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Cited by 870

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Generation and Application of Data on Biological Variation in Clinical Chemistry

Fraser, Gallum G., Harris, Eugene K.·1989·Critical Reviews in Clinical Laboratory Sciences

Abstract

Most clinical chemical analytes vary in a random manner around a homeostatic set point. Replicate analyses of a series of specimens collected from a group of subjects allows estimation of analytical, within and between subject components of variation. The preferred experimental procedures and statistical methods for evaluation of data and analysis of variance are described; a detailed example is provided in the Appendix. The many uses of data on biological variation in clinical chemistry are reviewed, including setting analytical goals, deciding the significance of changes in serial results from an individual, evaluating the utility of conventional population-based reference values in patient management, and other applications.

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Crossref · 10.3109/10408368909106595

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Metadata

Authors
Fraser, G. G., & Harris, E. K.
Venue
Critical Reviews in Clinical Laboratory Sciences
Published
1989-01
Volume
27
Issue
5
Pages
409-437
ISSN
  • 1040-8363 (ISSN-L)
  • 1549-781X
OpenAlex
W2117872000
Cited by
870
References
1
FWCI
5.52
Type
journal article
Language
en
Open access
closed

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