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Chitosan: Properties, preparations and application to microparticulate systems
Abstract
Chitosan, a hydrophilic biopolymer, is obtained industrially by hydrolysing the aminoacetyl groups of chitin. It is a natural, non-toxic, biodegradable polysaccharide available as solution, flake, fine powder, bead and fibre. The sources, biochemical aspects, structure and chemical modification, physico-chemical and functional properties, and applications of chitosan have been investigated extensively in the literature. In this paper, the attractive properties and broad applications of chitosan-based microparticles, their versatile properties, different preparation methods, and pharmaceutical and biopharmaceutical applications are reviewed.
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Cited by
Recent advances on chitosan-based micro- and nanoparticles in drug delivery
Agnihotri, S. A., Mallikarjuna, N. N., & Aminabhavi, T. M. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.08.010 · Cited by 2,586
Zargar, V., Asghari, M., & Dashti, A. (2015) · ChemBioEng Reviews · doi:10.1002/cben.201400025 · Cited by 957
Chitosan: some pharmaceutical and biological aspects - an update
Singla, A. K., & Chawla, M. (2001) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357011776441 · Cited by 784
Chitosan scaffolds: Interconnective pore size and cartilage engineering
GRIFFON, D., SEDIGHI, M., SCHAEFFER, D., EURELL, J., & JOHNSON, A. (2006) · Acta Biomaterialia · doi:10.1016/j.actbio.2005.12.007 · Cited by 351
Biodegradable Polymers for Microencapsulation of Drugs
Park, J., Ye, M., & Park, K. (2005) · Molecules · doi:10.3390/10010146 · Cited by 317
Metadata
- Authors
- Kas, H. S.
- Venue
- Journal of Microencapsulation
- Publisher
- Informa UK Limited
- Published
- 1997-01
- Volume
- 14
- Issue
- 6
- Pages
- 689-711
- ISSN
- 0265-2048 (ISSN-L)
- 1464-5246
- OpenAlex
- W2156311649
- Cited by
- 411
- References
- 0
- FWCI
- 3.90
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
