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Cited by 728

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

DNA Gyrase: Structure and Function

Reece, Richard J., Maxwell, Anthony·1991·Critical Reviews in Biochemistry and Molecular Biology

Abstract

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. Gyrase belongs to a class of enzymes known as topoisomerases that are involved in the control of topological transitions of DNA. The mechanism by which gyrase is able to influence the topological state of DNA molecules is of inherent interest from an enzymological standpoint. In addition, much attention has been focused on DNA gyrase as the intracellular target of a number of antibacterial agents as a paradigm for other DNA topoisomerases. In this review we summarize the current knowledge concerning DNA gyrase by addressing a wide range of aspects of the study of this enzyme.

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Metadata

Authors
Reece, R. J., & Maxwell, A.
Venue
Critical Reviews in Biochemistry and Molecular Biology
Published
1991-01
Volume
26
Issue
3-4
Pages
335-375
ISSN
  • 0045-6411 (ISSN-L)
  • 1040-9238
  • 1549-7798
OpenAlex
W2142775912
Cited by
728
References
1
FWCI
2.98
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: DNA Gyrase: Structure and Function. https://app.cochat.ai/papers/10.3109/10409239109114072
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Reece, R. J., & Maxwell, A. (1991). DNA Gyrase: Structure and Function. Critical Reviews in Biochemistry and Molecular Biology. https://doi.org/10.3109/10409239109114072

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