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Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
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“Methoxsalen was reportedly an inhibitor of both CYPs 2A6 and 1A2 (Ono et al., 1996).”
From Piperine Is a Mechanism-Based Inactivator of CYP3A (2020) · cites this paper as Ono et al., 1996
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Cites
The Carbon Monoxide-binding Pigment of Liver Microsomes
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Yamano, S., Aoyama, T., McBride, O. W., Hardwick, J. P., Gelboin, H. V., & Gonzalez, F. J. (1989) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09090-x · Cited by 95
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Research works printed but not linked: 39
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Cited by
Benzodiazepines in epilepsy: Pharmacology and pharmacokinetics
Riss, J., Cloyd, J., Gates, J., & Collins, S. (2008) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2008.01004.x · Cited by 511
Effects of the Antifungal Agents on Oxidative Drug Metabolism: Clinical Relevance
Venkatakrishnan, K., von Moltke, L. L., & Greenblatt, D. J. (2000) · Clinical Pharmacokinetics · doi:10.2165/00003088-200038020-00002 · Cited by 508
An Overview of the Evidence and Mechanisms of Herb–Drug Interactions
Fasinu, P. S., Bouic, P. J., & Rosenkranz, B. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00069 · Cited by 221
Yamaori, S., Kushihara, M., Yamamoto, I., & Watanabe, K. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.01.028 · Cited by 165
(2001) · Indian Journal of Pharmacology · Cited by 52
Metadata
- Authors
- Ono, S., Hatanaka, T., Hotta, H., Satoh, T., Gonzalez, F. J., & Tsutsui, M.
- Venue
- Xenobiotica
- Publisher
- Informa UK Limited
- Published
- 1996-01
- Volume
- 26
- Issue
- 7
- Pages
- 681-693
- ISSN
- 0049-8254
- 1366-5928
- Cited by
- 233
- References
- 3
- Language
- en
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- CoChat. (2026). Citation check: Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. https://app.cochat.ai/papers/10.3109/00498259609046742
- The paper
- Ono, S., Hatanaka, T., Hotta, H., Satoh, T., Gonzalez, F. J., & Tsutsui, M. (1996). Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica. https://doi.org/10.3109/00498259609046742
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.