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Cited by 696

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Quinolone and Macrolide Resistance in Campylobacter jejuni and C. coli: Resistance Mechanisms and Trends in Human Isolates

Open access
Engberg, Jørgen, Aarestrup, Frank M., Taylor, Diane E., Gerner-Smidt, Peter, Nachamkin, Irving·2001·Emerging Infectious Diseases

Abstract

The incidence of human Campylobacter jejuni and C. coli infections has increased markedly in many parts of the world in the last decade as has the number of quinolone-resistant and, to a lesser extent, macrolide-resistant Campylobacter strains causing infections. We review macrolide and quinolone resistance in Campylobacter and track resistance trends in human clinical isolates in relation to use of these agents in food animals. Susceptibility data suggest that erythromycin and other macrolides should remain the drugs of choice in most regions, with systematic surveillance and control measures maintained, but fluoroquinolones may now be of limited use in the empiric treatment of Campylobacter infections in many regions.

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Crossref · 10.3201/eid0701.010104

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Metadata

Authors
Engberg, J., Aarestrup, F. M., Taylor, D. E., Gerner-Smidt, P., & Nachamkin, I.
Venue
Emerging Infectious Diseases
Published
2001-01
Volume
7
Issue
1
Pages
24-34
ISSN
  • 1080-6040 (ISSN-L)
  • 1080-6059
OpenAlex
W2107508284
Cited by
696
References
1
FWCI
65.86
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Quinolone and Macrolide Resistance in Campylobacter jejuni and C. coli: Resistance Mechanisms and Trends in Human Isolates. https://app.cochat.ai/papers/10.3201/eid0701.010104
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Engberg, J., Aarestrup, F. M., Taylor, D. E., Gerner-Smidt, P., & Nachamkin, I. (2001). Quinolone and Macrolide Resistance in Campylobacter jejuni and C. coli: Resistance Mechanisms and Trends in Human Isolates. Emerging Infectious Diseases. https://doi.org/10.3201/eid0701.010104

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.