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Myotrophic Activity of 19-Nortestosterone and Other Steroids Determined by Modified Levator Ani Muscle Method.

Hershberger, L. G., Shipley, E. G., Meyer, R. K.·1953·Experimental Biology and Medicine

Abstract

An 8-day rat levator ani muscle assay for myotrophic activity is presented. Preliminary steroid screening results indicate that 19-nortestosterone and other 19-nor analogs of androgens promise to be effective protein-anabolic, and relatively weak androgenic agents. Using the same dose levels of 19-nortestosterone and testosterone, equal myotrophic responses were produced, yet 19-nortestosterone showed only weak androgenic activity and testosterone exhibited strong androgenic activity. Androsterone possesses relatively strong androgenic and only weak myotrophic activity.

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Metadata

Authors
Hershberger, L. G., Shipley, E. G., & Meyer, R. K.
Venue
Experimental Biology and Medicine
Published
1953-05-01
Volume
83
Issue
1
Pages
175-180
ISSN
  • 0071-3384 (ISSN-L)
  • 1535-3702
  • 1535-3699
OpenAlex
W2326357482
Cited by
384
References
0
FWCI
6.27
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Myotrophic Activity of 19-Nortestosterone and Other Steroids Determined by Modified Levator Ani Muscle Method. https://app.cochat.ai/papers/10.3181/00379727-83-20301
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Hershberger, L. G., Shipley, E. G., & Meyer, R. K. (1953). Myotrophic Activity of 19-Nortestosterone and Other Steroids Determined by Modified Levator Ani Muscle Method. Experimental Biology and Medicine. https://doi.org/10.3181/00379727-83-20301

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.