The DOI matches its Crossref record.
Natural history of intracranial cavernous malformations
Abstract
✓ The authors have reviewed the clinical records of 110 patients with intracranial cavernous malformations diagnosed by histological examination and/or magnetic resonance imaging over a mean follow-up period of 4.71 years. These cases were divided, based on their presentation, into a hemorrhage group, a seizure group, and an incidentally diagnosed group. The rate of subsequent symptomatic bleeding was investigated in relation to age at onset, sex, and location of the initial lesion. A high rate of subsequent symptomatic bleeding episodes was found in the hemorrhage group, especially among younger females. The nonhemorrhagic-onset cases had a very low incidence of bleeding. The outcome was generally good, except in patients with lesions in the basal ganglia and brainstem. These findings will be helpful in planning a rational therapeutic strategy for intracranial cavernous malformations.
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Cited by
Flemming, K. D., Graff-Radford, J., Aakre, J., Kantarci, K., Lanzino, G., Brown, R. D., Mielke, M. M., Roberts, R. O., Kremers, W., Knopman, D. S., et al. (2017) · JAMA Neurology · doi:10.1001/jamaneurol.2017.0439 · Cited by 136
Metadata
- Authors
- Aiba, T., Tanaka, R., Koike, T., Kameyama, S., Takeda, N., & Komata, T.
- Venue
- Journal of Neurosurgery
- Published
- 1995-07
- Volume
- 83
- Issue
- 1
- Pages
- 56-59
- ISSN
- 0022-3085 (ISSN-L)
- OpenAlex
- W2002659392
- Cited by
- 426
- References
- 0
- FWCI
- 5.51
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
