Surgical procedures and their cost estimates among women with newly diagnosed endometriosis: A US database study
Open accessAbstract
OBJECTIVE: This descriptive study assessed the rate and costs of surgical procedures among newly diagnosed endometriosis patients. METHODS: Utilizing the Medstat MarketScan database, commercially insured women aged 18-45 with endometriosis newly diagnosed during 2006-2007 were identified. Each endometriosis patient was matched to four women without endometriosis (population controls) based on age and region of residence. Surgical procedures received during the 12 months post-diagnosis were assessed. Costs of surgical procedures were the amount paid by the insurance companies. RESULTS: This study identified 15,891 women with newly diagnosed endometriosis and 63,564 population controls. More than 65% of endometriosis patients received an endometriosis-related surgical procedure within 1 year of the initial diagnosis. The most common procedure was therapeutic laparoscopy (31.6%), followed by abdominal hysterectomy (22.1%) and vaginal hysterectomy (6.8%). Prevalence and type of surgery performed varied by patient age, including a hysterectomy rate of approximately 16% in patients younger than 35 and 37% among patients aged 35-45 years. Average costs ranged from $4,289 (standard deviation [SD]: $3,313) for diagnostic laparoscopy to $11,397 (SD: $8,749) for abdominal hysterectomy. LIMITATIONS: Diagnosis of endometriosis cannot be validated against medical records, and information on the severity of endometriosis-related symptoms is not available in administrative claims data. CONCLUSIONS: Over 65% of patients had endometriosis-related surgical procedures, including hysterectomy, within 1 year of being diagnosed with endometriosis. The cost of surgical procedures related to endometriosis places a significant financial burden on the healthcare system.
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With a high recurrence rate (~50%) after conservative surgery, up to 37% of premenopausal women will eventually undergo radical surgery in the form of total hysterectomy and bilateral salpingo-oophorectomy.
“With a high recurrence rate (~50%) after conservative surgery, which involves complete excision of endometriosis without hysterectomy [1,2], up to 37% of premenopausal women will eventually undergo the radical surgery in the form of total hysterectomy and bilateral salpingo-oophorectomy (TH-BSO) as a more definitive and permanent solution [3].”
From HRT in Women Undergoing Pelvic Clearance for Endometriosis—A Case Report and a National Survey (2023) · cites this paper as [3]
The Surgery rates section reports that 36.9% of patients aged 35–45 had an abdominal or vaginal hysterectomy within one year of diagnosis, supporting a figure near 37% for that age group. It does not establish that 37% of premenopausal women eventually undergo total hysterectomy with bilateral salpingo-oophorectomy: Table 2 lists oophorectomy separately at 2.7%. The recurrence estimate is attached to other citations in the citing sentence. (LLM, conf=0.89)
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References 12 · Cited by 47
Research works printed but not linked: 1
- [13]13. Merrill RM. Hysterectomy surveillance in the United States, 1997 through 2005. Medical science monitor: international medical journal of experimental and clinical research 2008;14:CR24-31
- Authors
- Fuldeore, M., Chwalisz, K., Marx, S., Wu, N., Boulanger, L., Ma, L., & Lamothe, K.
- Affiliations
- Abbott (United States) (US)
- Corresponding author
- Wu, N.
- Venue
- Journal of Medical Economics
- Publisher
- Informa Healthcare
- Published
- 2011-01
- Volume
- 14
- Issue
- 1
- Pages
- 115-123
- ISSN
- 1369-6998 (ISSN-L)
- 1941-837X
- OpenAlex
- W2064501451
- Cited by
- 47
- References
- 12
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 6 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 5 · 2016: 6 · 2014: 4 · 2012: 2
- FWCI
- 2.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Medical Economics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, surgical procedures, health care costs, hysterectomy, abdominal hysterectomy, vaginal hysterectomy, diagnostic laparoscopy, therapeutic laparoscopy, women's health, health insurance claims
- MeSH terms
- Adolescent, Adult, Costs and Cost Analysis, Endometriosis, Female, Humans, Medical Audit, Middle Aged, Surgical Procedures, Operative, United States, Comorbidity, Databases, Factual, Young Adult
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