The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Elevated neutrophil to lymphocyte ratio predicts survival in advanced pancreatic cancer
Abstract
BACKGROUND: Elevated neutrophil to lymphocyte ratio (NLR) is linked with worse survival in many malignancies, whereas its association with pancreatic cancer (PC) remains unclear. METHODS: We retrospectively reviewed 95 patients with locally advanced or metastatic PC receiving gemcitabine-based chemotherapy. The prognostic value of NLR was evaluated. RESULTS: Elevated pretreatment NLR (> 5) was observed in 16 out of 89 eligible patients, which was identified as an independent prognostic factor for overall survival (OS). The median OS for patients with elevated and normal NLR were 2.4 months and 7.7 months, respectively (p < 0.001). CONCLUSIONS: Elevated NLR is a predictor of shorter survival in patients with advanced PC.
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New Guidelines to Evaluate the Response to Treatment in Solid Tumors
Therasse, P., Arbuck, S. G., Eisenhauer, E. A., Wanders, J., Kaplan, R. S., Rubinstein, L., Verweij, J., Van Glabbeke, M., van Oosterom, A. T., Christian, M. C., et al. (2000) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/92.3.205 · Cited by 15,660
Cited by
Templeton, A. J., McNamara, M. G., Šeruga, B., Vera-Badillo, F. E., Aneja, P., Ocaña, A., Leibowitz-Amit, R., Sonpavde, G., Knox, J. J., Tran, B., et al. (2014) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/dju124 · Cited by 2,829
Templeton, A. J., Ace, O., McNamara, M. G., Al-Mubarak, M., Vera-Badillo, F. E., Hermanns, T., Šeruga, B., Ocaña, A., Tannock, I. F., & Amir, E. (2014) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-0146 · Cited by 719
Goldstein, D., El-Maraghi, R. H., Hammel, P., Heinemann, V., Kunzmann, V., Sastre, J., Scheithauer, W., Siena, S., Tabernero, J., Teixeira, L., et al. (2015) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dju413 · Cited by 658
Neutrophils Promote Liver Metastasis via Mac-1–Mediated Interactions with Circulating Tumor Cells
Spicer, J. D., McDonald, B., Cools-Lartigue, J. J., Chow, S. C., Giannias, B., Kubes, P., & Ferri, L. E. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-2393 · Cited by 401
Mei, Z., Shi, L., Wang, B., Yang, J., Xiao, Z., Du, P., Wang, Q., & Yang, W. (2017) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2017.05.005 · Cited by 304
Metadata
- Authors
- An, X., Ding, P.-R., Li, Y.-H., Wang, F.-H., Shi, Y.-X., Wang, Z.-Q., He, Y.-J., Xu, R.-H., & Jiang, W.-Q.
- Venue
- Biomarkers
- Publisher
- Informa UK Limited
- Published
- 2010-07-05
- Volume
- 15
- Issue
- 6
- Pages
- 516-522
- ISSN
- 1354-750X (ISSN-L)
- 1366-5804
- OpenAlex
- W2047945295
- Cited by
- 244
- References
- 1
- FWCI
- 4.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- An, X., Ding, P.-R., Li, Y.-H., Wang, F.-H., Shi, Y.-X., Wang, Z.-Q., He, Y.-J., Xu, R.-H., & Jiang, W.-Q. (2010). Elevated neutrophil to lymphocyte ratio predicts survival in advanced pancreatic cancer. Biomarkers. https://doi.org/10.3109/1354750x.2010.491557
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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