The DOI matches its Crossref record.
Therapeutic Effect of Lisuride Maleate on Post-stroke Depression.
Open accessAbstract
Twenty post-stroke depressive patients who obtained more than 11 points on Self-Rating Questionnaire for Depression, were treated with 0.075 mg/day lisuride maleate for 12 weeks. The drug effect on depression was evaluated quantitatively by the Hamilton Rating Scale for Depression. The relationships between brain CT or MRI and SRQ-D score were investigated in 24 subjects. More than 80% of post-stroke depressive patients improved after lisuride maleate treatment for 8 or 12 weeks. In particular, depressed mood, hypobulia, sleep disturbance, anxiety, etc. were significantly improved compared to the baseline condition. As for the relationships with CT and/or MRI findings, the group with moderate to severe brain atrophy had a significantly higher grade of depressive state than those without.
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In the citing paper
“Lisuride, a non-hallucinogenic structural analog of LSD, has been shown to have an antidepressant properties in the clinic”
From Psychedelics and Other Psychoplastogens for Treating Mental Illness. (2021) · cites this paper as [242]
Citations
Cited by
Psychedelics and Other Psychoplastogens for Treating Mental Illness.
Vargas, M. V., Meyer, R., Avanes, A. A., Rus, M., & Olson, D. E. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.727117 · Cited by 166
Metadata
- Authors
- Hougaku, H., Matsumoto, M., Hata, R., Handa, N., Imaizumi, M., Sugitani, Y., Yoneda, S., Etani, H., Sueyoshi, K., Kusunoki, M., Uyama, O., & Kamada, T.
- Affiliations
- The University of Osaka (JP)
- Venue
- Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
- Publisher
- The Japan Geriatrics Society
- Published
- 1994
- Volume
- 31
- Issue
- 1
- Pages
- 52-59
- ISSN
- 0300-9173 (ISSN-L)
- OpenAlex
- W2332481096
- Cited by
- 16
- References
- 0
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 4 · 2022: 2 · 2021: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- ja
- Open access
- diamond
- doi.org
- Locations
- Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Keywords
- post-stroke depression, brain atrophy, antipsychotic drugs, depression severity, neuroimaging, sleep disorders, anxiety, depressive mood
- MeSH terms
- Aged, Cerebrovascular Disorders, Depression, Female, Humans, Lisuride, Male, Middle Aged
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
