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Risk assessment of engineered nanomaterials: a review of available data and approaches from a regulatory perspective

Hristozov, Danail R., Gottardo, Stefania, Critto, Andrea, Marcomini, Antonio·2012·Nanotoxicology

Abstract

It has been largely recognised that substantial limitations and uncertainties make the conventional risk assessment (RA) of chemicals unfeasible to apply to engineered nanomaterials (ENMs) today, which leaves the regulators with little support in the near term. The aim of this paper is to discuss the state of the art in the area of the RA of nanomaterials, focusing on the available data and approaches. There is a paucity of reliable information in the online safety databases and the literature is dominated by (eco)toxicity studies, while the nano-exposure research lags behind. Most of the reviewed nano-RA approaches are designed to serve as preliminary risk screening and/or research prioritisation tools and are not intended to support regulatory decision making. In this context, we recommend to further study the possibilities to apply complementary/alternative tools for near-term RA of ENMs in order to facilitate their timely regulation, using the data that are currently available in the literature.

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Metadata

Authors
Hristozov, D. R., Gottardo, S., Critto, A., & Marcomini, A.
Venue
Nanotoxicology
Published
2012-01-09
Volume
6
Issue
8
Pages
880-898
ISSN
  • 1743-5390 (ISSN-L)
  • 1743-5404
OpenAlex
W2145857667
Cited by
167
References
0
FWCI
7.53
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Risk assessment of engineered nanomaterials: a review of available data and approaches from a regulatory perspective. https://app.cochat.ai/papers/10.3109/17435390.2011.626534
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Hristozov, D. R., Gottardo, S., Critto, A., & Marcomini, A. (2012). Risk assessment of engineered nanomaterials: a review of available data and approaches from a regulatory perspective. Nanotoxicology. https://doi.org/10.3109/17435390.2011.626534

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