The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Taxanes: A New Class of Antitumor Agents
Abstract
Taxanes belong to a new group of antineoplastic agents with a novel mechanism of action for a cytotoxic drug. They promote microtubule assembly and stabilize the microtubules. Paclitaxel, the first agent in this group to become available, was isolated from the Pacific yew, Taxus brevifolia, in 1971. In preclinical and clinical studies, paclitaxel and its semisynthetic analog docetaxel exhibit significant antitumor activity. This review deals with the physicochemical properties, pharmacology, and results of preclinical and clinical trials of the taxanes.
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Cites
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Taxol and Taxane Production by Taxomyces andreanae , an Endophytic Fungus of Pacific Yew
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Hypersensitivity reactions from taxol.
Weiss, R. B., Donehower, R. C., Wiernik, P. H., Ohnuma, T., Gralla, R. J., Trump, D. L., Baker, J. R., Van Echo, D. A., Von Hoff, D. D., & Leyland-Jones, B. (1990) · Journal of Clinical Oncology · doi:10.1200/jco.1990.8.7.1263 · Cited by 1,174
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Cited by
In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy
Kim, S. C., Kim, D. W., Shim, Y. H., Bang, J. S., Oh, H. S., Kim, S. W., & Seo, M. H. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00275-9 · Cited by 734
Review: Tubulin Function, Action of Antitubulin Drugs, and New Drug Development
Pellegrini, F., & Budman, D. R. (2005) · Cancer Investigation · doi:10.1081/cnv-200055970 · Cited by 313
Preparation, characterization, and pharmacokinetics of liposomal docetaxel for oral administration
Kim, J. H., Shin, D. H., & Kim, J.-S. (2018) · Archives of Pharmacal Research · doi:10.1007/s12272-018-1046-y · Cited by 37
Impact of taxanes on androgen receptor signaling
Dong, Y., Bai, S., & Zhang, B. (2019) · Asian Journal of Andrology · doi:10.4103/aja.aja_37_18 · Cited by 26
A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models
Rezania, V., Coombe, D., & Tuszynski, J. A. (2016) · Theoretical Biology and Medical Modelling · doi:10.1186/s12976-016-0034-5 · Cited by 24
Metadata
- Authors
- Huizing, M. T., Misser, V. H. S., Pieters, R. C., ten Bokkel Huinink, W. W., Veenhof, C. H. N., Vermorken, J. B., Pinedo, H. M., & Beijnen, J. H.
- Venue
- Cancer Investigation
- Publisher
- Informa UK Limited
- Published
- 1995-01
- Volume
- 13
- Issue
- 4
- Pages
- 381-404
- ISSN
- 0735-7907 (ISSN-L)
- 1532-4192
- OpenAlex
- W2137303860
- Cited by
- 285
- References
- 77
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Taxanes: A New Class of Antitumor Agents. https://app.cochat.ai/papers/10.3109/07357909509031919
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- Huizing, M. T., Misser, V. H. S., Pieters, R. C., ten Bokkel Huinink, W. W., Veenhof, C. H. N., Vermorken, J. B., Pinedo, H. M., & Beijnen, J. H. (1995). Taxanes: A New Class of Antitumor Agents. Cancer Investigation. https://doi.org/10.3109/07357909509031919
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
