positive test, and 34 cancers and 122 subjects with adenomas (> or = 1.0 cm) were found among those. Cancer had also been diagnosed in 19 subjects in the interval between the two screening occasions and in 15 subjects among the non-responders. Forty-four cancers had been diagnosed in the control group during the same period. Cancers detected by screening were at a less advanced stage than in the control group. It is too early to show any effect of screening on mortality from colorectal cancer.
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Cited by
Lin, J. S., Bowles, E. J. A., Williams, S. B., & Morrison, C. C. (2017) · JAMA · doi:10.1001/jama.2017.0562 · Cited by 1,082
Lin, J. S., Perdue, L. A., Henrikson, N. B., Bean, S. I., & Blasi, P. R. (2021) · JAMA · doi:10.1001/jama.2021.4417 · Cited by 650
Zorzi, M., Fedeli, U., Schievano, E., Bovo, E., Guzzinati, S., Baracco, S., Fedato, C., Saugo, M., & Dei Tos, A. P. (2015) · Gut · doi:10.1136/gutjnl-2014-307508 · Cited by 302
Impact of Screening Program on Incidence of Colorectal Cancer: A Cohort Study in Italy
Rossi, P. G., Vicentini, M., Sacchettini, C., Di Felice, E., Caroli, S., Ferrari, F., Mangone, L., Pezzarossi, A., Roncaglia, F., Campari, C., et al. (2015) · American Journal of Gastroenterology · doi:10.1038/ajg.2015.240 · Cited by 143
Metadata
- Authors
- Kewenter, J., Brevinge, H., Engarás, B., Haglind, E., & Ährén, C.
- Venue
- Scandinavian Journal of Gastroenterology
- Publisher
- Informa UK Limited
- Published
- 1994-01
- Volume
- 29
- Issue
- 5
- Pages
- 468-473
- ISSN
- 0036-5521 (ISSN-L)
- 1502-7708
- OpenAlex
- W2009164177
- Cited by
- 249
- References
- 0
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Results of Screening, Rescreening, and Follow-up in a Prospective Randomized Study for Detection of Colorectal Cancer by Fecal Occult Blood Testing: Results for 68,308 Subjects. https://app.cochat.ai/papers/10.3109/00365529409096840
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- Kewenter, J., Brevinge, H., Engarás, B., Haglind, E., & Ährén, C. (1994). Results of Screening, Rescreening, and Follow-up in a Prospective Randomized Study for Detection of Colorectal Cancer by Fecal Occult Blood Testing: Results for 68,308 Subjects. Scandinavian Journal of Gastroenterology. https://doi.org/10.3109/00365529409096840
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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