Familial inheritance of endometriosis in a British population. A case control study
Abstract
SummaryThe incidence of endometriosis in the tirst degree relatives of 64 women with a visual diagnosis of endometriosis, the index group, was compared with 128 case controls with no known endometriosis. Data was collected by interview and attempts made to independently verify the diagnosis of the relatives. The number with a first degree relative with endometriosis was six (94 per cent) in the index group which was higher (P < 0-05, Fisher's exact test) than the two women (1-6 per cent) in the control group. The 95 per cent coincidence limits for the difference in percentages were 0-36 to 15-3 per cent. Within the total population of tirst degree relatives the percentage with endometriosis was also higher (P < 0-05) in the index group (5-5 per cent) compared with the control group (0-7 per cent); coincidence limits for difference 0-6 to 8-5 per cent. This verifies previous reports of a higher incidence of endometriosis in the first degree relatives of suffers of endometriosis, suggesting there may be a famililar tendency.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The risk of developing endometriosis is 6%-9% higher in first-degree relatives of women with endometriosis.
“The risk of developing endometriosis is 6%-9% higher in first-degree relatives of women with endometriosis (34,35)”
From Pathogenesis of endometriosis: The genetic/epigenetic theory (2019) · cites this paper as [35]
Prevalence of endometriosis is increased by 6%-9% in first-degree relatives and by 15% for severe disease.
“Prevalence is increased by 6%-9% in first degree relatives (163, 164) and by 15% for severe disease (165, 166).”
From Pathogenesis of deep endometriosis (2017) · cites this paper as [164]
The citation lists haven’t been fetched yet
References 6 · Cited by 97
- Authors
- Coxhead, D., & Thomas, E. J.
- Affiliations
- Princess Anne Hospital (GB)
- ORCID
- Thomas, E. J.
- Venue
- Journal of Obstetrics and Gynaecology
- Publisher
- Informa UK Limited
- Published
- 1993-01
- Volume
- 13
- Issue
- 1
- Pages
- 42-44
- ISSN
- 0144-3615 (ISSN-L)
- 1364-6893
- OpenAlex
- W2222842226
- Cited by
- 97
- References
- 6
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 1 · 2013: 2
- FWCI
- 0.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Obstetrics and Gynaecology (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, familial inheritance, first-degree relatives, genetic risk, incidence, British women
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
