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Engineering out the Risk of Infection with Urinary Catheters
Open accessAbstract
Catheter-associated urinary tract infection (CAUTI) is the most common nosocomial infection. Each year, more than 1 million patients in U.S. acute-care hospitals and extended-care facilities acquire such an infection; the risk with short-term catheterization is 5% per day. CAUTI is the second most common cause of nosocomial bloodstream infection, and studies suggest that patients with CAUTI have an increased institutional death rate, unrelated to the development of urosepsis. Novel urinary catheters impregnated with nitrofurazone or minocycline and rifampin or coated with a silver alloy-hydrogel exhibit antiinfective surface activity that significantly reduces the risk of CAUTI for short-term catheterizations not exceeding 2-3 weeks.
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Cited by
Hooton, T. M., Bradley, S. F., Cardenas, D. D., Colgan, R., Geerlings, S. E., Rice, J. C., Saint, S., Schaeffer, A. J., Tambayh, P. A., Tenke, P., et al. (2010) · Clinical Infectious Diseases · doi:10.1086/650482 · Cited by 2,099
The epidemiology of urinary tract infection
Foxman, B. (2010) · Nature Reviews Urology · doi:10.1038/nrurol.2010.190 · Cited by 1,771
Candida biofilms and their role in infection
Douglas, L. J. (2003) · Trends in Microbiology · doi:10.1016/s0966-842x(02)00002-1 · Cited by 1,150
Critical Role of Bcr1-Dependent Adhesins in C. albicans Biofilm Formation In Vitro and In Vivo
Nobile, C. J., Andes, D. R., Nett, J. E., Smith, F. J., Yue, F., Phan, Q.-T., Edwards, J. E., Filler, S. G., & Mitchell, A. P. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020063 · Cited by 507
Drug/device combinations for local drug therapies and infection prophylaxis
Wu, P., & Grainger, D. W. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2005.11.031 · Cited by 491
Metadata
- Authors
- Maki, D. G., & Tambyah, P. A.
- Venue
- Emerging Infectious Diseases
- Published
- 2001-03
- Volume
- 7
- Issue
- 2
- Pages
- 342-347
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2159668600
- Cited by
- 750
- References
- 0
- FWCI
- 11.41
- Type
- journal article
- Language
- en
- Open access
- diamond
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