The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of paraphilias
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Objectives The primary aim of these guidelines was to evaluate the role of pharmacological agents in the treatment and management of paraphilia, with a focus on the treatment of adults males. Because such treatments are not delivered in isolation, the role of specific psychosocial and psychotherapeutic interventions was also briefly covered. These guidelines are intended for use in clinical practice by clinicians who diagnose and treat patients with paraphilia. The aim of these guidelines is to improve the quality of care and to aid physicians in clinical decisions. Methods The aim of these guidelines was to bring together different views on the appropriate treatment of paraphilias from experts representing different continents. To achieve this aim, an extensive literature search was conducted using the English language literature indexed on MEDLINE/PubMed (1990-2009 for SSRIs) (1969-2009 for antiandrogen treatments), supplemented by other sources, including published reviews. Results Each treatment recommendation was evaluated and discussed with respect to the strength of evidence for its efficacy, safety, tolerability and feasibility. Conclusions An algorithm was proposed with six levels of treatment for different categories of paraphilias.
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There is an association between antilibidinal hormonal medication and mood changes (Thibaut 2010; Gooren 2011).
“The latter is important given the association between antilibidinal hormonal medication and mood changes (Thibaut 2010; Gooren 2011)”
From Pharmacological interventions for those who have sexually offended or are at risk of offending (2015) · cites this paper as Thibaut 2010
Currently, given the extant knowledge, the answer to whether treatment needs to be life-long to maintain a reduction in sexual offending can only be gleaned from expert opinion.
“Currently, given the extant knowledge, the answer to this question can only be gleaned from expert opinion (Thibaut 2010).”
From Pharmacological interventions for those who have sexually offended or are at risk of offending (2015) · cites this paper as Thibaut 2010
The algorithmic treatment regimens of Grubin 2008 and Thibaut 2010 remain at the lowest level of the evidence hierarchy when not supported by properly conducted randomised controlled trials.
“the algorithmic treatment regimens of Grubin 2008 and Thibaut 2010 no doubt have their value, but, from the perspective of evidence-based practice, these recommendations - however sensible - remain at the lowest level of the evidence hierarchy when not supported by properly conducted randomised controlled trials.”
From Pharmacological interventions for those who have sexually offended or are at risk of offending (2015) · cites this paper as Thibaut 2010
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- Authors
- Thibaut, F., Barra, F. D. L., Gordon, H., Cosyns, P., Bradford, J. M. W., & the WFSBP Task Force on Sexual Disorders
- Affiliations
- Hôpital Charles-Nicolle (FR)
- Clínica Las Condes (CL)
- University of Oxford (GB)
- University of Antwerp (BE)
- University of Ottawa (CA)
- Corresponding author
- Thibaut, Florence
- Venue
- The World Journal of Biological Psychiatry
- Publisher
- Informa UK Limited
- Published
- 2010-01
- Volume
- 11
- Issue
- 4
- Pages
- 604-655
- ISSN
- 1562-2975 (ISSN-L)
- 1814-1412
- OpenAlex
- W2129253219
- Cited by
- 274
- References
- 304
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 7 · 2023: 9 · 2022: 11 · 2021: 18 · 2020: 41 · 2019: 13 · 2018: 28 · 2017: 16 · 2016: 21 · 2015: 21 · 2014: 30 · 2013: 21 · 2012: 7
- FWCI
- 16.11
- Type
- journal article
- Language
- en
- Open access
- Licence
- cc-by-nc-nd
- Locations
- The World Journal of Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Universidad de Chile (submittedVersion, cc-by-nc-nd)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- paraphilias, pharmacotherapy, selective serotonin reuptake inhibitors, antiandrogen therapy, psychosocial interventions, psychotherapy, treatment algorithm, adult male, treatment efficacy and safety
- MeSH terms
- Adult, Algorithms, Androgen Antagonists, Biological Psychiatry, Drug Therapy, Humans, Male, Paraphilic Disorders, Global Health
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