The DOI matches its Crossref record; 177 of the 195 references it cites were found in a registry or an index.
Proteolytic Enzymes and Their Relation to Cheese Ripening and Flavor: An Overview
Open accessAbstract
Proteolytic events taking place during cheese ripening are described, and the characteristics of the various proteolytic systems involved are reviewed.Some emphasis is placed on the proteolytic enzymes from starter bacteria because these, in particular, have been subjects of recent and current research.In cheese, the concerted action of residual milk-clotting enzyme, indigenous milk proteinases, and starter proteinases provides suitable substrates for the starter peptidases, which ultimately generate small peptides and free amino acids.Deviations from such a delicately balanced process may lead to deviations from the desired cheese texture and flavor.A bitter flavor defect may develop in the ripening cheese when the degradation of slowly accumulating bitter peptides by suitable peptidases is inhibited.Cheese flavor is thought to be mainly generated by the further, nonproteolytic conversion of amino acids via enzymic and nonenzymic reactions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The high PA characterizes most of the vegetable proteases, which, especially during beginning of cheeses ripening, continue to hydrolyze the caseins causing the appearance of short peptides, which can have a bitter taste [80].”
From Plant Milk-Clotting Enzymes for Cheesemaking (2022) · cites this paper as [80]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“In long-ripened cheeses, it has also been observed that the autolysis of SLAB can provide sufficient nutrients to support the growth of non-starter LAB (NSLAB) in vitro [18,53,73,77,93,99,100,101,102].”
From Microbiota of Cheese Ecosystems: A Perspective on Cheesemaking (2025) · cites this paper as [101]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Hydrophobic Effect: Formation of Micelles and Biological Membranes
Tanford, C. (1991) · Medical Entomology and Zoology · Cited by 3,327
Polymeric stabilization of colloidal dispersions
Napper, D. H. (1983) · Medical Entomology and Zoology · Cited by 2,279
Cheese: Chemistry, Physics and Microbiology
Fox, P. F. (1993) · Springer eBooks · doi:10.1007/978-1-4615-2648-3 · Cited by 1,425
Developments in dairy chemistry—1
Cheeseman, G. C. (1983) · Food Chemistry · doi:10.1016/0308-8146(83)90108-5 · Cited by 917
The hydrophobic effect: Formation of micelles and biological membranes
Gruen, D. W. R., & Haydon, D. A. (1980) · Journal of Colloid and Interface Science · doi:10.1016/0021-9797(80)90338-0 · Cited by 713
Proteolysis During Cheese Manufacture and Ripening
Fox, P. F. (1989) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(89)79246-8 · Cited by 593
Proteinases in normal bovine milk and their action on caseins
Andrews, A. T. (1983) · Journal of Dairy Research · doi:10.1017/s0022029900032519 · Cited by 593
On the Stability of Casein Micelles
Walstra, P. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78875-3 · Cited by 558
Texture development during cheese ripening
Lawrence, R. C., Creamer, L. K., & Gilles, J. (1987) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(87)80207-2 · Cited by 511
Advances in the microbiology and biochemistry of cheese and fermented milk
Davies, F. L., & Law, B. A. (1984) · Cited by 378
Genetics and Molecular Biology of Streptococci, Lactococci, and Enterococci
Dunny, G. M., Cleary, P. P., & McKay, L. L. (1991) · Cited by 353
Proteolytic enzymes of dairy starter cultures
Thomas, T. D., & PRITCHARD, G. G. (1987) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1987.tb02464.x · Cited by 285
Association of caseins and casein micelle structure.
Schmidt, D. G. (1982) · Cited by 246
Grufferty, M. B., & Fox, P. F. (1988) · Journal of Dairy Research · doi:10.1017/s0022029900033409 · Cited by 232
The Enzymatic Coagulation of Milk
Dalgleish, D. G. (1993) · Cheese: Chemistry, Physics and Microbiology · doi:10.1007/978-1-4615-2650-6_3 · Cited by 216
Primary Proteolysis of Cheese Proteins During Ripening. A Review
Grappin, R., Rank, T. C., & OLSON, N. F. (1985) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(85)80855-9 · Cited by 216
Proteolytic systems in lactic acid bacteria
Law, B. A., & Kolstad, J. (1983) · Antonie van Leeuwenhoek · doi:10.1007/bf00399500 · Cited by 210
Nucleotide sequence of the cell wall proteinase gene of Streptococcus cremoris Wg2.
Kok, J., Leenhouts, K. J., Haandrikman, A. J., Ledeboer, A. M., & Venema, G. (1988) · Applied and Environmental Microbiology · doi:10.1128/aem.54.1.231-238.1988 · Cited by 199
determination of plasmin in dairy products
Richardson, B. C., & Pearce, K. N. (1981) · Journal of Dairy Science and Technology · Cited by 195
Genetics of the proteolytic system of lactic acid bacteria
Kok, J. (1990) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1990.tb04877.x · Cited by 190
Korycka-Dahl, M., Dumas, B. R., Chêne, N., & Martal, J. (1983) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(83)81848-7 · Cited by 172
Vos, P., Simons, G., Siezen, R. J., & de Vos, W. M. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)80036-9 · Cited by 168
Vos, P., van Asseldonk, M., van Jeveren, F., Siezen, R. J., Simons, G., & de Vos, W. M. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.5.2795-2802.1989 · Cited by 168
Visser, S., Exterkate, F. A., Slangen, C. J., & de Veer, G. J. C. M. (1986) · Applied and Environmental Microbiology · doi:10.1128/aem.52.5.1162-1166.1986 · Cited by 160
Self-citationThe impact of lactic acid bacteria on cheese flavor
Olson, N. F. (1990) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1990.tb04884.x · Cited by 160
Proteolysis of caseins and the proteose-peptone fraction of bovine milk
Andrews, A. T., & Alichanidis, E. (1983) · Journal of Dairy Research · doi:10.1017/s0022029900023116 · Cited by 155
(1981) · Cited by 154
Generation of Swiss Cheese Flavor Components by the Reaction of Amino Acids with Carbonyl Compounds
Griffith, R., & Hammond, E. G. (1989) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(89)79150-5 · Cited by 142
Purification and Characterization of an Aminopeptidase from Lactococcus lactis subsp. cremoris Wg2
Tan, P. S. T., & Konings, W. N. (1990) · Applied and Environmental Microbiology · doi:10.1128/aem.56.2.526-532.1990 · Cited by 140
Gripon, J. C. (1999) · Springer eBooks · doi:10.1007/978-1-4615-2800-5_4 · Cited by 136
Influence of sodium chloride on the proteolysis of casein by rennet and by pepsin
Fox, P. F., & Walley, B. F. (1971) · Journal of Dairy Research · doi:10.1017/s0022029900019282 · Cited by 135
Jw, A., & Dulley (1982) · Australian Journal of Dairy Technology · Cited by 135
Comparison of Bovine Milk Protease with Plasmin
Kaminogawa, S., Mizobuchi, H., & YAMAUCHI, K. (1972) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.36.2163 · Cited by 134
Plasmin-mediated proteolysis of casein in bovine milk.
Eigel, W. N., Hofmann, C. J., Chibber, B. A., Tomich, J. M., Keenan, T. W., & Mertz, E. T. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.5.2244 · Cited by 128
Influence of Volatile and Nonvolatile Fractions on Intensity of Cheddar Cheese Flavor
McGugan, W. A., Emmons, D. B., & Armond, E. L. (1979) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(79)83258-0 · Cited by 127
Weinstein, M., & Doolittle, R. F. (1972) · Biochimica et Biophysica Acta (BBA) - Enzymology · doi:10.1016/0005-2744(72)90250-1 · Cited by 126
(1987) · Cited by 115
Identification of a gene required for maturation of an extracellular lactococcal serine proteinase.
Haandrikman, A. J., Kok, J., Laan, H., Soemitro, S., Ledeboer, A. M., Konings, W. N., & Venema, G. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.5.2789-2794.1989 · Cited by 114
Parliment, T. H., & Croteau, R. (1986) · ACS symposium series · doi:10.1021/bk-1986-0317 · Cited by 113
Mayo, B., Kok, J., Venema, K., Bockelmann, W., Teuber, M., Reinke, H., & Venema, G. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.1.38-44.1991 · Cited by 113
Location of Peptidases Outside and Inside the Membrane of Streptococcus cremoris
Exterkate, F. A. (1984) · Applied and Environmental Microbiology · doi:10.1128/aem.47.1.177-183.1984 · Cited by 108
Geis, A., Bockelmann, W., & Teuber, M. (1985) · Applied Microbiology and Biotechnology · doi:10.1007/bf02660123 · Cited by 107
Boerrigter, I. J., Baankreis, R., & de Vos, W. M. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.9.2555-2561.1991 · Cited by 105
Zevaco, C., Monnet, V., & Gripon, J. C. (1990) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1990.tb02886.x · Cited by 105
Nardi, M., Chopin, M., Chopin, A., Marie‐Madeleine, C. A. L. S., & Gripon, J. C. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.1.45-50.1991 · Cited by 103
Kiefer-Partsch, B., Bockelmann, W., Geis, A., & Teuber, M. (1989) · Applied Microbiology and Biotechnology · doi:10.1007/bf00252531 · Cited by 103
Specificity of plasmin towards bovine αs2-casein
Bars, D. L., & Gripon, J. C. (1989) · Journal of Dairy Research · doi:10.1017/s002202990002940x · Cited by 100
Observations on plasmin activity in cheese
Farkye, N. Y., & Fox, P. F. (1990) · Journal of Dairy Research · doi:10.1017/s0022029900027060 · Cited by 98
Bartels, H. J., Johnson, M. E., & Olson, N. F. (1987) · Milk science international/Milchwissenschaft · Cited by 98
Purification and Characterization of an Aminopeptidase from Lactococcus lactis subsp. cremoris AM2
Neviani, E., Boquien, C., Monnet, V., Thanh, L. P., & Gripon, J. C. (1989) · Applied and Environmental Microbiology · doi:10.1128/aem.55.9.2308-2314.1989 · Cited by 96
(1983) · Medical Entomology and Zoology · Cited by 95
Self-citationMicrobial catabolism of amino acids during cheese ripening
Hemme, D., Bouillanne, C., Métro, F., & Desmazeaud, M. (1982) · HAL · Cited by 95
Purification and Characterization of a Dipeptidase from Streptococcus cremoris Wg2
van Boven, A., Tan, P. S. T., & Konings, W. N. (1988) · Applied and Environmental Microbiology · doi:10.1128/aem.54.1.43-49.1988 · Cited by 94
Purification and Some Properties of a Membrane-Bound Aminopeptidase A from Streptococcus cremoris
Exterkate, F. A., & de Veer, G. J. C. M. (1987) · Applied and Environmental Microbiology · doi:10.1128/aem.53.3.577-583.1987 · Cited by 91
Steffen, C., Eberhard, P., Bosset, J. O., & Rüegg, M. (1999) · Springer eBooks · doi:10.1007/978-1-4615-2800-5_3 · Cited by 87
Purification and characterization of an endopeptidase from Lactococcus lactis subsp. cremoris Wg2
Tan, P. S. T., Pos, K. M., & Konings, W. N. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.12.3593-3599.1991 · Cited by 84
Effect of Bovine Plasmin on αs1 -B and κ-A Caseins
Eigel, W. N. (1977) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(77)84043-5 · Cited by 80
Kiwaki, M., Ikemura, H., Shimizu‐Kadota, M., & Hiroshima, A. (1989) · Molecular Microbiology · doi:10.1111/j.1365-2958.1989.tb00181.x · Cited by 79
Purification and Characterization of a Tripeptidase from Lactococcus lactis subsp. cremoris Wg2
Bosman, B. W., Tan, P. S. T., & Konings, W. N. (1990) · Applied and Environmental Microbiology · doi:10.1128/aem.56.6.1839-1843.1990 · Cited by 78
Engineering of the Lactococcus lactis serine proteinase by construction of hybrid enzymes
Vos, P., Boerrigter, I. J., Buist, G., Haandrikman, A. J., Nijhuis, M., de Reuver, M. B., Siezen, R. J., Venema, G., de Vos, W. M., & Kok, J. (1991) · "Protein Engineering, Design and Selection" · doi:10.1093/protein/4.4.479 · Cited by 77
Mechanism of Proteinase Release from Lactococcus lactis subsp. cremoris Wg2
Laan, H., & Konings, W. N. (1989) · Applied and Environmental Microbiology · doi:10.1128/aem.55.12.3101-3106.1989 · Cited by 76
Visser, F. M. W. (1977) · doi:10.18174/198202 · Cited by 76
Exterkate, F. (1990) · Applied Microbiology and Biotechnology · doi:10.1007/bf00176654 · Cited by 75
Humbert, G., & Alais, C. (1979) · Journal of Dairy Research · doi:10.1017/s002202990001760x · Cited by 75
Purification and characterization of aminopeptidase A from Lactococcus lactis subsp. lactis NCDO 712
Niven, G. W. (1991) · Journal of General Microbiology · doi:10.1099/00221287-137-5-1207 · Cited by 75
Monnet, V., Bockelmann, W., Gripon, J. C., & Teuber, M. (1989) · Applied Microbiology and Biotechnology · doi:10.1007/bf00262446 · Cited by 75
Characterization of X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. lactis
Lloyd, R. J., & PRITCHARD, G. G. (1991) · Microbiology · doi:10.1099/00221287-137-1-49 · Cited by 73
A simple procedure using trinitrobenzenesulphonic acid for monitoring proteolysis in cheese
Polychroniadou, A. (1988) · Journal of Dairy Research · doi:10.1017/s0022029900033379 · Cited by 72
Yan, T., Azuma, N., Kaminogawa, S., & YAMAUCHI, K. (1987) · Applied and Environmental Microbiology · doi:10.1128/aem.53.10.2296-2302.1987 · Cited by 71
Pettersson, H.-E., & Sjöstrom, G. (1975) · Journal of Dairy Research · doi:10.1017/s002202990001534x · Cited by 71
Development of texture and flavour in cheese and other fermented products
Green, M. L., & Manning, D. J. (1982) · Journal of Dairy Research · doi:10.1017/s002202990002286x · Cited by 71
Microbiological and Chemical Aspects of Cheddar Cheese Ripening. A Review
Marth, E. H. (1963) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(63)89174-2 · Cited by 71
Specificity of a cell wall proteinase from Streptococcus lactis NCDO763 towards bovine β-casein
Monnet, V., Bars, D. L., & Gripon, J. C. (1986) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1986.tb01681.x · Cited by 71
Booth, M., Fhaoláin, Í. N., Jennings, P. V., & O’Cuinn, G. (1990) · Journal of Dairy Research · doi:10.1017/s0022029900026649 · Cited by 69
(1989) · Australian Journal of Dairy Technology · Cited by 67
Pélissier, J. P., Mercier, J. C., & Dumas, B. R. (1974) · annales de biologie animale biochimie biophysique · doi:10.1051/rnd:19740211 · Cited by 66
Action of a cell wall proteinase (PI) from Streptococcus cremoris HP on bovine β-casein.
Visser, S., Slangen, C. J., Exterkate, F. A., & de Veer, G. J. C. M. (1988) · Applied Microbiology and Biotechnology · doi:10.1007/bf00258352 · Cited by 65
Self-citationTrieu‐Cuot, P., & Gripon, J. C. (1982) · Journal of Dairy Research · doi:10.1017/s0022029900022640 · Cited by 65
Enzyme Activities of Lactic Streptococci and Their Role in Maturation of Cheese: A Review
Kamaly, K. M., & Marth, E. H. (1989) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(89)79318-8 · Cited by 65
(1978) · Socio-Environmental Systems Modeling · Cited by 64
Baankreis, R., & Exterkate, F. A. (1991) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(11)80305-x · Cited by 64
Specificity of milk-clotting enzymes towards bovine κ-casein
Drøhse, H. B., & Foltmann, B. (1989) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(89)90039-3 · Cited by 64
Minagawa, E., Kaminogawa, S., Tsukasaki, F., & YAMAUCHI, K. (1989) · Journal of Food Science · doi:10.1111/j.1365-2621.1989.tb05960.x · Cited by 64
Isolation and Characterization of a Prolidase fromStreptococcus cremorisH61
Kaminogawa, S., Azuma, N., Hwang, I.-K., Suzuki, Y., & YAMAUCHI, K. (1984) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1984.10866639 · Cited by 63
SPECTROPHOTOMETRIC ASSAY OF PLASMIN AND PLASMINOGEN IN BOVINE MILK.
Rollema, H. S., Visser, S., & Poll, J. K. (1983) · Milk science international/Milchwissenschaft · Cited by 63
Self-citationDebittering mechanism of bitter peptides from milk casein by wheat carboxypeptidase
Umetsu, H., Matsuoka, H., & Ichishima, E. (1983) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00115a013 · Cited by 62
Proteolysis of αs1-casein by chymosin: influence of pH and urea
Mulvihill, D. M., & Fox, P. F. (1977) · Journal of Dairy Research · doi:10.1017/s0022029900020483 · Cited by 62
Purification and characterization of a novel metalloendopeptidase from Streptococcus cremoris H61
Yan, T., Azuma, N., Kaminogawa, S., & YAMAUCHI, K. (1987) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1987.tb10796.x · Cited by 61
Purification and Properties of a Dipeptidase fromStreptococcus cremoris
Hwang, I.-K., Kaminogawa, S., & YAMAUCHI, K. (1981) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.45.159 · Cited by 60
Kaminogawa, S., & YAMAUCHI, K. (1972) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.36.2351 · Cited by 59
Flavour development in cheeses.
Law, B. A., & Davies, F. L. (1984) · Cited by 58
Probable role of the Strecker degradation of amino acids in development of cheese flavor
Keeney, M., & Day, E. A. (1957) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(57)94566-6 · Cited by 58
Exterkate, F. A., Alting, A. C., & Slangen, C. J. (1991) · Biochemical Journal · doi:10.1042/bj2730135 · Cited by 58
Purification and characterization of a cell wall proteinase fromStreptococcus lactisNCDO 763
Monnet, V., Bars, D. L., & Gripon, J. C. (1987) · Journal of Dairy Research · doi:10.1017/s0022029900025383 · Cited by 57
Action of a cell wall proteinase from Lactococcus lactis subsp. cremoris SK11 on bovine ? s1-casein
Reid, J., Moore, C., Midwinter, G. G., & PRITCHARD, G. G. (1991) · Applied Microbiology and Biotechnology · doi:10.1007/bf00184690 · Cited by 57
β-Casein Degradation in Gouda and Cheddar Cheese
Creamer, L. K. (1975) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(75)84562-0 · Cited by 56
Proline-specific peptidases ofStreptococcus cremorisAM2
Booth, M., Donnelly, W. J., Fhaoláin, Í. N., Jennings, P. V., & O’Cuinn, G. (1990) · Journal of Dairy Research · doi:10.1017/s0022029900026637 · Cited by 56
Prolidase activity ofLactococcus lactissubsp.cremorisAM2: partial purification and characterization
Booth, M., Jennings, V., Fhaoláin, Í. N., & O’Cuinn, G. (1990) · Journal of Dairy Research · doi:10.1017/s0022029900026868 · Cited by 56
Degradation of Casein Components by Acid Protease of Bovine Milk
Kaminogawa, S., YAMAUCHI, K., 宮沢, 貞., & Koga, Y. (1980) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(80)82996-1 · Cited by 56
Proteolysis and flavour development in Cheddar cheese.
Jw, A., Ig, D., & Dulley (1983) · Australian Journal of Dairy Technology · Cited by 56
Visser, S., Robben, A. J. P. M., & Slangen, C. J. (1991) · Applied Microbiology and Biotechnology · doi:10.1007/bf00169753 · Cited by 55
Self-citationNinhydrin Assay For Proteolysis in Ripening Cheese
PEARCE, K. E. N., KARAHALIOS, D. A., & Friedman, M. (1988) · Journal of Food Science · doi:10.1111/j.1365-2621.1988.tb07723.x · Cited by 55
Chemical production of essential Cheddar flavour compounds
Manning, D. J. (1979) · Journal of Dairy Research · doi:10.1017/s0022029900017556 · Cited by 55
Kaminogawa, S., Yan, T., Azuma, N., & YAMAUCHI, K. (1986) · Journal of Food Science · doi:10.1111/j.1365-2621.1986.tb13098.x · Cited by 53
The roles of native milk proteinase and its zymogen during proteolysis in normal bovine milk
de Rham, O., & Andrews, A. T. (1982) · Journal of Dairy Research · doi:10.1017/s002202990002272x · Cited by 53
Peptidase activities in Group N streptococci
Mou, L., Sullivan, J. J., & Jago, G. R. (1975) · Journal of Dairy Research · doi:10.1017/s002202990001517x · Cited by 52
ENZYMES INVOLVED IN THE DEGRADATION AND UTILIZATION OF CASEIN IN LACTOCOCCUS-LACTIS
Laan, H., Smid, E. J., Tan, P. S. T., & Konings, W. N. (1989) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 48
Extracellular Peptidases in Group N Streptococci used as Cheese Starters
Law, B. A. (1979) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1979.tb00844.x · Cited by 47
Aminopeptidase Profiles of Lactic Streptococci
Kaminogawa, S., Ninomiya, T., & YAMAUCHI, K. (1984) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(84)81604-5 · Cited by 44
Influence of aggregation on the susceptibility of casein to proteolysis
Fox, P. F. (1970) · Journal of Dairy Research · doi:10.1017/s0022029900013200 · Cited by 43
Kaminogawa, S., & YAMAUCHI, K. (1972) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1972.10860582 · Cited by 43
Isolation and characterization of a prolidase from Streptococcus cremoris H61.
Kaminogawa, S., Azuma, N., Hwang, I.-K., Suzuki, Y., & YAMAUCHI, K. (1984) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.48.3035 · Cited by 43
牛β‐カゼインに対する作用におけるキモシン(レンニン)の特異性
Visser, S., & Slangen, K. J. (1977) · Cited by 42
Self-citationExterkate, F. A., & de Veer, G. J. C. M. (1987) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(87)80020-6 · Cited by 40
Cheddar cheese flavour studies: II. Relative flavour contributions of individual volatile component
Manning, D. J. (1979) · Journal of Dairy Research · doi:10.1017/s0022029900017544 · Cited by 40
Kolstad, J., & Law, B. A. (1985) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1985.tb01484.x · Cited by 39
New Aspects of Naturally Occurring Proteases in Bovine Milk
Reimerdes, E. H. (1983) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(83)81979-1 · Cited by 39
de Jong, L. (1977) · Socio-Environmental Systems Modeling · Cited by 38
Specificity of bovine plasmin in its action on bovine α-S2-casein
Visser, S., Slangen, K. J., Alting, A. C., & Vreeman, H. J. (1989) · Milk science international/Milchwissenschaft · Cited by 37
Self-citationGroves, M. L., Gordon, W. G., Kalan, E. B., & Jones, S. B. (1973) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(73)85219-1 · Cited by 37
The action of rennets on the caseins: I. Rennin action on β-casein-B in solution
Creamer, L. K., Mills, O. E., & Richards, E. C. M. (1971) · Journal of Dairy Research · doi:10.1017/s0022029900019385 · Cited by 36
Peptidase activities in debittering and nondebittering strains of lactobacilli
ABBOUDI, M. E., Soda, M. E., Pandian, S., Barreau, M., Trépanier, G., & SIMARD, R. E. (1992) · International Dairy Journal · doi:10.1016/0958-6946(92)90044-m · Cited by 36
Cliffe, A. J., Revell, D. F., & Law, B. A. (1989) · Food Chemistry · doi:10.1016/0308-8146(89)90083-6 · Cited by 36
Effect of Milk-Clotting Enzymes on Cheese Yield
Ustunol, Z., & Hicks, C. L. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78639-0 · Cited by 36
Intracellular proteinase ofLactococcus lactissubsp.lactisNCDO 763
Muset, G., Monnet, V., & Gripon, J. C. (1989) · Journal of Dairy Research · doi:10.1017/s0022029900029344 · Cited by 36
Manning, D. J., & Price, J. C. (1977) · Journal of Dairy Research · doi:10.1017/s0022029900020306 · Cited by 35
Action of plasmin on bovine β-casein in a membrane reactor
Visser, S., Noorman, H. J., Slangen, C. J., & Rollema, H. S. (1989) · Journal of Dairy Research · doi:10.1017/s0022029900028764 · Cited by 35
Self-citationAssociation of plasminogen with bovine milk fat globule membrane
Hofmann, C., Keenan, T. W., & Eigel, W. N. (1979) · International Journal of Biochemistry · doi:10.1016/0020-711x(79)90123-x · Cited by 34
Location and characterization of aminopeptidase N in Lactococcus lactis subsp. cremoris HP
Exterkate, F. A., de Jong, M., de Veer, G. J. C. M., & Baankreis, R. (1992) · Applied Microbiology and Biotechnology · doi:10.1007/bf00174202 · Cited by 34
Bitter Peptide Isolated from Milk Cultures of Streptococcus cremoris
Gordon, D. F., & Speck, M. L. (1965) · Applied Microbiology · doi:10.1128/aem.13.4.537-542.1965 · Cited by 33
Milk-Clotting Enzymes. 1. Proteolysis During Cheese Making in Relation to Estimated Losses of Yield
Emmons, D. B., Beckett, D. C., & Binns, M. R. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78879-0 · Cited by 31
Desmazeaud, M., & Zevaco, C. (1976) · annales de biologie animale biochimie biophysique · doi:10.1051/rnd:19760608 · Cited by 31
Casein micelle structure: susceptibility of various casein systems to proteolysis
Fox, P. F., & Guiney, J. (1973) · Journal of Dairy Research · doi:10.1017/s0022029900014552 · Cited by 31
Heat‐Shocked Lactobacilli for Acceleration of Cheddar Cheese Ripening
ABBOUDI, M. E., Pandian, S. K., Trépanier, G., SIMARD, R. E., & Lee, B.-W. (1991) · Journal of Food Science · doi:10.1111/j.1365-2621.1991.tb14612.x · Cited by 29
Proteolysis in cheese investigated by high performance liquid chromatography
Christensen, T. M. I. E., Kristiansen, K. R., & Madsen, J. S. (1989) · Journal of Dairy Research · doi:10.1017/s0022029900029411 · Cited by 29
Revue bibliographique : la fraction protéose-peptones du lait
Pâquet, D. (1989) · Le Lait · doi:10.1051/lait:198911 · Cited by 29
Monnet, V., Bars, D. L., Neviani, E., Neviani, E., & Gripon, J. C. (1987) · Le Lait · doi:10.1051/lait:198713 · Cited by 29
Exterkate, F. A. (1977) · Journal of Bacteriology · doi:10.1128/jb.129.3.1281-1288.1977 · Cited by 29
Gene Organization and Expression in Mesophilic Lactic Acid Bacteria
de Vos, W. M., Vos, P., Simons, G., & David, S. (1989) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(89)79503-5 · Cited by 28
Purification and debittering effect of aminopeptidase II from Penicillium caseicolum
Matsuoka, H., Fuke, Y., Kaminogawa, S., & YAMAUCHI, K. (1991) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00008a007 · Cited by 27
Bockelmann, W., Monnet, V., Geis, A., Teuber, M., & Gripon, J. C. (1989) · Applied Microbiology and Biotechnology · doi:10.1007/bf00258409 · Cited by 25
Production of chymosin (EC 3.4.23.4) by microorganisms and its use for cheesemaking.
Teuber, M. (1990) · Bulletin. International Dairy Federation · Cited by 24
Direct Observation of Fine Structures of Bacteria in Ripened Cheddar Cheese by Electron Microscopy
UMEMOTO, Y., Sato, Y., & Kito, J. (1978) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.42.227 · Cited by 24
Law, J., Vos, P., Hayes, F., Daly, C., de Vos, W. M., & Fitzgerald, G. F. (1992) · Journal of General Microbiology · doi:10.1099/00221287-138-4-709 · Cited by 24
Cheese Yield Experiments and Proteolysis by Milk-Clotting Enzymes
Emmons, D. B., & Binns, M. R. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78882-0 · Cited by 24
Exterkate, F. A., & de Veer, G. J. C. M. (1989) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(89)80048-7 · Cited by 24
Purification and Properties of Intracellular Proteinase from Streptococcus cremoris
Ohmiya, K., & Sato, Y. (1975) · Applied Microbiology · doi:10.1128/am.30.5.738-745.1975 · Cited by 23
On the possibility of accelerating the ripening of Gouda cheese; a comment
Exterkate, F. A. (1987) · Netherlands milk and dairy journal · Cited by 23
Determination of the ripening time of Edam and Gouda cheese by chemical analysis
Venema, D. P., Herstel, H., & Elenbaas, H. L. (1987) · Netherlands milk and dairy journal · Cited by 23
Noomen, A. (1978) · Socio-Environmental Systems Modeling · Cited by 23
Autoproteolysis of the Extracellular Serine Proteinase of Lactococcus lactis subsp. cremoris Wg2
Laan, H., & Konings, W. N. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.9.2586-2590.1991 · Cited by 22
Humbert, G., Guingamp, M.-F., Kouomegne, R., & Linden, G. (1990) · Journal of Dairy Research · doi:10.1017/s0022029900026716 · Cited by 21
Flavour of Milk and Milk Products
Manning, D. J., & Nürsten, H. E. (1985) · Springer eBooks · doi:10.1007/978-94-009-4950-8_8 · Cited by 19
Kinetic Properties of a Dipeptidase fromStreptococcus cremoris
Hwang, I.-K., Kaminogawa, S., & YAMAUCHI, K. (1982) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1982.10865544 · Cited by 19
軟質類似チーズ(Meshanger型)におけるたんぱく質分解酵素活性 II 子牛レンネットの活性
Noomen, A. (1978) · Cited by 19
Kinetic properties of a dipeptidase from Streptococcus cremoris.
Hwang, I.-K., Kaminogawa, S., & YAMAUCHI, K. (1982) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.46.3049 · Cited by 19
Cliffe, A. J., & Law, B. A. (1991) · Food Biotechnology · doi:10.1080/08905439109549787 · Cited by 18
Cellular Location and Characteristics of Peptidase Enzymes in Lactic Streptococci
Schmidt, R. H., Morris, H. A., & McKay, L. L. (1977) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(77)83924-6 · Cited by 17
Visser, S., Slangen, K. J., & Hup, G. (1975) · Netherlands milk and dairy journal · Cited by 17
Self-citationHigh-performance liquid chromatography determination of the extent of proteolysis in gouda cheese
Haasnoot, W., Stouten, P. F. W., & Venema, D. P. (1989) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)93131-0 · Cited by 16
Fox, P., Guinee, T., Cogan, T., & McSweeney, P. (2017) · Springer eBooks · doi:10.1007/978-1-4899-7681-9_7 · Cited by 16
Cheddar Cheese Made with Bovine Pepsin. I. Yield and Quality of Cheese.5
Emmonsce, D. B., Reiser, B., Giroux, R. N., & Stanley, D. W. (1976) · Canadian Institute of Food Science and Technology Journal · doi:10.1016/s0315-5463(76)73674-5 · Cited by 15
The importance of plasmin in Swiss-type cheese ripening.
Ollikainen, P. (1990) · Brief Communications of the XXIII International Dairy Congress, Montreal, October 8-12, 1990, Vol. I. · Cited by 15
Decomposition of milk proteins during the ripening of cheese. 1. Enzymatic hydrolysis of -casein
Pahkala, E., Pihlanto-Leppälä, A., Laukkanen, M., & Antila, V. (1989) · Jukuri (Natural Resources Institute Finland (Luke)) · Cited by 13
Milk-Clotting Enzymes. 2. Estimating Cheese Yield Losses from Proteolysis During Cheese Making
Emmons, D. B. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78880-7 · Cited by 13
Purification and Properties of Intracellular Proteinase from Streptococcus cremoris
Ohmiya, K., & Sato, Y. (1975) · Applied Microbiology · doi:10.1128/aem.30.5.738-745.1975 · Cited by 13
Titration – a rapid method for the determination of proteolysis in cheese
Ollikainen, P. (1990) · Journal of Dairy Research · doi:10.1017/s0022029900026728 · Cited by 11
The oxidation-reduction potential of cheese.
Galesloot, T. E. (1960) · Cited by 10
Production, processing, and engineering of the Lactococcus lactis SK11 proteinase.
de Vos, W. M., Boerrigter, I. J., Vos, P., Bruinenberg, P. M., Siezen, R. J., Dunny, G. M., Cleary, P. P., & McKay, L. L. (1991) · Cited by 9
Stability and activity of plasmin in UF retentate and cheese.
Hansen, K. G. (1990) · Cited by 7
Maturation of the cell envelope-associated proteinase of lactococcus lactis.
Haandrikman, A. J. (1990) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 7
Watanabe, M., SHIMIZU, J., & Arai, S. (1990) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.54.3351 · Cited by 5
Milk-Clotting Enzymes. 3. Design of. Experiments on Proteolysis During Cheese Making
Emmons, D. B., & Binns, M. R. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78881-9 · Cited by 4
Ichishima, E., Kawai, Y., Takeuchi, M., & Ahiko, K. (1986) · Current Microbiology · doi:10.1007/bf01568159 · Cited by 4
Cheese yields resulting from the use of different animal rennets.
Thomasow, J. (1980) · Milk science international/Milchwissenschaft · Cited by 2
The extracellular proteinase of Lactococcus lactis
Laan, H. W. F. (1991) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 2
Watanabe, M., Shimizu, J., & Arai, S. (1990) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1990.10870485 · Cited by 1
Research works printed but not linked: 38
- Aston, 1986, Contribution of the components of the water-soluble fraction to the flavour of Cheddar cheese, N.Z. J. Dairy Sci. Technol., 21, 229
- Corradini, 1978, Grana cheesemaking employing bovine rennet with high pepsin content, Sci. Teen. Latt. Cas., 29, 382
- Creamer, 1976, A further study of the action of rennin on β-casein, N.Z. J. Dairy Sci. Technol., 11, 30
- Creamer, 1974, Identification of the primary degradation product of αs1- casein in Cheddar cheese, N.Z. J. Dairy Sci. Technol., 9, 9
- de Koning, 1981, Milk clotting enzymes. 2. Use of rennet substitutes, Voedingsmiddelentechnologie, 14, 27
- Desmazeaud, 1979, Isolation and general properties of two intracellular aminopeptidases of Streptococcus diacetylactis, Milchwissenschaft, 34, 606
- Exterkate, 1976, Comparison of strains of Streptococcus cremoris for proteolytic activities associated with the cell wall, Neth. Milk Dairy J., 30, 95
- Exterkate, 1987, Acceleration of the ripening process of Gouda cheese by using heat-treated mixed-strain starter cells, Neth. Milk Dairy J., 41, 307
- Exterkate, 1971, Pyrrolidone carboxylyl peptidase activity in bitter and non-bitter strains of Streptococcus cremoris, Neth. Milk Dairy J., 25, 240
- Fox, 1988, Rennets and their action in cheese manufacture and ripening, Biotechnol. Appl. Biochem., 10, 522
- Fox, 1987, Italian cheeses, Vol. 2, 221
- Grufferty, 1988, Factors affecting the release of plasmin activity from casein micelles, N.Z. J. Dairy Sci. Technol., 23, 153
- Halpaap, 1977, Milchproteinasen. VI. Vergleichende Isolierung von Plasminogen aus Rinderblut und einer Proteinase aus Kuhmilch, Milchwissenschaft, 32, 341
- Jarrett, 1982, A simple method for estimating free amino acids in Cheddar cheese, Aust. J. Dairy Technol., 37, 55
- Kilara, 1985, Proteolytic enzymes and their applications in the dairy industry, Indian J. Dairy Sci., 37, 241
- Law, B. A. 1982. Cheeses. Page 147 in Economic Microbiology. Vol. 7. Fermented Foods. A. H. Rose, ed. Academic Press, London, Engl.
- Law, 1987, Proteolysis in relation to normal and accelerated cheese ripening, Vol. 1, 365
- Manning, 1978, The chemical basis of Cheddar flavor, Dairy Ind. Int., 43, 37
- Mills, 1978, Release of cell wall-associated proteinases from lactic streptococci, N. Z. J. Dairy Sci. Technol., 13, 209
- Mulder, 1952, Taste and flavour forming substances in cheese, Neth. Milk Dairy J., 6, 157
- Mulvihill, 1978, Proteolysis of bovine β-casein by chymosin: influence of pH, urea and sodium chloride, Ir. J. Food Sci. Technol., 2, 135
- Ollikainen, 1988, A study of plasmin activity during ripening of Swiss-type cheese, Milchwissenschaft, 43, 497
- Reimerdes, 1974, Milchproteasen. I. Micellenassoziierte Protease-Anreicherung und Hydrolyse von Caseinen, Milchwissenschaft, 29, 517
- Reimerdes, 1976, Milch-Proteinasen. VII. Fraktionierung von Komponenten des Proteinasen-Inhibitor-Systems der Milch, Milchwissenschaft, 31, 329
- Richardson, 1983, The proteinases of bovine milk and the effect of pasteurization on their activity, N.Z. J. Dairy Sci. Technol., 18, 233
- Richardson, 1973, Casein proteolysis and bitter peptides in Cheddar cheese, N.Z. J. Dairy Sci. Technol., 8, 46
- Richardson, 1984, Plasmin activity in commercial caseins and caseinates, N.Z. J. Dairy Sci. Technol., 19, 63
- Rollema, 1986, The alkaline milk proteinase system: kinetics and mechanism of heat-inactivation, Milchwissenschaft, 41, 536
- Rollema, 1981, On the determination, purification and characterization of the alkaline proteinase from bovine milk, Neth. Milk Dairy J., 35, 396
- Snoeren, 1979, Milk proteinase, its isolation and action on αs1-and β-casein, Milchwissenschaft, 34, 528
- Stadhouders, 1975, Factors affecting bitter flavour in Gouda cheese, Neth. Milk Dairy J., 29, 335
- Stadhouders, 1983, Bitter flavour in cheese. 1. Mechanism of the formation of the bitter flavour defect in cheese, Neth. Milk Dairy J., 37, 157
- Thomasow, 1980, Käseausbeute bei Verwendung verschiedener tierischer Labpräparate, Milchwissenschaft, 35, 212
- Visser, 1977, Contribution of enzymes from rennet, starter bacteria and milk to proteolysis and flavour development in Gouda cheese. 3. Protein breakdown: analysis of the soluble nitrogen and amino acid nitrogen fractions, Neth. Milk Dairy J., 31, 210
- Visser, 1977, Contribution of enzymes from rennet, starter bacteria and milk to proteolysis and flavour development in Gouda cheese. 4. Protein breakdown: a gel electrophoretic study, Neth. Milk Dairy J., 31, 247
- Visser, 1981, Proteolytic enzymes and their action on milk proteins. A review, Neth. Milk Dairy J., 35, 65
- Visser, 1977, On the specificity of chymosin (rennin) in its action on bovine β- casein, Neth. Milk Dairy J., 31, 16
- Visser, 1983, Bitter flavour in cheese. 3. Comparative gel-chromatographic analysis of hydrophobic peptide fractions from twelve Gouda-type cheeses and identification of bitter peptides isolated from a cheese made with Streptococcus cremoris strain HP, Neth. Milk Dairy J., 37, 181
Cited by
Sorted by citations
Biochemistry of cheese ripening
McSweeney, P. L. H. (2004) · International Journal of Dairy Technology · doi:10.1111/j.1471-0307.2004.00147.x · Cited by 1,074
Flavor of Cheddar Cheese: A Chemical and Sensory Perspective
Singh, T. K., Drake, M. A., & Cadwallader, K. R. (2003) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2003.tb00021.x · Cited by 423
Proteolysis in cheese during ripening
Fox, P. F., & McSweeney, P. L. H. (1996) · Food Reviews International · doi:10.1080/87559129609541091 · Cited by 407
Gobbetti, M., Stepaniak, L., De Angelis, M., Corsetti, A., & Di Cagno, R. (2002) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408690290825538 · Cited by 344
Malolactic fermentation in wine - beyond deacidification
Liu, S. (2002) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2002.01589.x · Cited by 321
Metadata
- Authors
- Visser, S.
- Affiliations
- Nederlands Instituut Voor Zuivel Oonderzoek (NL)
- Corresponding author
- Visser, Servaas
- Venue
- Journal of Dairy Science
- Publisher
- American Dairy Science Association
- Published
- 1993-01
- Volume
- 76
- Issue
- 1
- Pages
- 329-350
- ISSN
- 0022-0302 (ISSN-L)
- OpenAlex
- W2027602106
- Cited by
- 305
- References
- 195
- Citations by year
- 2026: 4 · 2025: 1 · 2024: 4 · 2023: 6 · 2022: 7 · 2021: 6 · 2020: 2 · 2019: 4 · 2018: 8 · 2017: 10 · 2016: 7 · 2015: 2 · 2014: 13 · 2013: 5 · 2012: 5
- FWCI
- 34.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Dairy Science (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Enzyme Production and Characterization
- Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
- Keywords
- proteolytic enzymes, cheese ripening, cheese flavor, starter bacteria, milk-clotting enzyme, bitter peptides, cheese texture, amino acid conversion, free amino acids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review